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Aliases for MIR198 Gene

Subcategory (RNA class) for MIR198 Gene

miRNA

Quality Score for this RNA gene is

2

Aliases for MIR198 Gene

  • MicroRNA 198 2 3
  • Hsa-Mir-198 3
  • MiR-198 3
  • MIRN198 3

External Ids for MIR198 Gene

Previous HGNC Symbols for MIR198 Gene

  • MIRN198

Previous GeneCards Identifiers for MIR198 Gene

  • GC03M121599
  • GC03M120112

Summaries for MIR198 Gene

Entrez Gene Summary for MIR198 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR198 Gene

MIR198 (MicroRNA 198) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR198 Gene

Genomics for MIR198 Gene

Genomic Location for MIR198 Gene

Chromosome:
3
Start:
120,395,668 bp from pter
End:
120,395,729 bp from pter
Size:
62 bases
Orientation:
Minus strand

Genomic View for MIR198 Gene

Genes around MIR198 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR198 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR198 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR198 Gene

No data available for Regulatory Elements for MIR198 Gene

Proteins for MIR198 Gene

Post-translational modifications for MIR198 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR198 Gene

Domains & Families for MIR198 Gene

Gene Families for MIR198 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR198: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR198 Gene

Function for MIR198 Gene

Phenotypes for MIR198 Gene

GenomeRNAi human phenotypes for MIR198:
genes like me logo Genes that share phenotypes with MIR198: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR198 Gene

Localization for MIR198 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR198 Gene

Pathways & Interactions for MIR198 Gene

SuperPathways for MIR198 Gene

No Data Available

Interacting Proteins for MIR198 Gene

Gene Ontology (GO) - Biological Process for MIR198 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR198 Gene

Drugs & Compounds for MIR198 Gene

No Compound Related Data Available

Transcripts for MIR198 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for MIR198 Gene

No ASD Table

Relevant External Links for MIR198 Gene

GeneLoc Exon Structure for
MIR198
ECgene alternative splicing isoforms for
MIR198

No data available for mRNA/cDNA for MIR198 Gene

Expression for MIR198 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR198 Gene

Orthologs for MIR198 Gene

No data available for Orthologs and Evolution for MIR198 Gene

Paralogs for MIR198 Gene

No data available for Paralogs for MIR198 Gene

Variants for MIR198 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR198 Gene

Variant ID Type Subtype PubMed ID
nsv877376 CNV Gain 21882294
nsv829698 CNV Gain 17160897

Relevant External Links for MIR198 Gene

HapMap Linkage Disequilibrium report
MIR198

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR198 Gene

Disorders for MIR198 Gene

Relevant External Links for MIR198

Genetic Association Database (GAD)
MIR198
Human Genome Epidemiology (HuGE) Navigator
MIR198
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR198

No disorders were found for MIR198 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR198 Gene

Publications for MIR198 Gene

  1. MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia. (PMID: 20347265) Xu Y. … Liu P. (Schizophr. Res. 2010) 3 48 67
  2. MiR-21, miR-34a, miR-198 and miR-217 as diagnostic and prognostic biomarkers for chronic pancreatitis and pancreatic ductal adenocarcinoma. (PMID: 25908274) Vychytilova-Faltejskova P. … Slaby O. (Diagn Pathol 2015) 3
  3. MiR-198 represses tumor growth and metastasis in colorectal cancer by targeting fucosyl transferase 8. (PMID: 25174450) Wang M. … Fang J.Y. (Sci Rep 2014) 3
  4. Livin expression may be regulated by miR-198 in human prostate cancer cell lines. (PMID: 23069480) Ye L. … Song X. (Eur. J. Cancer 2013) 3
  5. Downregulation of cell-free miR-198 as a diagnostic biomarker for lung adenocarcinoma-associated malignant pleural effusion. (PMID: 23354517) Han H.S. … Lee O.J. (Int. J. Cancer 2013) 3

Products for MIR198 Gene

Sources for MIR198 Gene

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