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Aliases for MIR1976 Gene

Subcategory (RNA class) for MIR1976 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1976 Gene

  • MicroRNA 1976 2 3 5
  • Hsa-Mir-1976 3

External Ids for MIR1976 Gene

Previous GeneCards Identifiers for MIR1976 Gene

  • GC00U923176
  • GC01P026883

Summaries for MIR1976 Gene

Entrez Gene Summary for MIR1976 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1976 Gene

MIR1976 (MicroRNA 1976) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1976 Gene

Genomics for MIR1976 Gene

Regulatory Elements for MIR1976 Gene

Enhancers for MIR1976 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F026580 1.7 FANTOM5 Ensembl ENCODE 12 +28.2 28159 3.8 PKNOX1 ARID4B YY1 FOS PAF1 SP5 NFYC MXD4 JUNB REST MIR1976 RPS6KA1 SFN ENSG00000226698 UBXN11 GPATCH3 NUDC PIGV SH3BGRL3 RN7SL679P
GH01F026499 1.8 FANTOM5 Ensembl ENCODE 11.3 -53.4 -53442 3.0 HDGF ARNT CREB3L1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZNF766 HMGN2 LOC101928324 ACTG1P20 NPM1P39 RPL17P9 LIN28A ENSG00000207302 LOC105376890 DHDDS RPL39P7
GH01F026618 1.9 FANTOM5 Ensembl ENCODE 10.4 +65.7 65660 4.4 CREB3L1 FEZF1 DMAP1 YY1 ZNF416 ZNF143 ZNF548 ZNF263 SP3 TBX21 HMGN2 ACTG1P20 NPM1P39 RPL17P9 AHDC1 GPATCH3 LOC101928324 WASF2 LOC105376890 ENSG00000207302
GH01F026782 1.7 FANTOM5 Ensembl ENCODE 10.7 +232.6 232605 9.2 CREB3L1 FEZF1 DMAP1 YY1 ZNF143 ZNF263 SP3 NFYC TBX21 MEF2D HMGN2 ZDHHC18 NPM1P39 RPS6KA1 PIGV LOC101928728 ENSG00000231344 RPL17P9 LOC101928324 ACTG1P20
GH01F026676 1.3 Ensembl ENCODE 11.5 +123.0 122959 1.8 HDGF ARNT MLX ARID4B ZNF2 ZNF143 FOS KDM4B DEK ZNF263 NPM1P39 PIGV LOC101928728 RPL17P9 HMGN2 LOC101928324 MIR1976 RPS6KA1 ACTG1P20 ENSG00000226698
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1976 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1976 Gene

Chromosome:
1
Start:
26,554,542 bp from pter
End:
26,554,593 bp from pter
Size:
52 bases
Orientation:
Plus strand

Genomic View for MIR1976 Gene

Genes around MIR1976 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1976 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1976 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1976 Gene

Proteins for MIR1976 Gene

Post-translational modifications for MIR1976 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1976 Gene

Domains & Families for MIR1976 Gene

Gene Families for MIR1976 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1976: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1976 Gene

Function for MIR1976 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1976 Gene

Localization for MIR1976 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1976 Gene

Pathways & Interactions for MIR1976 Gene

SuperPathways for MIR1976 Gene

No Data Available

Interacting Proteins for MIR1976 Gene

Gene Ontology (GO) - Biological Process for MIR1976 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1976 Gene

Transcripts for MIR1976 Gene

mRNA/cDNA for MIR1976 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1976 Gene

No ASD Table

Relevant External Links for MIR1976 Gene

GeneLoc Exon Structure for
MIR1976
ECgene alternative splicing isoforms for
MIR1976

Expression for MIR1976 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1976 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1976 Gene:

MIR1976
genes like me logo Genes that share expression patterns with MIR1976: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1976 Gene

Orthologs for MIR1976 Gene

Evolution for MIR1976 Gene

ENSEMBL:
Gene Tree for MIR1976 (if available)
TreeFam:
Gene Tree for MIR1976 (if available)

No data available for Orthologs for MIR1976 Gene

Paralogs for MIR1976 Gene

No data available for Paralogs for MIR1976 Gene

Variants for MIR1976 Gene

Sequence variations from dbSNP and Humsavar for MIR1976 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs113855506 -- 26,553,931(+) TAGCT(C/T)AATGA intron-variant, upstream-variant-2KB
rs139221118 -- 26,554,160(+) AACAC(C/G)ATCAC intron-variant, upstream-variant-2KB
rs140879798 -- 26,552,730(+) GATCC(A/G)CCTGC intron-variant, upstream-variant-2KB
rs141051128 -- 26,554,627(+) GACCA(C/T)GAGAA downstream-variant-500B, reference, synonymous-codon
rs141533618 -- 26,554,682(+) AGGTC(A/G)TCAAC downstream-variant-500B, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for MIR1976 Gene

Variant ID Type Subtype PubMed ID
nsv526179 CNV gain 19592680
nsv545908 CNV loss 21841781

Relevant External Links for MIR1976 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1976

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1976 Gene

Disorders for MIR1976 Gene

Relevant External Links for MIR1976

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1976

No disorders were found for MIR1976 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1976 Gene

Publications for MIR1976 Gene

  1. Identification of new microRNA genes and aberrant microRNA profiles in childhood acute lymphoblastic leukemia. (PMID: 18923441) Schotte D. … den Boer M.L. (Leukemia 2009) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1976 Gene

Sources for MIR1976 Gene

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