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Aliases for MIR1973 Gene

Subcategory (RNA class) for MIR1973 Gene

miRNA

Quality Score for this RNA gene is

2

Aliases for MIR1973 Gene

  • MicroRNA 1973 2 3
  • Hsa-Mir-1973 3
  • Mir-1973 3

External Ids for MIR1973 Gene

Previous GeneCards Identifiers for MIR1973 Gene

  • GC00U923182
  • GC04P117220

Summaries for MIR1973 Gene

Entrez Gene Summary for MIR1973 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1973 Gene

MIR1973 (MicroRNA 1973) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR1973 include renal cell carcinoma, papillary.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1973 Gene

Genomics for MIR1973 Gene

Genomic Location for MIR1973 Gene

Chromosome:
4
Start:
116,299,725 bp from pter
End:
116,299,768 bp from pter
Size:
44 bases
Orientation:
Plus strand

Genomic View for MIR1973 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR1973 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1973 Gene

No data available for Regulatory Elements for MIR1973 Gene

Proteins for MIR1973 Gene

Post-translational modifications for MIR1973 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1973 Gene

Domains & Families for MIR1973 Gene

Gene Families for MIR1973 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1973: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1973 Gene

Function for MIR1973 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1973 Gene

Localization for MIR1973 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1973 Gene

Pathways & Interactions for MIR1973 Gene

SuperPathways for MIR1973 Gene

No Data Available

Interacting Proteins for MIR1973 Gene

Gene Ontology (GO) - Biological Process for MIR1973 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1973 Gene

Drugs & Compounds for MIR1973 Gene

No Compound Related Data Available

Transcripts for MIR1973 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1973 Gene

No ASD Table

Relevant External Links for MIR1973 Gene

GeneLoc Exon Structure for
MIR1973
ECgene alternative splicing isoforms for
MIR1973

No data available for mRNA/cDNA for MIR1973 Gene

Expression for MIR1973 Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR1973 Gene

Orthologs for MIR1973 Gene

No data available for Orthologs and Evolution for MIR1973 Gene

Paralogs for MIR1973 Gene

No data available for Paralogs for MIR1973 Gene

Variants for MIR1973 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1973 Gene

Variant ID Type Subtype PubMed ID
nsv879753 CNV Loss 21882294
nsv879788 CNV Gain 21882294

Relevant External Links for MIR1973 Gene

HapMap Linkage Disequilibrium report
MIR1973

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR1973 Gene

Disorders for MIR1973 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR1973 Gene - From: DISEASES

Disorder Aliases PubMed IDs
renal cell carcinoma, papillary
  • renal cell carcinoma
- elite association

Relevant External Links for MIR1973

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1973
genes like me logo Genes that share disorders with MIR1973: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR1973 Gene

Publications for MIR1973 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 67
  2. Identification of new microRNA genes and aberrant microRNA profiles in childhood acute lymphoblastic leukemia. (PMID: 18923441) Schotte D. … den Boer M.L. (Leukemia 2009) 67
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 67

Products for MIR1973 Gene

Sources for MIR1973 Gene

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