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Aliases for MIR1972-2 Gene

Subcategory (RNA class) for MIR1972-2 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1972-2 Gene

  • MicroRNA 1972-2 2 3
  • Hsa-Mir-1972-2 3

External Ids for MIR1972-2 Gene

Summaries for MIR1972-2 Gene

Entrez Gene Summary for MIR1972-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1972-2 Gene

MIR1972-2 (MicroRNA 1972-2) is a RNA Gene, and belongs to miRNA RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1972-2 Gene

Genomics for MIR1972-2 Gene

Genomic Location for MIR1972-2 Gene

Start:
70,030,346 bp from pter
End:
70,030,422 bp from pter
Size:
77 bases
Orientation:
Plus strand

Genomic View for MIR1972-2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR1972-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1972-2 Gene

No data available for Regulatory Elements for MIR1972-2 Gene

Proteins for MIR1972-2 Gene

Post-translational modifications for MIR1972-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1972-2 Gene

Domains for MIR1972-2 Gene

Gene Families for MIR1972-2 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR1972-2: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR1972-2 Gene

Function for MIR1972-2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR1972-2 Gene

Localization for MIR1972-2 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR1972-2 Gene

Pathways for MIR1972-2 Gene

SuperPathways for MIR1972-2 Gene

No Data Available

Interacting Proteins for MIR1972-2 Gene

Gene Ontology (GO) - Biological Process for MIR1972-2 Gene

None

No data available for Pathways by source for MIR1972-2 Gene

Transcripts for MIR1972-2 Gene

mRNA/cDNA for MIR1972-2 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1972-2 Gene

No ASD Table

Relevant External Links for MIR1972-2 Gene

GeneLoc Exon Structure for
MIR1972-2
ECgene alternative splicing isoforms for
MIR1972-2

Expression for MIR1972-2 Gene

mRNA expression in normal human tissues for MIR1972-2 Gene

genes like me logo Genes that share expressions with MIR1972-2: view

Orthologs for MIR1972-2 Gene

Evolution for MIR1972-2 Gene

ENSEMBL:
Gene Tree for MIR1972-2 (if available)
TreeFam:
Gene Tree for MIR1972-2 (if available)

No data available for Orthologs for MIR1972-2 Gene

Paralogs for MIR1972-2 Gene

No data available for Paralogs for MIR1972-2 Gene

Variants for MIR1972-2 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1972-2 Gene

Variant ID Type Subtype PubMed ID
dgv895e1 CNV Complex 17122850
nsv1853 CNV Loss 18451855
dgv2892n71 CNV Gain 21882294
dgv2893n71 CNV Gain 21882294
dgv485n67 CNV Loss 20364138
esv2714669 CNV Deletion 23290073
nsv428328 CNV Gain+Loss 18775914
dgv2894n71 CNV Gain 21882294
dgv2895n71 CNV Loss 21882294
nsv436059 CNV Insertion 17901297
esv2657437 CNV Deletion 23128226
dgv2896n71 CNV Gain 21882294
dgv2897n71 CNV Gain 21882294
nsv827719 CNV Gain 20364138
nsv833269 CNV Loss 17160897
esv987821 CNV Gain 20482838
esv25951 CNV Loss 19812545
nsv9453 CNV Loss 18304495
nsv827721 CNV Loss 20364138
nsv827722 CNV Loss 20364138
nsv827723 CNV Loss 20364138
nsv906845 CNV Gain 21882294
nsv820087 CNV Loss 19587683
essv1325 CNV CNV 17122850
nsv517743 CNV Loss 19592680

Relevant External Links for MIR1972-2 Gene

HapMap Linkage Disequilibrium report
MIR1972-2

No data available for Sequence variations from dbSNP and Humsavar for MIR1972-2 Gene

Disorders for MIR1972-2 Gene

No disorders were found for MIR1972-2 Gene.

No data available for UniProtKB/Swiss-Prot for MIR1972-2 Gene

Publications for MIR1972-2 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Identification of new microRNA genes and aberrant microRNA profiles in childhood acute lymphoblastic leukemia. (PMID: 18923441) Schotte D. … den Boer M.L. (Leukemia 2009) 3
  3. Large-scale genotyping identifies 41 new loci associated with breast cancer risk. (PMID: 23535729) Michailidou K. … Easton D.F. (Nat. Genet. 2013) 3
  4. Genome-wide association studies identify four ER negative-specific breast cancer risk loci. (PMID: 23535733) Garcia-Closas M. … Kraft P. (Nat. Genet. 2013) 3

Products for MIR1972-2 Gene

Sources for MIR1972-2 Gene

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