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Aliases for MIR197 Gene

Subcategory (RNA class) for MIR197 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR197 Gene

  • MicroRNA 197 2 3 5
  • Hsa-Mir-197 3
  • MiRNA197 3
  • MiR-197 3
  • MIRN197 3

External Ids for MIR197 Gene

Previous HGNC Symbols for MIR197 Gene

  • MIRN197

Previous GeneCards Identifiers for MIR197 Gene

  • GC01P109943
  • GC01P110141
  • GC01P109598

Summaries for MIR197 Gene

Entrez Gene Summary for MIR197 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR197 Gene

MIR197 (MicroRNA 197) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR197 include Auriculocondylar Syndrome 1. Among its related pathways are Peptide ligand-binding receptors and Chaperonin-mediated protein folding.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR197 Gene

Genomics for MIR197 Gene

Regulatory Elements for MIR197 Gene

Enhancers for MIR197 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G109643 1.4 Ensembl ENCODE dbSUPER 11.7 +44.7 44681 0.7 HDGF HDAC1 RB1 ARID4B ZNF2 RAD21 ZEB1 GLIS2 SCRT2 ZNF143 GSTM4 GNAT2 AMPD2 GNAI3 MIR197 ENSG00000225113 RNU6V GSTM3 GC01M109631 RPL7P8
GH01G109761 1.5 Ensembl ENCODE dbSUPER 10.2 +165.9 165936 5.9 MLX ZFP64 ARID4B DMAP1 SLC30A9 ZNF766 FOS SP5 JUNB ZNF592 GSTM3 AHCYL1 ENSG00000228703 AMPD2 ENSG00000254942 GPR61 GNAT2 GNAI3 CSF1 MIR197
GH01G109773 1.5 Ensembl ENCODE dbSUPER 10.1 +174.9 174908 0.4 HDGF ATF1 ARNT ARID4B SIN3A GATA2 ZNF143 KLF13 DEK ZNF263 AHCYL1 ENSG00000228703 AMPD2 GSTM3 CSF1 GNAI3 ENSG00000254942 GPR61 MIR197 UBL4B
GH01G109776 1.4 Ensembl ENCODE dbSUPER 10.1 +178.4 178443 1.8 HDGF ATF1 FOXA2 ARID4B ZNF2 ZNF48 GLIS2 ZNF143 FOS ZMIZ1 GSTM3 AHCYL1 ENSG00000228703 AMPD2 CSF1 GNAI3 ENSG00000254942 GPR61 MIR197 ENSG00000235005
GH01G109782 1.3 Ensembl ENCODE dbSUPER 9.6 +184.2 184208 1.8 TBP PKNOX1 RAD21 BRCA1 RFX5 RCOR1 DEK SMARCC1 CEBPB ELF1 GSTM3 AHCYL1 CSF1 ENSG00000228703 AMPD2 ENSG00000235005 STRIP1 MIR197 PIR57260 EPS8L3
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR197 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR197 Gene

Chromosome:
1
Start:
109,598,893 bp from pter
End:
109,598,967 bp from pter
Size:
75 bases
Orientation:
Plus strand

Genomic View for MIR197 Gene

Genes around MIR197 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR197 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR197 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR197 Gene

Proteins for MIR197 Gene

Post-translational modifications for MIR197 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR197 Gene

Domains & Families for MIR197 Gene

Gene Families for MIR197 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR197: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR197 Gene

Function for MIR197 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR197 Gene

Localization for MIR197 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR197 Gene

Pathways & Interactions for MIR197 Gene

genes like me logo Genes that share pathways with MIR197: view

Interacting Proteins for MIR197 Gene

Gene Ontology (GO) - Biological Process for MIR197 Gene

None

No data available for SIGNOR curated interactions for MIR197 Gene

Drugs & Compounds for MIR197 Gene

No Compound Related Data Available

Transcripts for MIR197 Gene

mRNA/cDNA for MIR197 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR197 Gene

No ASD Table

Relevant External Links for MIR197 Gene

GeneLoc Exon Structure for
MIR197
ECgene alternative splicing isoforms for
MIR197

Expression for MIR197 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR197 Gene:

MIR197
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR197 Gene

Orthologs for MIR197 Gene

Evolution for MIR197 Gene

ENSEMBL:
Gene Tree for MIR197 (if available)
TreeFam:
Gene Tree for MIR197 (if available)

No data available for Orthologs for MIR197 Gene

Paralogs for MIR197 Gene

No data available for Paralogs for MIR197 Gene

Variants for MIR197 Gene

Sequence variations from dbSNP and Humsavar for MIR197 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000805828 -- 109,597,357(+) CTCGG(A/G)AGGCT upstream-variant-2KB
rs1001122869 -- 109,597,585(+) GACTT(-/A)AAAGT upstream-variant-2KB
rs1001424890 -- 109,597,455(+) GTCTG(-/T)TTTTT upstream-variant-2KB
rs1003082552 -- 109,598,785(+) TCTGA(A/C)CTCAC upstream-variant-2KB
rs1003997269 -- 109,598,984(+) GTCTA(C/G/T)GGCAC downstream-variant-500B

Relevant External Links for MIR197 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR197

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR197 Gene

Disorders for MIR197 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR197 Gene - From: GeneCards

Disorder Aliases PubMed IDs
auriculocondylar syndrome 1
  • acs
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR197

Genetic Association Database (GAD)
MIR197
Human Genome Epidemiology (HuGE) Navigator
MIR197
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR197
genes like me logo Genes that share disorders with MIR197: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR197 Gene

Publications for MIR197 Gene

  1. Novel genetic variants in miR-191 gene and familial ovarian cancer. (PMID: 20167074) Shen J. … Zhao H. (BMC Cancer 2010) 3 46 64
  2. EBVa89BARTa896a893p and cellular microRNAa89197 compromise the immune defense of host cells in EBVa89positive Burkitt lymphoma. (PMID: 28259992) Zhang Y.M. … Zhao H.P. (Mol Med Rep 2017) 3 64
  3. Micro RNAs mir-106a, mir-122 and mir-197 are increased in severe acute viral hepatitis with coagulopathy. (PMID: 26352910) Weseslindtner L. … Odenthal M. (Liver Int. 2016) 3 64
  4. miR-197: A novel biomarker for cancers. (PMID: 27320730) Wang D.D. … Tang J.H. (Gene 2016) 3 64
  5. LINC00312 inhibits the migration and invasion of bladder cancer cells by targeting miR-197-3p. (PMID: 27631965) Wang Y.Y. … Meng J.S. (Tumour Biol. 2016) 3 64

Products for MIR197 Gene

Sources for MIR197 Gene

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