Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR197 Gene

Subcategory (RNA class) for MIR197 Gene


Quality Score for this RNA gene is


Aliases for MIR197 Gene

  • MicroRNA 197 2 3 5
  • Hsa-Mir-197 3
  • MiRNA197 3
  • MiR-197 3
  • MIRN197 3

External Ids for MIR197 Gene

Previous HGNC Symbols for MIR197 Gene

  • MIRN197

Previous GeneCards Identifiers for MIR197 Gene

  • GC01P109943
  • GC01P110141

Summaries for MIR197 Gene

Entrez Gene Summary for MIR197 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR197 Gene

MIR197 (MicroRNA 197) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR197 Gene

Genomics for MIR197 Gene

Regulatory Elements for MIR197 Gene

Enhancers for MIR197 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR197 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR197 Gene

109,598,893 bp from pter
109,598,967 bp from pter
75 bases
Plus strand

Genomic View for MIR197 Gene

Genes around MIR197 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR197 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR197 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR197 Gene

Proteins for MIR197 Gene

Post-translational modifications for MIR197 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR197 Gene

Domains & Families for MIR197 Gene

Gene Families for MIR197 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR197: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR197 Gene

Function for MIR197 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR197 Gene

Localization for MIR197 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR197 Gene

Pathways & Interactions for MIR197 Gene

SuperPathways for MIR197 Gene

No Data Available

Interacting Proteins for MIR197 Gene

Gene Ontology (GO) - Biological Process for MIR197 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR197 Gene

Drugs & Compounds for MIR197 Gene

No Compound Related Data Available

Transcripts for MIR197 Gene

mRNA/cDNA for MIR197 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR197 Gene

No ASD Table

Relevant External Links for MIR197 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR197 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR197 Gene

Orthologs for MIR197 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR197 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-197 36
  • 91 (a)
(Canis familiaris)
Mammalia cfa-mir-197 36
  • 100 (a)
(Pan troglodytes)
Mammalia ptr-mir-197 36
  • 100 (a)
Species with no ortholog for MIR197:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR197 Gene

Gene Tree for MIR197 (if available)
Gene Tree for MIR197 (if available)

Paralogs for MIR197 Gene

No data available for Paralogs for MIR197 Gene

Variants for MIR197 Gene

Sequence variations from dbSNP and Humsavar for MIR197 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs505303 -- 109,598,355(+) CCAAC(C/T)AGCTA upstream-variant-2KB
rs1889470 -- 109,598,799(-) ATGAA(A/C/G/T)ACATT upstream-variant-2KB
rs34028288 -- 109,599,459(+) GACTA(-/T)TTTTA downstream-variant-500B
rs17648684 -- 109,598,565(+) TTCAA(C/T)GTAGT upstream-variant-2KB
rs17024132 -- 109,597,477(+) TTTTA(A/T)AGTCA upstream-variant-2KB

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for MIR197 Gene

Disorders for MIR197 Gene

Relevant External Links for MIR197

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR197 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR197 Gene

Publications for MIR197 Gene

  1. Novel genetic variants in miR-191 gene and familial ovarian cancer. (PMID: 20167074) Shen J. … Zhao H. (BMC Cancer 2010) 3 48 67
  2. STAT6 silencing up-regulates cholesterol synthesis via miR-197/FOXJ2 axis and induces ER stress-mediated apoptosis in lung cancer cells. (PMID: 25451482) Dubey R. … Saini N. (Biochim. Biophys. Acta 2015) 3
  3. miR-137 and miR-197 Induce Apoptosis and Suppress Tumorigenicity by Targeting MCL-1 in Multiple Myeloma. (PMID: 25724519) Yang Y. … Chang H. (Clin. Cancer Res. 2015) 3
  4. MiR-197 induces Taxol resistance in human ovarian cancer cells by regulating NLK. (PMID: 25833695) Zou D. … Zhou Q. (Tumour Biol. 2015) 3
  5. The oncomiR miR-197 is a novel prognostic indicator for non-small cell lung cancer patients. (PMID: 25867273) Mavridis K. … Scorilas A. (Br. J. Cancer 2015) 3

Products for MIR197 Gene

Sources for MIR197 Gene