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Aliases for MIR196A2 Gene

Subcategory (RNA class) for MIR196A2 Gene


Quality Score for this RNA gene is


Aliases for MIR196A2 Gene

  • MicroRNA 196a-2 2 3
  • MicroRNA 196-2 2 3
  • MIRN196A2 3 6
  • Hsa-Mir-196a-2 3
  • Hsa-Mir-196-2 3
  • MIRN196-2 3

External Ids for MIR196A2 Gene

ORGUL Members for MIR196A2 Gene

Previous HGNC Symbols for MIR196A2 Gene

  • MIRN196-2
  • MIRN196A2

Previous GeneCards Identifiers for MIR196A2 Gene

  • GC12P052675
  • GC12P054385

Summaries for MIR196A2 Gene

Entrez Gene Summary for MIR196A2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR196A2 Gene

MIR196A2 (MicroRNA 196a-2) is an RNA Gene, and is affiliated with the undefined RNA class. Diseases associated with MIR196A2 include keloids and pancreatic ductal adenocarcinoma.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR196A2 Gene

Genomics for MIR196A2 Gene

Genomic Location for MIR196A2 Gene

53,991,738 bp from pter
53,991,847 bp from pter
110 bases
Plus strand

Genomic View for MIR196A2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR196A2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR196A2 Gene

No data available for Regulatory Elements for MIR196A2 Gene

Proteins for MIR196A2 Gene

Post-translational modifications for MIR196A2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR196A2 Gene

Domains for MIR196A2 Gene

Gene Families for MIR196A2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR196A2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR196A2 Gene

Function for MIR196A2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR196A2 Gene

Localization for MIR196A2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR196A2 Gene

Pathways for MIR196A2 Gene

SuperPathways for MIR196A2 Gene

No Data Available

Interacting Proteins for MIR196A2 Gene

Gene Ontology (GO) - Biological Process for MIR196A2 Gene


No data available for Pathways by source for MIR196A2 Gene

Transcripts for MIR196A2 Gene

mRNA/cDNA for MIR196A2 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR196A2 Gene

No ASD Table

Relevant External Links for MIR196A2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR196A2 Gene

mRNA expression in normal human tissues for MIR196A2 Gene

genes like me logo Genes that share expressions with MIR196A2: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR196A2 Gene

Orthologs for MIR196A2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR196A2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-196a-2 36
  • 99 (a)
(Canis familiaris)
Mammalia cfa-mir-196a-2 36
  • 100 (a)
(Mus musculus)
Mammalia Mir196a-2 36
  • 99 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-196a 36
  • 91 (a)
(Pan troglodytes)
Mammalia ptr-mir-196a-2 36
  • 100 (a)
(Gallus gallus)
Aves gga-mir-196-3 36
  • 84 (a)
(Anolis carolinensis)
Reptilia aca-mir-196a-2 36
  • 82 (a)
(Danio rerio)
Actinopterygii mir196a-1 36
  • 78 (a)
mir196c 36
  • 75 (a)
mir196d 36
  • 74 (a)
Species with no ortholog for MIR196A2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR196A2 Gene

Gene Tree for MIR196A2 (if available)
Gene Tree for MIR196A2 (if available)

Paralogs for MIR196A2 Gene

No data available for Paralogs for MIR196A2 Gene

Variants for MIR196A2 Gene

Sequence variations from dbSNP and Humsavar for MIR196A2 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs577249078 -- 53,992,061(+) CTGGG(A/C)CCAGC downstream-variant-500B
rs575701744 -- 53,991,148(+) GTGGG(-/GGA)GGAGG upstream-variant-2KB
rs571980468 -- 53,990,965(+) CGCTG(A/G)CAGCG upstream-variant-2KB
rs570838070 -- 53,991,845(+) TCGAG(G/T)GCCCC nc-transcript-variant
rs570676598 -- 53,991,258(+) GTAAC(A/G)TTTTG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR196A2 Gene

Variant ID Type Subtype PubMed ID
nsv826379 CNV Gain 20364138
nsv899100 CNV Loss 21882294
dgv512e1 CNV Complex 17122850
nsv428282 CNV Gain 18775914

Relevant External Links for MIR196A2 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR196A2 Gene

Disorders for MIR196A2 Gene

Relevant External Links for MIR196A2

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with MIR196A2: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for MIR196A2 Gene

Publications for MIR196A2 Gene

  1. Association between common genetic variants in pre-microRNAs and gastric cancer risk in Japanese population. (PMID: 21073609) Okubo M. … Hirata I. (Helicobacter 2010) 3 48
  2. Functional variant in microRNA-196a2 contributes to the susceptibility of congenital heart disease in a Chinese population. (PMID: 19514064) Xu J. … Chen Y. (Hum. Mutat. 2009) 3 48
  3. Evaluation of SNPs in miR-146a, miR196a2 and miR-499 as low-penetrance alleles in German and Italian familial breast cancer cases. (PMID: 19847796) Catucci I. … Peterlongo P. (Hum. Mutat. 2010) 3 48
  4. Common genetic variants in pre-microRNAs are associated with risk of coal workers' pneumoconiosis. (PMID: 19881472) Wang M. … Ni C. (J. Hum. Genet. 2010) 3 48
  5. A polymorphism of microRNA196a genome region was associated with decreased risk of glioma in Chinese population. (PMID: 20229273) Dou T. … Lu D. (J. Cancer Res. Clin. Oncol. 2010) 3 48

Products for MIR196A2 Gene

Sources for MIR196A2 Gene

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