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Aliases for MIR194-2 Gene

Subcategory (RNA class) for MIR194-2 Gene

lncRNA

Quality Score for this RNA gene is

13

Aliases for MIR194-2 Gene

  • MicroRNA 194-2 2 3
  • MIRN194-2 3 6
  • Hsa-Mir-194-2 3

External Ids for MIR194-2 Gene

ORGUL Members for MIR194-2 Gene

Previous Symbols for MIR194-2 Gene

  • MIRN194-2

Summaries for MIR194-2 Gene

Entrez Gene Summary for MIR194-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR194-2 Gene

MIR194-2 (MicroRNA 194-2) is a RNA Gene, and belongs to lncRNA RNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR194-2 Gene

Genomics for MIR194-2 Gene

Genomic Location for MIR194-2 Gene

Start:
64,891,355 bp from pter
End:
64,891,439 bp from pter
Size:
85 bases
Orientation:
Minus strand

Genomic View for MIR194-2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR194-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR194-2 Gene

No data available for Regulatory Elements for MIR194-2 Gene

Proteins for MIR194-2 Gene

Post-translational modifications for MIR194-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR194-2 Gene

Domains for MIR194-2 Gene

Gene Families for MIR194-2 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR194-2: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR194-2 Gene

Function for MIR194-2 Gene

miRNA for MIR194-2 Gene

miRTarBase miRNAs that target MIR194-2

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for MIR194-2 Gene

Localization for MIR194-2 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR194-2 Gene

Pathways for MIR194-2 Gene

SuperPathways for MIR194-2 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR194-2: view

Pathways by source for MIR194-2 Gene

1 KEGG pathway for MIR194-2 Gene

Interacting Proteins for MIR194-2 Gene

Gene Ontology (GO) - Biological Process for MIR194-2 Gene

None

Transcripts for MIR194-2 Gene

mRNA/cDNA for MIR194-2 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR194-2 Gene

No ASD Table

Relevant External Links for MIR194-2 Gene

GeneLoc Exon Structure for
MIR194-2
ECgene alternative splicing isoforms for
MIR194-2

Expression for MIR194-2 Gene

mRNA expression in normal human tissues for MIR194-2 Gene

mRNA differential expression in normal tissues according to GTEx for MIR194-2 Gene

This gene is overexpressed in Colon - Transverse (20.0) and Small Intestine - Terminal Ileum (18.2).
genes like me logo Genes that share expressions with MIR194-2: view

Orthologs for MIR194-2 Gene

Evolution for MIR194-2 Gene

ENSEMBL:
Gene Tree for MIR194-2 (if available)
TreeFam:
Gene Tree for MIR194-2 (if available)

No data available for Orthologs for MIR194-2 Gene

Paralogs for MIR194-2 Gene

No data available for Paralogs for MIR194-2 Gene

Variants for MIR194-2 Gene

Sequence variations from dbSNP and Humsavar for MIR194-2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs138234709 -- 64,893,378(+) AGGGC(G/T)GCAGG upstream-variant-2KB
rs527668500 -- 64,893,381(+) GCGGC(A/G)GGGGT upstream-variant-2KB
rs531754300 -- 64,893,290(+) CACCC(C/T)ATGGC upstream-variant-2KB
rs541278935 -- 64,893,258(+) CAAGG(C/T)ACAGA upstream-variant-2KB
rs548123034 -- 64,893,420(+) GTGCC(A/G)GGCTG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR194-2 Gene

Variant ID Type Subtype PubMed ID
nsv528506 CNV Loss 19592680
dgv1171n71 CNV Loss 21882294
dgv1173n71 CNV Loss 21882294
nsv360 CNV Loss 18451855
nsv526181 CNV Gain 19592680

Relevant External Links for MIR194-2 Gene

HapMap Linkage Disequilibrium report
MIR194-2

Disorders for MIR194-2 Gene

No disorders were found for MIR194-2 Gene.

No data available for UniProtKB/Swiss-Prot for MIR194-2 Gene

Publications for MIR194-2 Gene

  1. New microRNAs from mouse and human. (PMID: 12554859) Lagos-Quintana M. … Tuschl T. (RNA 2003) 3
  2. Reduced accumulation of specific microRNAs in colorectal neoplasia. (PMID: 14573789) Michael M.Z. … James R.J. (Mol. Cancer Res. 2003) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  5. Differentially expressed microRNAs and affected biological pathways revealed by modulated modularity clustering (MMC) analysis of human preeclamptic and IUGR placentas. (PMID: 23639576) Guo L. … Piedrahita J.A. (Placenta 2013) 3

Products for MIR194-2 Gene

Sources for MIR194-2 Gene

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