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Aliases for MIR194-1 Gene

Subcategory (RNA class) for MIR194-1 Gene


Quality Score for this RNA gene is


Aliases for MIR194-1 Gene

  • MicroRNA 194-1 2 3 5
  • Hsa-Mir-194-1 3
  • Mir-194-1 3
  • MIRN194-1 3

External Ids for MIR194-1 Gene

Previous HGNC Symbols for MIR194-1 Gene

  • MIRN194-1

Previous GeneCards Identifiers for MIR194-1 Gene

  • GC01M218360
  • GC01M220292
  • GC01M220293
  • GC01M220295

Summaries for MIR194-1 Gene

Entrez Gene Summary for MIR194-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR194-1 Gene

MIR194-1 (MicroRNA 194-1) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR194-1 Gene

Genomics for MIR194-1 Gene

Regulatory Elements for MIR194-1 Gene

Enhancers for MIR194-1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR194-1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR194-1 Gene

220,118,157 bp from pter
220,118,241 bp from pter
85 bases
Minus strand

Genomic View for MIR194-1 Gene

Genes around MIR194-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR194-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR194-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR194-1 Gene

ORGUL Member Location for MIR194-1 Gene

ORGUL Member Location for MIR194-1 gene

Proteins for MIR194-1 Gene

Post-translational modifications for MIR194-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR194-1 Gene

Domains & Families for MIR194-1 Gene

Gene Families for MIR194-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR194-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR194-1 Gene

Function for MIR194-1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR194-1 Gene

Localization for MIR194-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR194-1 Gene

Pathways & Interactions for MIR194-1 Gene

SuperPathways for MIR194-1 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR194-1: view

Pathways by source for MIR194-1 Gene

1 KEGG pathway for MIR194-1 Gene

Interacting Proteins for MIR194-1 Gene

Gene Ontology (GO) - Biological Process for MIR194-1 Gene


No data available for SIGNOR curated interactions for MIR194-1 Gene

Drugs & Compounds for MIR194-1 Gene

No Compound Related Data Available

Transcripts for MIR194-1 Gene

mRNA/cDNA for MIR194-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR194-1 Gene

No ASD Table

Relevant External Links for MIR194-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR194-1 Gene

mRNA expression in normal human tissues for MIR194-1 Gene

genes like me logo Genes that share expression patterns with MIR194-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR194-1 Gene

Orthologs for MIR194-1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR194-1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-194-1 36
  • 77 (a)
(Canis familiaris)
Mammalia cfa-mir-194 36
  • 95 (a)
(Mus musculus)
Mammalia Mir194-1 36
  • 79 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-194-1 36
  • 69 (a)
oan-mir-194-1 36
  • 69 (a)
(Pan troglodytes)
Mammalia ptr-mir-194 36
  • 100 (a)
(Gallus gallus)
Aves gga-mir-194 36
  • 80 (a)
(Anolis carolinensis)
Reptilia aca-mir-194-1 36
  • 65 (a)
Species with no ortholog for MIR194-1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR194-1 Gene

Gene Tree for MIR194-1 (if available)
Gene Tree for MIR194-1 (if available)

Paralogs for MIR194-1 Gene

No data available for Paralogs for MIR194-1 Gene

Variants for MIR194-1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR194-1 Gene

Variant ID Type Subtype PubMed ID
nsv832636 CNV Loss 17160897

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Variation tolerance and Relevant External Links for MIR194-1 Gene

Disorders for MIR194-1 Gene

Relevant External Links for MIR194-1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR194-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR194-1 Gene

Publications for MIR194-1 Gene

  1. miR-194 regulated AGK and inhibited cell proliferation of oral squamous cell carcinoma by reducing PI3K-Akt-FoxO3a signaling. (PMID: 25960215) Chi H. (Biomed. Pharmacother. 2015) 3 67
  2. miR-194 targets RBX1 gene to modulate proliferation and migration of gastric cancer cells. (PMID: 25412959) Chen X. … Zhao G. (Tumour Biol. 2015) 3
  3. MiR-194, commonly repressed in colorectal cancer, suppresses tumor growth by regulating the MAP4K4/c-Jun/MDM2 signaling pathway. (PMID: 25602366) Wang B. … Wang S. (Cell Cycle 2015) 3
  4. MiRNA-194 Regulates Palmitic Acid-Induced Toll-Like Receptor 4 Inflammatory Responses in THP-1 Cells. (PMID: 25984739) Tian H. … Yuan D. (Nutrients 2015) 3
  5. miR-194 as a predictor for adenoma recurrence in patients with advanced colorectal adenoma after polypectomy. (PMID: 24691499) Wang Z.H. … Fang J.Y. (Cancer Prev Res (Phila) 2014) 3

Products for MIR194-1 Gene

Sources for MIR194-1 Gene