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Aliases for MIR193B Gene

Subcategory (RNA class) for MIR193B Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR193B Gene

  • MicroRNA 193b 2 3
  • Hsa-Mir-193b 3
  • MIRN193B 3

External Ids for MIR193B Gene

ORGUL Members for MIR193B Gene

Previous HGNC Symbols for MIR193B Gene

  • MIRN193B

Previous GeneCards Identifiers for MIR193B Gene

  • GC16P014306
  • GC16P014397

Summaries for MIR193B Gene

Entrez Gene Summary for MIR193B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR193B Gene

MIR193B (MicroRNA 193b) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR193B include multiple myeloma. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR193B Gene

Genomics for MIR193B Gene

Genomic Location for MIR193B Gene

Start:
14,303,967 bp from pter
End:
14,304,049 bp from pter
Size:
83 bases
Orientation:
Plus strand

Genomic View for MIR193B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR193B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR193B Gene

No data available for Regulatory Elements for MIR193B Gene

Proteins for MIR193B Gene

Post-translational modifications for MIR193B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR193B Gene

Domains for MIR193B Gene

Gene Families for MIR193B Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR193B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR193B Gene

Function for MIR193B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR193B Gene

Localization for MIR193B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR193B Gene

Pathways for MIR193B Gene

SuperPathways for MIR193B Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR193B: view

Pathways by source for MIR193B Gene

1 KEGG pathway for MIR193B Gene

Interacting Proteins for MIR193B Gene

Gene Ontology (GO) - Biological Process for MIR193B Gene

None

Transcripts for MIR193B Gene

mRNA/cDNA for MIR193B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MIR193B

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR193B Gene

No ASD Table

Relevant External Links for MIR193B Gene

GeneLoc Exon Structure for
MIR193B
ECgene alternative splicing isoforms for
MIR193B

Expression for MIR193B Gene

mRNA expression in normal human tissues for MIR193B Gene

genes like me logo Genes that share expressions with MIR193B: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR193B Gene

Orthologs for MIR193B Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR193B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-193b 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-193b 36
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-193b 36
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir193b 36
  • 90 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-193b 36
  • 77 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-193 36
  • 76 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-193b 36
  • 87 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-193b 36
  • 74 (a)
OneToOne
Species with no ortholog for MIR193B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR193B Gene

ENSEMBL:
Gene Tree for MIR193B (if available)
TreeFam:
Gene Tree for MIR193B (if available)

Paralogs for MIR193B Gene

No data available for Paralogs for MIR193B Gene

Variants for MIR193B Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR193B Gene

Variant ID Type Subtype PubMed ID
nsv905355 CNV Loss 21882294

Relevant External Links for MIR193B Gene

HapMap Linkage Disequilibrium report
MIR193B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR193B Gene

Disorders for MIR193B Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for MIR193B Gene including...

Search for MIR193B Gene in MalaCards »

Relevant External Links for MIR193B

Human Genome Epidemiology (HuGE) Navigator
MIR193B
genes like me logo Genes that share disorders with MIR193B: view

No data available for UniProtKB/Swiss-Prot for MIR193B Gene

Publications for MIR193B Gene

  1. Identification of hundreds of conserved and nonconserved human microRNAs. (PMID: 15965474) Bentwich I. … Bentwich Z. (Nat. Genet. 2005) 3
  2. Identification of clustered microRNAs using an ab initio prediction method. (PMID: 16274478) Sewer A. … Zavolan M. (BMC Bioinformatics 2005) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  5. Patterns of known and novel small RNAs in human cervical cancer. (PMID: 17616659) Lui W.O. … Fire A. (Cancer Res. 2007) 3

Products for MIR193B Gene

Sources for MIR193B Gene

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