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MIR193A Gene(RNA Gene)

MicroRNA 193a

GCID:
GC17P031559
GIFtS:
17
Genes Participants
UDN Logo

Aliases for MIR193A Gene

Subcategory (RNA class) for MIR193A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR193A Gene

  • MicroRNA 193a 2 3 5
  • MicroRNA 193 2
  • Hsa-Mir-193a 3
  • Hsa-Mir-193 3
  • Mir-193a 3
  • MIRN193A 3
  • MIRN193 3

External Ids for MIR193A Gene

ORGUL Members for MIR193A Gene

Previous HGNC Symbols for MIR193A Gene

  • MIRN193
  • MIRN193A

Previous GeneCards Identifiers for MIR193A Gene

  • GC17P026914
  • GC17P029887

Summaries for MIR193A Gene

Entrez Gene Summary for MIR193A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR193A Gene

MIR193A (MicroRNA 193a) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR193A Gene

Genomics for MIR193A Gene

Products:

  1. Regulatory Element

Regulatory Elements for MIR193A Gene

Enhancers for MIR193A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17F031592 1.5 FANTOM5 Ensembl ENCODE 12.1 +36.3 36284 6.7 TBP PKNOX1 SIN3A ZNF48 RAD21 FOS JUNB CEBPB KAT8 IKZF1 RAB11FIP4 MIR193A RNU6ATAC7P MIR4724 RNF135 CRLF3 EVI2A ENSG00000266877 GC17M031638 PIR51917
GH17F031578 1.4 FANTOM5 Ensembl ENCODE 12.6 +20.9 20905 4.2 BCOR TBP ZNF146 CBX3 JUN ZMYM3 SIN3A ZIC2 RAD21 RFX5 MIR193A MIR4724 RAB11FIP4 EVI2A EVI2B ENSG00000266877 GC17M031575
GH17F031680 1.3 FANTOM5 Ensembl ENCODE 10.9 +120.2 120213 0.4 ZMYM3 YBX1 BMI1 RELA EED ETV6 CREM SRF MTA2 TRIM22 MIR193A C17orf75 EVI2A EVI2B RHOT1 GC17M031689 GC17M031638 PIR51917
GH17F031537 1 Ensembl ENCODE 12.2 -22.0 -21995 1.2 CTCF PKNOX1 MXI1 TBL1XR1 EBF1 ZIC2 CREM CHD2 ZNF263 MAZ RAB11FIP4 MIR193A MIR4724 RNU6ATAC7P ENSG00000278977 GC17P031541
GH17F031535 0.9 Ensembl ENCODE 12.2 -24.2 -24190 0.4 HDGF CTCF PKNOX1 MAZ TBL1XR1 BHLHE40 EP300 EED IKZF1 MYB RAB11FIP4 MIR193A MIR4724 RNU6ATAC7P ENSG00000278977 GC17P031541
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR193A on UCSC Golden Path with GeneCards custom track

Promoters for MIR193A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001344105 304 3401 ELF3 CBX3 KLF17 ARID4B SIN3A ZNF48 RAD21 GLIS2 EGR1 ZNF143

Genomic Location for MIR193A Gene

Chromosome:
17
Start:
31,559,996 bp from pter
End:
31,560,083 bp from pter
Size:
88 bases
Orientation:
Plus strand

Genomic View for MIR193A Gene

Genes around MIR193A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR193A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR193A Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR193A Gene

Proteins for MIR193A Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR193A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR193A Gene

Domains & Families for MIR193A Gene

Gene Families for MIR193A Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR193A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR193A Gene

Function for MIR193A Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR193A Gene

Localization for MIR193A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR193A Gene

Pathways & Interactions for MIR193A Gene

SuperPathways for MIR193A Gene

PathCards logo More details on SuperPathways for MIR193A
No Data Available

Interacting Proteins for MIR193A Gene

Gene Ontology (GO) - Biological Process for MIR193A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR193A Gene

Drugs & Compounds for MIR193A Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR193A Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for MIR193A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR193A Gene

No ASD Table

Relevant External Links for MIR193A Gene

GeneLoc Exon Structure for
MIR193A
ECgene alternative splicing isoforms for
MIR193A

Expression for MIR193A Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR193A Gene

mRNA expression in normal human tissues for MIR193A Gene
mRNA expression by GTEx for MIR193A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR193A Gene:

MIR193A
genes like me logo Genes that share expression patterns with MIR193A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR193A Gene

Orthologs for MIR193A Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR193A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
 Mammalia ptr-mir-193a 35
  • 100 (a)
 OneToOne
dog
(Canis familiaris)
 Mammalia cfa-mir-193a 35
  • 96 (a)
 OneToOne
cow
(Bos Taurus)
 Mammalia bta-mir-193a 35
  • 95 (a)
 OneToOne
oppossum
(Monodelphis domestica)
 Mammalia mdo-mir-193a 35
  • 92 (a)
 OneToOne
mouse
(Mus musculus)
 Mammalia Mir193 35
  • 91 (a)
 OneToOne
lizard
(Anolis carolinensis)
 Reptilia aca-mir-193 35
  • 77 (a)
 OneToOne
zebrafish
(Danio rerio)
 Actinopterygii dre-mir-193a-1 35
  • 58 (a)
 OneToOne
Species where no ortholog for MIR193A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR193A Gene

ENSEMBL:
Gene Tree for MIR193A (if available)
TreeFam:
Gene Tree for MIR193A (if available)

Paralogs for MIR193A Gene

No data available for Paralogs for MIR193A Gene

Variants for MIR193A Gene

Sequence variations from dbSNP and Humsavar for MIR193A Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs111339896 -- 31,558,827(+) CCGGG(C/G)GGGGG upstream-variant-2KB
rs111868638 -- 31,559,101(+) GCCGG(G/T)GCCGC upstream-variant-2KB
rs112064170 -- 31,558,828(+) CGGGC(A/C/G)GGGGC upstream-variant-2KB
rs112566949 -- 31,559,361(+) GCTTC(G/T)TCGGG upstream-variant-2KB
rs112797972 -- 31,559,337(+) TCTCG(C/G)CGCCC upstream-variant-2KB

Relevant External Links for MIR193A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR193A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR193A Gene

Disorders for MIR193A Gene

Relevant External Links for MIR193A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR193A

No disorders were found for MIR193A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR193A Gene

Publications for MIR193A Gene

  1. A panel of four decreased serum microRNAs as a novel biomarker for early Parkinson's disease. (PMID: 26631297) Dong H. … Zhang C.Y. (Biomarkers 2016) 3 64
  2. MiR-193a-3p and miR-193a-5p suppress the metastasis of human osteosarcoma cells by down-regulating Rab27B and SRR, respectively. (PMID: 26913720) Pu Y. … Cai S. (Clin. Exp. Metastasis 2016) 3 64
  3. miR-193a-3p regulation of chemoradiation resistance in oesophageal cancer cells via the PSEN1 gene. (PMID: 26743123) Meng F. … Liang Y. (Gene 2016) 3 64
  4. LncRNA-UCA1 exerts oncogenic functions in non-small cell lung cancer by targeting miR-193a-3p. (PMID: 26655272) Nie W. … Li B. (Cancer Lett. 2016) 3 64
  5. MicroRNA-193a-3p and -5p suppress the metastasis of human non-small-cell lung cancer by downregulating the ERBB4/PIK3R3/mTOR/S6K2 signaling pathway. (PMID: 24469061) Yu T. … Yao M. (Oncogene 2015) 3 64

Products for MIR193A Gene

Sources for MIR193A Gene

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