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Aliases for MIR193A Gene

Subcategory (RNA class) for MIR193A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR193A Gene

  • MicroRNA 193a 2 3
  • MicroRNA 193 2
  • Hsa-Mir-193a 3
  • Hsa-Mir-193 3
  • MIRN193A 3
  • MIRN193 3

External Ids for MIR193A Gene

ORGUL Members for MIR193A Gene

Previous Symbols for MIR193A Gene

  • MIRN193
  • MIRN193A

Summaries for MIR193A Gene

Entrez Gene Summary for MIR193A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR193A Gene

MIR193A (MicroRNA 193a) is a RNA Gene, and belongs to miRNA RNA class. Diseases associated with MIR193A include endometrial adenocarcinoma.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR193A Gene

Genomics for MIR193A Gene

Genomic Location for MIR193A Gene

Start:
31,559,996 bp from pter
End:
31,560,083 bp from pter
Size:
88 bases
Orientation:
Plus strand

Genomic View for MIR193A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR193A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR193A Gene

No data available for Regulatory Elements for MIR193A Gene

Proteins for MIR193A Gene

Post-translational modifications for MIR193A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR193A Gene

Domains for MIR193A Gene

Gene Families for MIR193A Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR193A: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR193A Gene

Function for MIR193A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR193A Gene

Localization for MIR193A Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR193A Gene

Pathways for MIR193A Gene

SuperPathways for MIR193A Gene

No Data Available

Interacting Proteins for MIR193A Gene

Gene Ontology (GO) - Biological Process for MIR193A Gene

None

No data available for Pathways by source for MIR193A Gene

Transcripts for MIR193A Gene

mRNA/cDNA for MIR193A Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR193A Gene

No ASD Table

Relevant External Links for MIR193A Gene

GeneLoc Exon Structure for
MIR193A
ECgene alternative splicing isoforms for
MIR193A

Expression for MIR193A Gene

mRNA expression in normal human tissues for MIR193A Gene

genes like me logo Genes that share expressions with MIR193A: view

Orthologs for MIR193A Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR193A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-193a 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-193a 37
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-193a 37
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir193 37
  • 91 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-193a 37
  • 92 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-193 37
  • 77 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-193a-1 37
  • 58 (a)
OneToOne
Species with no ortholog for MIR193A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR193A Gene

ENSEMBL:
Gene Tree for MIR193A (if available)
TreeFam:
Gene Tree for MIR193A (if available)

Paralogs for MIR193A Gene

No data available for Paralogs for MIR193A Gene

Variants for MIR193A Gene

Sequence variations from dbSNP and Humsavar for MIR193A Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs2521776 -- 31,559,469(+) ACGTT(C/G/T)GGGCG upstream-variant-2KB
rs2521777 -- 31,559,468(+) ACGTT(C/G)GGGCG upstream-variant-2KB
rs9901835 -- 31,559,206(+) CGGTG(C/T)GGGCG upstream-variant-2KB
rs9902309 -- 31,559,447(+) AGGAG(C/T)TCGAG upstream-variant-2KB
rs56161228 -- 31,558,198(+) GGCAT(A/G)ATCTG upstream-variant-2KB

Relevant External Links for MIR193A Gene

HapMap Linkage Disequilibrium report
MIR193A

No data available for Structural Variations from Database of Genomic Variants (DGV) for MIR193A Gene

Disorders for MIR193A Gene

genes like me logo Genes that share disorders with MIR193A: view

No data available for UniProtKB/Swiss-Prot for MIR193A Gene

Publications for MIR193A Gene

  1. New microRNAs from mouse and human. (PMID: 12554859) Lagos-Quintana M. … Tuschl T. (RNA 2003) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. Patterns of known and novel small RNAs in human cervical cancer. (PMID: 17616659) Lui W.O. … Fire A. (Cancer Res. 2007) 3
  5. MicroRNA-193a represses c-kit expression and functions as a methylation-silenced tumor suppressor in acute myeloid leukemia. (PMID: 21399664) Gao X.N. … Yu L. (Oncogene 2011) 3

Products for MIR193A Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR193A
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR193A
    • Block miRNA regulation of MIR193A using miScript Target Protectors

    Sources for MIR193A Gene

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