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MIR193A Gene(RNA Gene)

MicroRNA 193a

GCID:
GC17P031559
GIFtS:
15
Genes Participants
UDN Logo

Aliases for MIR193A Gene

Subcategory (RNA class) for MIR193A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR193A Gene

  • MicroRNA 193a 2 3 5
  • MicroRNA 193 2
  • Hsa-Mir-193a 3
  • Hsa-Mir-193 3
  • Mir-193a 3
  • MIRN193A 3
  • MIRN193 3

External Ids for MIR193A Gene

ORGUL Members for MIR193A Gene

Previous HGNC Symbols for MIR193A Gene

  • MIRN193
  • MIRN193A

Previous GeneCards Identifiers for MIR193A Gene

  • GC17P026914
  • GC17P029887

Summaries for MIR193A Gene

Entrez Gene Summary for MIR193A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR193A Gene

MIR193A (MicroRNA 193a) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR193A Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR193A Gene

Genomics for MIR193A Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for MIR193A Gene

Promoters and enhancers for MIR193A Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH17I031558 Promoter/Enhancer 1.9 FANTOM5 Ensembl ENCODE dbSUPER 550.8 +0.7 680 4.7 ARID4B SIN3A DMAP1 ZNF48 YY1 GLIS2 ZNF143 ATF7 SP3 REST GC17P031561 MIR193A ENSG00000278546 RAB11FIP4 COPRS EVI2A GC17M031564 RNU6ATAC7P
GH17I031592 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 12.1 +36.3 36283 6.7 FOXA2 SIN3A ZNF48 RAD21 RCOR1 ATF7 FOS IKZF2 USF2 KAT8 RAB11FIP4 MIR193A RNU6ATAC7P RNF135 CRLF3 EVI2A ENSG00000266877 PIR51917 GC17M031638
GH17I031578 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 12.6 +20.9 20923 4.2 NFIB JUN EBF1 BATF ZIC2 RFX5 GATA3 RFXANK POLR2A ATF7 MIR193A RAB11FIP4 EVI2A EVI2B ENSG00000266877 GC17M031575
GH17I031680 Enhancer 1.2 FANTOM5 ENCODE dbSUPER 10.9 +120.2 120237 0.4 BACH1 BMI1 YBX1 BATF KLF5 RELA NFATC1 ATF7 ETV6 BCLAF1 MIR193A C17orf75 EVI2A EVI2B RHOT1 GC17M031689 PIR51917 GC17M031638
GH17I031537 Enhancer 0.9 ENCODE dbSUPER 12.3 -22.1 -22104 0.9 PKNOX1 EBF1 ZIC2 IRF4 FOXK2 POLR2A IKZF2 RUNX3 ZNF687 CBFB RAB11FIP4 MIR193A RNU6ATAC7P GC17P031541 MIR4724 GC17P031509
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR193A on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR193A Gene

Genomic Locations for MIR193A Gene
chr17:31,559,996-31,560,083
(GRCh38/hg38)
Size:
88 bases
Orientation:
Plus strand
chr17:29,887,015-29,887,102
(GRCh37/hg19)

Genomic View for MIR193A Gene

Genes around MIR193A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR193A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR193A Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR193A Gene

Proteins for MIR193A Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR193A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR193A Gene

Domains & Families for MIR193A Gene

Gene Families for MIR193A Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR193A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR193A Gene

Function for MIR193A Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Gene Ontology (GO) - Molecular Function for MIR193A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 20829195
genes like me logo Genes that share ontologies with MIR193A: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR193A Gene

Localization for MIR193A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR193A Gene

Pathways & Interactions for MIR193A Gene

SuperPathways for MIR193A Gene

PathCards logo More details on SuperPathways for MIR193A
No Data Available

Interacting Proteins for MIR193A Gene

Gene Ontology (GO) - Biological Process for MIR193A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IDA 20829195
genes like me logo Genes that share ontologies with MIR193A: view

No data available for Pathways by source and SIGNOR curated interactions for MIR193A Gene

Drugs & Compounds for MIR193A Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR193A Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for MIR193A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR193A Gene

No ASD Table

Relevant External Links for MIR193A Gene

GeneLoc Exon Structure for
MIR193A
ECgene alternative splicing isoforms for
MIR193A

Expression for MIR193A Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR193A Gene

mRNA expression in normal human tissues for MIR193A Gene
mRNA expression by GTEx for MIR193A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR193A Gene:

MIR193A
genes like me logo Genes that share expression patterns with MIR193A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR193A Gene

Orthologs for MIR193A Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR193A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
 Mammalia ptr-mir-193a 34
  • 100 (a)
 OneToOne
dog
(Canis familiaris)
 Mammalia cfa-mir-193a 34
  • 96 (a)
 OneToOne
cow
(Bos Taurus)
 Mammalia bta-mir-193a 34
  • 95 (a)
 OneToOne
oppossum
(Monodelphis domestica)
 Mammalia mdo-mir-193a 34
  • 92 (a)
 OneToOne
mouse
(Mus musculus)
 Mammalia Mir193 34
  • 91 (a)
 OneToOne
lizard
(Anolis carolinensis)
 Reptilia aca-mir-193 34
  • 77 (a)
 OneToOne
zebrafish
(Danio rerio)
 Actinopterygii dre-mir-193a-1 34
  • 58 (a)
 OneToOne
Species where no ortholog for MIR193A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR193A Gene

ENSEMBL:
Gene Tree for MIR193A (if available)
TreeFam:
Gene Tree for MIR193A (if available)

Paralogs for MIR193A Gene

No data available for Paralogs for MIR193A Gene

Variants for MIR193A Gene

Sequence variations from dbSNP and Humsavar for MIR193A Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1001234803 -- 31,559,162(+) C/G upstream_transcript_variant
rs1001271778 -- 31,559,764(+) T/C upstream_transcript_variant
rs1002085415 -- 31,559,342(+) C/T upstream_transcript_variant
rs1002244070 -- 31,559,210(+) C/CC upstream_transcript_variant
rs1002642469 -- 31,558,366(+) G/T upstream_transcript_variant

Additional Variant Information for MIR193A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR193A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR193A Gene

Disorders for MIR193A Gene

Additional Disease Information for MIR193A

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR193A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR193A Gene

Publications for MIR193A Gene

  1. MicroRNA-193a inhibits breast cancer proliferation and metastasis by downregulating WT1. (PMID: 29016617) Xie F … Hu X (PloS one 2017) 3 58
  2. Identification of plasma microRNAs as new potential biomarkers with high diagnostic power in human cutaneous melanoma. (PMID: 28466785) Fogli S … Nieri P (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017) 3 58
  3. Excess of a Rassf1-targeting microRNA, miR-193a-3p, perturbs cell division fidelity. (PMID: 28449010) Pruikkonen S … Kallio MJ (British journal of cancer 2017) 3 58
  4. Androgen receptor-regulated miRNA-193a-3p targets AJUBA to promote prostate cancer cell migration. (PMID: 28422308) Jia L … Kibel AS (The Prostate 2017) 3 58
  5. Urinary Exosomal miR-193a Can Be a Potential Biomarker for the Diagnosis of Primary Focal Segmental Glomerulosclerosis in Children. (PMID: 28246603) Huang Z … Zhang Y (BioMed research international 2017) 3 58

Products for MIR193A Gene

Sources for MIR193A Gene

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