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Aliases for MIR190B Gene

Subcategory (RNA class) for MIR190B Gene

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Quality Score for this RNA gene is

3.2

Aliases for MIR190B Gene

  • MicroRNA 190b 2 3 5
  • Hsa-Mir-190b 3
  • Mir-190b 3
  • MIRN190B 3

External Ids for MIR190B Gene

Previous HGNC Symbols for MIR190B Gene

  • MIRN190B

Previous GeneCards Identifiers for MIR190B Gene

  • GC01M152436
  • GC01M154166

Summaries for MIR190B Gene

Entrez Gene Summary for MIR190B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR190B Gene

MIR190B (MicroRNA 190b) is an RNA Gene, and is affiliated with the undefined RNA class.

fRNAdb sequence ontologies for MIR190B Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR190B Gene

Genomics for MIR190B Gene

Regulatory Elements for MIR190B Gene

Enhancers for MIR190B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F154333 1.2 Ensembl ENCODE 10.3 -140.9 -140948 2.2 PKNOX1 ARID4B SIN3A ZNF48 YY1 ZNF121 ZNF143 REST PPARG KAT8 UBE2Q1 IL6R LOC101928101 ENSG00000201129 UBAP2L MIR190B TPM3 C1orf189 UBE2Q1-AS1 ATP8B2
GH01F154479 1.2 Ensembl ENCODE 9.2 -286.3 -286258 0.8 TBL1XR1 ARNT WRNIP1 SIN3A ARID4B ZNF2 RAD21 RFX5 CHAMP1 YY1 IL6R UBE2Q1-AS1 UBE2Q1 SHE TDRD10 LOC101928101 CHRNB2 RNU7-57P ATP8B2 ENSG00000201129
GH01F154477 0.9 Ensembl ENCODE 9.2 -284.6 -284569 2.2 CTCF MTA2 MAX TRIM22 REST RAD21 ZNF664 RAD51 SMC3 ZNF24 SHE UBE2Q1-AS1 UBE2Q1 TDRD10 LOC101928101 IL6R CHRNB2 RNU7-57P ATP8B2 ENSG00000201129
GH01F153821 0.6 ENCODE 9.2 +372.2 372244 0.1 CTCF ZNF654 REST RAD21 ZNF664 SMC3 ZNF600 MLLT1 GATAD2B DENND4B CRTC2 RPS27 RAB13 RPL34P5 CREB3L4 SLC39A1 JTB UBAP2L
GH01F154478 0.4 ENCODE 9.2 -283.3 -283297 0.1 SCRT2 UBE2Q1-AS1 UBE2Q1 SHE TDRD10 LOC101928101 IL6R CHRNB2 RNU7-57P ATP8B2 ENSG00000201129
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR190B on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR190B Gene

Chromosome:
1
Start:
154,193,665 bp from pter
End:
154,193,743 bp from pter
Size:
79 bases
Orientation:
Minus strand

Genomic View for MIR190B Gene

Genes around MIR190B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR190B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR190B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR190B Gene

ORGUL Member Location for MIR190B Gene

ORGUL Member Location for MIR190B gene

Proteins for MIR190B Gene

Post-translational modifications for MIR190B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR190B Gene

Domains & Families for MIR190B Gene

Gene Families for MIR190B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR190B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR190B Gene

Function for MIR190B Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR190B Gene

Localization for MIR190B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR190B Gene

Pathways & Interactions for MIR190B Gene

SuperPathways for MIR190B Gene

No Data Available

Interacting Proteins for MIR190B Gene

Gene Ontology (GO) - Biological Process for MIR190B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR190B Gene

Transcripts for MIR190B Gene

mRNA/cDNA for MIR190B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR190B Gene

No ASD Table

Relevant External Links for MIR190B Gene

GeneLoc Exon Structure for
MIR190B
ECgene alternative splicing isoforms for
MIR190B

Expression for MIR190B Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR190B Gene:

MIR190B
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR190B Gene

Orthologs for MIR190B Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR190B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-190b 35
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-190b 35
  • 95 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-190b 35
  • 93 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-190b 35
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir190b 35
  • 90 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-190b 35
  • 42 (a)
ManyToMany
chicken
(Gallus gallus)
Aves -- 35
  • 79 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-190b 35
  • 61 (a)
ManyToMany
Species where no ortholog for MIR190B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR190B Gene

ENSEMBL:
Gene Tree for MIR190B (if available)
TreeFam:
Gene Tree for MIR190B (if available)

Paralogs for MIR190B Gene

No data available for Paralogs for MIR190B Gene

Variants for MIR190B Gene

Sequence variations from dbSNP and Humsavar for MIR190B Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs112266955 -- 154,194,555(+) CTCTC(C/T)TCTTC upstream-variant-2KB
rs113471443 -- 154,193,167(+) CTGAG(A/G)GTTAA downstream-variant-500B, upstream-variant-2KB
rs114475185 -- 154,194,355(+) CCTCC(A/G)GGCAT upstream-variant-2KB
rs138477804 -- 154,193,389(+) AAAAT(-/G)GGGGG downstream-variant-500B, upstream-variant-2KB
rs138510334 -- 154,194,483(+) GAAAC(G/T)AAGGC upstream-variant-2KB

Relevant External Links for MIR190B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR190B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR190B Gene

Disorders for MIR190B Gene

Relevant External Links for MIR190B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR190B

No disorders were found for MIR190B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR190B Gene

Publications for MIR190B Gene

  1. MiR-190b, the highest up-regulated miRNA in ERI+-positive compared to ERI+-negative breast tumors, a new biomarker in breast cancers? (PMID: 26141719) Cizeron-Clairac G. … Callens C. (BMC Cancer 2015) 3 64
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
  5. Identification and classification of conserved RNA secondary structures in the human genome. (PMID: 16628248) Pedersen J.S. … Haussler D. (PLoS Comput. Biol. 2006) 1

Products for MIR190B Gene

Sources for MIR190B Gene

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