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Aliases for MIR1908 Gene

Subcategory (RNA class) for MIR1908 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1908 Gene

  • MicroRNA 1908 2 3 5
  • Hsa-Mir-1908 3
  • Mir-1908 3
  • MIRN1908 3

External Ids for MIR1908 Gene

Previous HGNC Symbols for MIR1908 Gene

  • MIRN1908

Previous GeneCards Identifiers for MIR1908 Gene

  • GC00U923135
  • GC11M061340
  • GC11M061582

Summaries for MIR1908 Gene

Entrez Gene Summary for MIR1908 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1908 Gene

MIR1908 (MicroRNA 1908) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are alpha-linolenic (omega3) and linoleic (omega6) acid metabolism and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha).

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1908 Gene

Genomics for MIR1908 Gene

Regulatory Elements for MIR1908 Gene

Enhancers for MIR1908 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G061791 1.4 ENCODE dbSUPER 12.2 +22.5 22515 3.1 HDGF PKNOX1 CREB3L1 ARNT AGO1 WRNIP1 ARID4B SIN3A DMAP1 ZBTB7B FADS2 MIR1908 FADS1 EEF1G BEST1 EML3 TMEM258 FEN1
GH11G061813 1.4 ENCODE dbSUPER 0.7 -1.0 -969 4.5 CREB3L1 AGO1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC TBX21 MEF2D FADS2 ROM1 BEST1 ENSG00000267811 EML3 MIR1908 PIR43939
GH11G061812 0.9 ENCODE dbSUPER 0.7 +2.3 2337 0.1 MXI1 RNF2 SIN3A ZNF592 ZNF335 HIC1 GLIS2 POLR2A KDM5B HNRNPL BEST1 MIR1908 FADS2
GH11G061796 1.4 Ensembl ENCODE dbSUPER 0.4 +17.4 17419 2.0 TBL1XR1 AGO1 ZBTB40 ZNF2 RAD21 RFX5 YY1 SCRT2 ZNF143 MIXL1 FADS2 FADS1 DKFZP434K028 BEST1 MIR1908
GH11G061799 1.2 dbSUPER 0.4 +15.1 15124 1.9 HDGF FOXA2 CREB3L1 MLX ARNT AGO1 ZFP64 ARID4B SIN3A DMAP1 FADS2 B3GAT3 MIR1908
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1908 on UCSC Golden Path with GeneCards custom track

Promoters for MIR1908 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000040341 -960 2801 HDGF HNRNPUL1 PKNOX1 CREB3L1 ARNT AGO1 ARID4B SIN3A DMAP1 YY1

Genomic Location for MIR1908 Gene

Chromosome:
11
Start:
61,815,161 bp from pter
End:
61,815,240 bp from pter
Size:
80 bases
Orientation:
Minus strand

Genomic View for MIR1908 Gene

Genes around MIR1908 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1908 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1908 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1908 Gene

ORGUL Member Location for MIR1908 Gene

ORGUL Member Location for MIR1908 gene

Proteins for MIR1908 Gene

Post-translational modifications for MIR1908 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1908 Gene

Domains & Families for MIR1908 Gene

Gene Families for MIR1908 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1908: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1908 Gene

Function for MIR1908 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1908 Gene

Localization for MIR1908 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1908 Gene

Drugs & Compounds for MIR1908 Gene

No Compound Related Data Available

Transcripts for MIR1908 Gene

mRNA/cDNA for MIR1908 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1908 Gene

No ASD Table

Relevant External Links for MIR1908 Gene

GeneLoc Exon Structure for
MIR1908
ECgene alternative splicing isoforms for
MIR1908

Expression for MIR1908 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1908 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1908 Gene:

MIR1908
genes like me logo Genes that share expression patterns with MIR1908: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1908 Gene

Orthologs for MIR1908 Gene

Evolution for MIR1908 Gene

ENSEMBL:
Gene Tree for MIR1908 (if available)
TreeFam:
Gene Tree for MIR1908 (if available)

No data available for Orthologs for MIR1908 Gene

Paralogs for MIR1908 Gene

No data available for Paralogs for MIR1908 Gene

Variants for MIR1908 Gene

Sequence variations from dbSNP and Humsavar for MIR1908 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1001969539 -- 61,816,128(+) GCGCT(C/G)CCTCT intron-variant, upstream-variant-2KB
rs1003732447 -- 61,814,808(+) TACAG(A/G)AAAGT intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1004964674 -- 61,815,221(+) CGCCG(C/T)CCCCG intron-variant, nc-transcript-variant, upstream-variant-2KB, reference, synonymous-codon
rs1006483193 -- 61,816,469(+) TCGGT(A/G)TTTGG intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs1008508591 -- 61,815,885(+) TCTGG(G/T)GGTCC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1908 Gene

Variant ID Type Subtype PubMed ID
nsv528697 CNV loss 19592680

Relevant External Links for MIR1908 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1908

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1908 Gene

Disorders for MIR1908 Gene

Relevant External Links for MIR1908

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1908

No disorders were found for MIR1908 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1908 Gene

Publications for MIR1908 Gene

  1. miR-1908 Overexpression Inhibits Proliferation, Changing Akt Activity and p53 Expression in Hypoxic NSCLC Cells. (PMID: 27178817) Ma Y. … Kong R. (Oncol. Res. 2016) 3 64
  2. MicroRNA-1908 is a biomarker for poor prognosis in human osteosarcoma. (PMID: 27097944) Lian D. … Liu N.S. (Eur Rev Med Pharmacol Sci 2016) 3 64
  3. [Transfected miR-1908 inhibits renal fibrosis via targeting transforming growth factor beta 1]. (PMID: 26648305) Xie F. … Shan Z. (Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2015) 3 64
  4. MicroRNA-1908 is upregulated in human osteosarcoma and regulates cell proliferation and migration by repressing PTEN expression. (PMID: 26328886) Yuan H. … Gao Y. (Oncol. Rep. 2015) 3 64
  5. MicroRNA-1908 functions as a glioblastoma oncogene by suppressing PTEN tumor suppressor pathway. (PMID: 26265437) Xia X. … He S. (Mol. Cancer 2015) 3 64

Products for MIR1908 Gene

Sources for MIR1908 Gene

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