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Aliases for MIR18B Gene

Subcategory (RNA class) for MIR18B Gene


Quality Score for this RNA gene is


Aliases for MIR18B Gene

  • MicroRNA 18b 2 3
  • Hsa-Mir-18b 3
  • MIRN18B 3

External Ids for MIR18B Gene

Previous HGNC Symbols for MIR18B Gene

  • MIRN18B

Previous GeneCards Identifiers for MIR18B Gene

  • GC0XM133149
  • GC0XM133156
  • GC0XM133304

Summaries for MIR18B Gene

Entrez Gene Summary for MIR18B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR18B Gene

MIR18B (MicroRNA 18b) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR18B Gene

Genomics for MIR18B Gene

Genomic Location for MIR18B Gene

134,170,017 bp from pter
134,170,125 bp from pter
109 bases
Minus strand

Genomic View for MIR18B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR18B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR18B Gene

No data available for Regulatory Elements for MIR18B Gene

Proteins for MIR18B Gene

Post-translational modifications for MIR18B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR18B Gene

Domains for MIR18B Gene

Gene Families for MIR18B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR18B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR18B Gene

Function for MIR18B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR18B Gene

Localization for MIR18B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR18B Gene

Pathways for MIR18B Gene

SuperPathways for MIR18B Gene

No Data Available

Interacting Proteins for MIR18B Gene

Gene Ontology (GO) - Biological Process for MIR18B Gene


No data available for Pathways by source for MIR18B Gene

Transcripts for MIR18B Gene

mRNA/cDNA for MIR18B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR18B Gene

No ASD Table

Relevant External Links for MIR18B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR18B Gene

mRNA expression in normal human tissues for MIR18B Gene

genes like me logo Genes that share expressions with MIR18B: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR18B Gene

Orthologs for MIR18B Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR18B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-18b 36
  • 95 (a)
(Canis familiaris)
Mammalia cfa-mir-18b 36
  • 95 (a)
(Monodelphis domestica)
Mammalia mdo-mir-18b 36
  • 65 (a)
(Mus musculus)
Mammalia Mir18b 36
  • 95 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-18 36
  • 57 (a)
(Pan troglodytes)
Mammalia ptr-mir-18a 36
  • 70 (a)
(Gallus gallus)
Aves gga-mir-18b 36
  • 81 (a)
(Anolis carolinensis)
Reptilia aca-mir-18b 36
  • 82 (a)
(Danio rerio)
Actinopterygii dre-mir-18c 36
  • 68 (a)
Species with no ortholog for MIR18B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR18B Gene

Gene Tree for MIR18B (if available)
Gene Tree for MIR18B (if available)

Paralogs for MIR18B Gene

No data available for Paralogs for MIR18B Gene

Variants for MIR18B Gene

Relevant External Links for MIR18B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR18B Gene

Disorders for MIR18B Gene

No disorders were found for MIR18B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR18B Gene

Publications for MIR18B Gene

  1. c-Myc-regulated microRNAs modulate E2F1 expression. (PMID: 15944709) O'Donnell K.A. … Mendell J.T. (Nature 2005) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines. (PMID: 19684618) Leivonen S.K. … Kallioniemi O. (Oncogene 2009) 3
  5. Altered methylation at microRNA-associated CpG islands in hereditary and sporadic carcinomas: a methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA)-based approach. (PMID: 21327300) Pavicic W. … PeltomAoki P. (Mol. Med. 2011) 3

Products for MIR18B Gene

Sources for MIR18B Gene

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