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Aliases for MIR18A Gene

Subcategory (RNA class) for MIR18A Gene


Quality Score for this RNA gene is


Aliases for MIR18A Gene

  • MicroRNA 18a 2 3
  • MIRN18A 3 6
  • MicroRNA 18 2
  • Hsa-Mir-18a 3
  • Hsa-Mir-18 3
  • MiRNA18A 3
  • MiR-18 3
  • MIRN18 3
  • MIR18 3

External Ids for MIR18A Gene

Previous HGNC Symbols for MIR18A Gene

  • MIRN18
  • MIRN18A

Previous GeneCards Identifiers for MIR18A Gene

  • GC13P090866
  • GC13P090876
  • GC13P092015
  • GC13P092023
  • GC13P092030
  • GC13P092038
  • GC13P092047
  • GC13P092057
  • GC13P092066
  • GC13P092076
  • GC13P092084
  • GC13P092098
  • GC13P092112

Summaries for MIR18A Gene

Entrez Gene Summary for MIR18A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. This gene is a member of an oncogenic miRNA cluster that is overexpressed in multiple cancers. The miRNA encoded by this gene functions as a tumor suppressor by targeting Dicer expression. [provided by RefSeq, May 2012]

GeneCards Summary for MIR18A Gene

MIR18A (MicroRNA 18a) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer and miRNAs involved in DDR.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR18A Gene

Genomics for MIR18A Gene

Genomic Location for MIR18A Gene

91,350,743 bp from pter
91,350,834 bp from pter
92 bases
Plus strand

Genomic View for MIR18A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR18A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR18A Gene

No data available for Regulatory Elements for MIR18A Gene

Proteins for MIR18A Gene

Post-translational modifications for MIR18A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR18A Gene

Domains for MIR18A Gene

Gene Families for MIR18A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR18A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR18A Gene

Function for MIR18A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR18A Gene

Localization for MIR18A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR18A Gene

Pathways for MIR18A Gene

genes like me logo Genes that share pathways with MIR18A: view

Pathways by source for MIR18A Gene

1 BioSystems pathway for MIR18A Gene
1 KEGG pathway for MIR18A Gene

Interacting Proteins for MIR18A Gene

Gene Ontology (GO) - Biological Process for MIR18A Gene


Transcripts for MIR18A Gene

mRNA/cDNA for MIR18A Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR18A Gene

No ASD Table

Relevant External Links for MIR18A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR18A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

genes like me logo Genes that share expressions with MIR18A: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR18A Gene

Orthologs for MIR18A Gene

Evolution for MIR18A Gene

Gene Tree for MIR18A (if available)
Gene Tree for MIR18A (if available)

No data available for Orthologs for MIR18A Gene

Paralogs for MIR18A Gene

No data available for Paralogs for MIR18A Gene

Variants for MIR18A Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR18A Gene

Variant ID Type Subtype PubMed ID
nsv832679 CNV Gain 17160897

Relevant External Links for MIR18A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR18A Gene

Disorders for MIR18A Gene

No disorders were found for MIR18A Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR18A Gene

Publications for MIR18A Gene

  1. Identification of novel genes coding for small expressed RNAs. (PMID: 11679670) Lagos-Quintana M. … Tuschl T. (Science 2001) 3
  2. miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. (PMID: 11914277) Mourelatos Z. … Dreyfuss G. (Genes Dev. 2002) 3
  3. Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma. (PMID: 15126345) Ota A. … Seto M. (Cancer Res. 2004) 3
  4. Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells. (PMID: 15325244) Kasashima K. … Kozu T. (Biochem. Biophys. Res. Commun. 2004) 3
  5. Identification of human fetal liver miRNAs by a novel method. (PMID: 15978578) Fu H. … Zheng X. (FEBS Lett. 2005) 3

Products for MIR18A Gene

Sources for MIR18A Gene

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