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Aliases for MIR18A Gene

Subcategory (RNA class) for MIR18A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR18A Gene

  • MicroRNA 18a 2 3 5
  • MicroRNA 18 2
  • Hsa-Mir-18a 3
  • Hsa-Mir-18 3
  • MiRNA18A 3
  • Mir-18a 3
  • MIRN18A 3
  • MiR-18 3
  • MIRN18 3
  • MIR18 3

External Ids for MIR18A Gene

Previous HGNC Symbols for MIR18A Gene

  • MIRN18
  • MIRN18A

Previous GeneCards Identifiers for MIR18A Gene

  • GC13P090866
  • GC13P090876
  • GC13P092015
  • GC13P092023
  • GC13P092030
  • GC13P092038
  • GC13P092047
  • GC13P092057
  • GC13P092066
  • GC13P092076
  • GC13P092084
  • GC13P092098
  • GC13P092112
  • GC13P091351
  • GC13P091356

Summaries for MIR18A Gene

Entrez Gene Summary for MIR18A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR18A Gene

MIR18A (MicroRNA 18a) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are miRNAs involved in DDR and MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR18A Gene

Genomics for MIR18A Gene

Genomic Location for MIR18A Gene

Chromosome:
13
Start:
91,350,743 bp from pter
End:
91,350,834 bp from pter
Size:
92 bases
Orientation:
Plus strand

Genomic View for MIR18A Gene

Genes around MIR18A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR18A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR18A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR18A Gene

No data available for Regulatory Elements for MIR18A Gene

Proteins for MIR18A Gene

Post-translational modifications for MIR18A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR18A Gene

Domains & Families for MIR18A Gene

Gene Families for MIR18A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR18A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR18A Gene

Function for MIR18A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR18A Gene

Localization for MIR18A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR18A Gene

Pathways & Interactions for MIR18A Gene

genes like me logo Genes that share pathways with MIR18A: view

Pathways by source for MIR18A Gene

1 BioSystems pathway for MIR18A Gene
1 KEGG pathway for MIR18A Gene

Interacting Proteins for MIR18A Gene

Gene Ontology (GO) - Biological Process for MIR18A Gene

None

No data available for SIGNOR curated interactions for MIR18A Gene

Drugs & Compounds for MIR18A Gene

No Compound Related Data Available

Transcripts for MIR18A Gene

mRNA/cDNA for MIR18A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR18A Gene

No ASD Table

Relevant External Links for MIR18A Gene

GeneLoc Exon Structure for
MIR18A
ECgene alternative splicing isoforms for
MIR18A

Expression for MIR18A Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR18A Gene

Orthologs for MIR18A Gene

Evolution for MIR18A Gene

ENSEMBL:
Gene Tree for MIR18A (if available)
TreeFam:
Gene Tree for MIR18A (if available)

No data available for Orthologs for MIR18A Gene

Paralogs for MIR18A Gene

No data available for Paralogs for MIR18A Gene

Variants for MIR18A Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR18A Gene

Variant ID Type Subtype PubMed ID
nsv832679 CNV Gain 17160897

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Variation tolerance and Relevant External Links for MIR18A Gene

Disorders for MIR18A Gene

Relevant External Links for MIR18A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR18A

No disorders were found for MIR18A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR18A Gene

Publications for MIR18A Gene

  1. Effect of miR-18a overexpression on the radiosensitivity of non-small cell lung cancer. (PMID: 25755757) Shen Z. … Zhu X. (Int J Clin Exp Pathol 2015) 3 67
  2. Circulating miR-18a in plasma contributes to cancer detection and monitoring in patients with gastric cancer. (PMID: 24626859) Tsujiura M. … Otsuji E. (Gastric Cancer 2015) 3
  3. Elevated p53 promotes the processing of miR-18a to decrease estrogen receptor-I+ in female hepatocellular carcinoma. (PMID: 24975878) Li C.L. … Yeh S.H. (Int. J. Cancer 2015) 3
  4. MiR-18a increased the permeability of BTB via RUNX1 mediated down-regulation of ZO-1, occludin and claudin-5. (PMID: 25452107) Miao Y.S. … Xue Y.X. (Cell. Signal. 2015) 3
  5. Suppression of microRNA-18a expression inhibits invasion and promotes apoptosis of human trophoblast cells by targeting the estrogen receptor I+ gene. (PMID: 25955393) Zhu X. … Yao Y. (Mol Med Rep 2015) 3

Products for MIR18A Gene

Sources for MIR18A Gene

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