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Aliases for MIR184 Gene

Subcategory (RNA class) for MIR184 Gene


Quality Score for this RNA gene is


Aliases for MIR184 Gene

  • MicroRNA 184 2 3 5
  • Hsa-Mir-184 3
  • MiR-184 3
  • MIRN184 3
  • EDICT 3

External Ids for MIR184 Gene

ORGUL Members for MIR184 Gene

Previous HGNC Symbols for MIR184 Gene

  • MIRN184

Previous GeneCards Identifiers for MIR184 Gene

  • GC15P077293
  • GC15P079502

Summaries for MIR184 Gene

Entrez Gene Summary for MIR184 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR184 Gene

MIR184 (MicroRNA 184) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR184 include Edict Syndrome and Mir184. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins..

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR184 Gene

Genomics for MIR184 Gene

Regulatory Elements for MIR184 Gene

Enhancers for MIR184 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15F079002 1.2 Ensembl ENCODE 9.3 -205.7 -205688 4.2 ELF3 TBL1XR1 ZFP64 BMI1 RAD21 EGR1 ETV6 FOS CREM EGR2 ENSG00000177699 CTSH MIR184 RASGRF1 LOC105370917 GC15P079059
GH15F079184 0.7 ENCODE 11.1 -25.2 -25225 0.2 CTCF ZNF654 WRNIP1 CEBPB TRIM22 REST ZNF2 RAD21 ZNF324 KLF16 MIR184 ENSG00000177699 CTSH GC15P079181 GC15P079204
GH15F079185 0.6 ENCODE 11.1 -24.5 -24455 0.1 CTCF ZNF366 ZNF512 ETV6 ZBTB40 MIR184 ENSG00000177699 CTSH GC15P079181 GC15P079204
GH15F079035 0.6 ENCODE 10.7 -174.4 -174355 0.2 CTCF IKZF1 JUNB EBF1 CREM RASGRF1 MIR184 ENSG00000177699 GC15P079059 LOC105370917
GH15F079039 0.3 FANTOM5 10.7 -170.2 -170209 0.2 RASGRF1 MIR184 ENSG00000177699 GC15P079059 LOC105370917
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR184 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR184 Gene

79,209,788 bp from pter
79,209,871 bp from pter
84 bases
Plus strand

Genomic View for MIR184 Gene

Genes around MIR184 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR184 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR184 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR184 Gene

Proteins for MIR184 Gene

Post-translational modifications for MIR184 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR184 Gene

Domains & Families for MIR184 Gene

Gene Families for MIR184 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR184: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR184 Gene

Function for MIR184 Gene

Human Phenotype Ontology for MIR184 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR184 Gene

Localization for MIR184 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR184 Gene

Pathways & Interactions for MIR184 Gene

genes like me logo Genes that share pathways with MIR184: view

Pathways by source for MIR184 Gene

1 BioSystems pathway for MIR184 Gene

Interacting Proteins for MIR184 Gene

Gene Ontology (GO) - Biological Process for MIR184 Gene


No data available for SIGNOR curated interactions for MIR184 Gene

Transcripts for MIR184 Gene

mRNA/cDNA for MIR184 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR184 Gene

No ASD Table

Relevant External Links for MIR184 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR184 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR184 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR184 Gene:

genes like me logo Genes that share expression patterns with MIR184: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR184 Gene

Orthologs for MIR184 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR184 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-184 35
  • 100 (a)
(Canis familiaris)
Mammalia cfa-mir-184 35
  • 99 (a)
(Bos Taurus)
Mammalia bta-mir-184 35
  • 96 (a)
(Mus musculus)
Mammalia Mir184 35
  • 94 (a)
(Monodelphis domestica)
Mammalia mdo-mir-184 35
  • 92 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-184 35 35
  • 52 (a)
(Gallus gallus)
Aves gga-mir-184 35
  • 82 (a)
(Danio rerio)
Actinopterygii dre-mir-184-2 35
  • 75 (a)
dre-mir-184-1 35
  • 74 (a)
Species where no ortholog for MIR184 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR184 Gene

Gene Tree for MIR184 (if available)
Gene Tree for MIR184 (if available)

Paralogs for MIR184 Gene

No data available for Paralogs for MIR184 Gene

Variants for MIR184 Gene

Sequence variations from dbSNP and Humsavar for MIR184 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs111386548 -- 79,207,845(+) TGGGA(A/C)CTTGG intron-variant, upstream-variant-2KB
rs112085210 -- 79,208,070(+) TGACC(A/C/G)CTCCA intron-variant, upstream-variant-2KB
rs112994281 -- 79,210,329(+) TTTCG(A/G)TTTAT intron-variant, downstream-variant-500B
rs113530794 -- 79,209,655(+) CAAAG(C/T)AGAAG intron-variant, upstream-variant-2KB
rs114913279 -- 79,207,798(+) TTATA(A/T)ACGTG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR184 Gene

Variant ID Type Subtype PubMed ID
esv2760042 CNV gain 17122850

Relevant External Links for MIR184 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR184 Gene

Disorders for MIR184 Gene

MalaCards: The human disease database

(3) MalaCards diseases for MIR184 Gene - From: OMIM, ClinVar, Orphanet, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
edict syndrome
  • endothelial dystrophy, iris hypoplasia, congenital cataract and stromal thinning syndrome
sebaceous adenocarcinoma
  • adenocarcinoma of the sebaceous gland
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR184

Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR184: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR184 Gene

Publications for MIR184 Gene

  1. microRNA 184 regulates expression of NFAT1 in umbilical cord blood CD4+ T cells. (PMID: 19286996) Weitzel R.P. … Laughlin M.J. (Blood 2009) 3 22 64
  2. Inverse relationship between microRNA-155 and -184 expression with increasing conjunctival inflammation during ocular Chlamydia trachomatis infection. (PMID: 26842862) Derrick T. … Holland M.J. (BMC Infect. Dis. 2016) 3 64
  3. Mutational Analysis of Pre-miR-184 and hsa-mir-568 in Greek Patients With Sporadic Keratoconus. (PMID: 26845316) Moschos M.M. … Gazouli M. (Cornea 2016) 3 64
  4. Down-Regulation of MicroRNA-184 Is Associated With Corneal Neovascularization. (PMID: 27018842) Zong R. … Zhou Y. (Invest. Ophthalmol. Vis. Sci. 2016) 3 64
  5. Independent origin of c.57 Ca88>a88T mutation in MIR184 associated with inherited corneal and lens abnormalities. (PMID: 25373792) Bykhovskaya Y. … Rabinowitz Y.S. (Ophthalmic Genet. 2015) 3 64

Products for MIR184 Gene

Sources for MIR184 Gene

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