Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR181A1 Gene

Subcategory (RNA class) for MIR181A1 Gene

miRNA

Quality Score for this RNA gene is

9.2

Aliases for MIR181A1 Gene

  • MicroRNA 181a-1 2 3
  • MicroRNA 213 2 3
  • MIRN181A1 3 6
  • MIR213 3 6
  • Hsa-Mir-181a-1 3
  • Hsa-Mir-213 3
  • Mir-213 3
  • MIRN213 3

External Ids for MIR181A1 Gene

Previous HGNC Symbols for MIR181A1 Gene

  • MIRN213
  • MIRN181A1

Previous GeneCards Identifiers for MIR181A1 Gene

  • GC01M197097
  • GC01M198829
  • GC01M198830
  • GC01M198831
  • GC01M198836

Summaries for MIR181A1 Gene

Entrez Gene Summary for MIR181A1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR181A1 Gene

MIR181A1 (MicroRNA 181a-1) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR181A1 include oral squamous cell carcinoma. Among its related pathways are MicroRNAs in cancer and miRNAs involved in DDR.

fRNAdb sequence ontologies for MIR181A1 Gene - the ORGUL cluster for this gene includes several descriptions:

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR181A1

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR181A1 Gene

Genomics for MIR181A1 Gene

Genomic Location for MIR181A1 Gene

Start:
198,859,044 bp from pter
End:
198,859,153 bp from pter
Size:
110 bases
Orientation:
Minus strand

Genomic View for MIR181A1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR181A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR181A1 Gene

ORGUL Member Location for MIR181A1 Gene

ORGUL Member Location for MIR181A1 gene

No data available for Regulatory Elements for MIR181A1 Gene

Proteins for MIR181A1 Gene

Post-translational modifications for MIR181A1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR181A1 Gene

Domains for MIR181A1 Gene

Gene Families for MIR181A1 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR181A1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR181A1 Gene

Function for MIR181A1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR181A1 Gene

Localization for MIR181A1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR181A1 Gene

Pathways for MIR181A1 Gene

genes like me logo Genes that share pathways with MIR181A1: view

Pathways by source for MIR181A1 Gene

1 BioSystems pathway for MIR181A1 Gene
1 KEGG pathway for MIR181A1 Gene

Interacting Proteins for MIR181A1 Gene

Gene Ontology (GO) - Biological Process for MIR181A1 Gene

None

Transcripts for MIR181A1 Gene

fRNAdb Secondary structures for MIR181A1 Gene

  • hsa-miR-181a-5p_MIMAT0000256_Homo_sapiens_miR-181a-5p_mature
  • FR284577

mRNA/cDNA for MIR181A1 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR181A1 Gene

No ASD Table

Relevant External Links for MIR181A1 Gene

GeneLoc Exon Structure for
MIR181A1
ECgene alternative splicing isoforms for
MIR181A1

Expression for MIR181A1 Gene

mRNA expression in normal human tissues for MIR181A1 Gene

genes like me logo Genes that share expressions with MIR181A1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR181A1 Gene

Orthologs for MIR181A1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR181A1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-181a-1 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-181a-1 36
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-181a-1 36
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir181a-1 36
  • 97 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-181a-1 36
  • 98 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-181a-1 36
  • 68 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-181a-1 36
  • 87 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-181a-1 36
  • 73 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii CU571393.1 36
  • 81 (a)
OneToMany
dre-mir-181a-1 36
  • 82 (a)
OneToMany
Species with no ortholog for MIR181A1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR181A1 Gene

ENSEMBL:
Gene Tree for MIR181A1 (if available)
TreeFam:
Gene Tree for MIR181A1 (if available)

Paralogs for MIR181A1 Gene

No data available for Paralogs for MIR181A1 Gene

Variants for MIR181A1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR181A1 Gene

Variant ID Type Subtype PubMed ID
nsv873081 CNV Loss 21882294
nsv873082 CNV Loss 21882294

Relevant External Links for MIR181A1 Gene

HapMap Linkage Disequilibrium report
MIR181A1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR181A1 Gene

Disorders for MIR181A1 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for MIR181A1 Gene including...

Search for MIR181A1 Gene in MalaCards »
genes like me logo Genes that share disorders with MIR181A1: view

No data available for UniProtKB/Swiss-Prot for MIR181A1 Gene

Publications for MIR181A1 Gene

  1. Numerous microRNPs in neuronal cells containing novel microRNAs. (PMID: 12554860) Dostie J. … Dreyfuss G. (RNA 2003) 3
  2. Vertebrate microRNA genes. (PMID: 12624257) Lim L.P. … Bartel D.P. (Science 2003) 3
  3. New human and mouse microRNA genes found by homology search. (PMID: 15634332) Weber M.J. (FEBS J. 2005) 3
  4. Extensive modulation of a set of microRNAs in primary glioblastoma. (PMID: 16039986) CiafrA" S.A. … Farace M.G. (Biochem. Biophys. Res. Commun. 2005) 3
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR181A1 Gene

Sources for MIR181A1 Gene

Back to Top

Content