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Aliases for MIR17 Gene

Subcategory (RNA class) for MIR17 Gene


Quality Score for this RNA gene is


Aliases for MIR17 Gene

  • MicroRNA 17 2 3
  • MIRN17 3 6
  • MIR91 3 6
  • Hsa-Mir-17 3
  • MIR17-5p 3
  • MiR17-3p 3
  • MiRNA17 3
  • MiRNA91 3
  • MIRN91 3
  • MiR-17 3

External Ids for MIR17 Gene

Previous HGNC Symbols for MIR17 Gene

  • MIRN17

Previous GeneCards Identifiers for MIR17 Gene

  • GC13P090870
  • GC13P090878
  • GC13P092002

Summaries for MIR17 Gene

Entrez Gene Summary for MIR17 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. The precursor microRNA encoded by this gene produces two mature miRNAs from its 5-prime and 3-prime ends, respectively. [provided by RefSeq, May 2012]

GeneCards Summary for MIR17 Gene

MIR17 (MicroRNA 17) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR17 include colorectal adenoma and oral squamous cell carcinoma. Among its related pathways are MicroRNAs in cancer and miRNAs involved in DDR.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR17 Gene

Genomics for MIR17 Gene

Genomic Location for MIR17 Gene

91,350,605 bp from pter
91,350,688 bp from pter
84 bases
Plus strand

Genomic View for MIR17 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR17 Gene

No data available for Regulatory Elements for MIR17 Gene

Proteins for MIR17 Gene

Post-translational modifications for MIR17 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR17 Gene

Domains for MIR17 Gene

Gene Families for MIR17 Gene

  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR17: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR17 Gene

Function for MIR17 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR17 Gene

Localization for MIR17 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR17 Gene

Pathways for MIR17 Gene

genes like me logo Genes that share pathways with MIR17: view

Pathways by source for MIR17 Gene

1 BioSystems pathway for MIR17 Gene
1 KEGG pathway for MIR17 Gene

Interacting Proteins for MIR17 Gene

Gene Ontology (GO) - Biological Process for MIR17 Gene


Transcripts for MIR17 Gene

mRNA/cDNA for MIR17 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR17 Gene

No ASD Table

Relevant External Links for MIR17 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR17 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR17 Gene

Orthologs for MIR17 Gene

Evolution for MIR17 Gene

Gene Tree for MIR17 (if available)
Gene Tree for MIR17 (if available)

No data available for Orthologs for MIR17 Gene

Paralogs for MIR17 Gene

No data available for Paralogs for MIR17 Gene

Variants for MIR17 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR17 Gene

Variant ID Type Subtype PubMed ID
nsv832679 CNV Gain 17160897

Relevant External Links for MIR17 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR17 Gene

Disorders for MIR17 Gene

Relevant External Links for MIR17

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with MIR17: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for MIR17 Gene

Publications for MIR17 Gene

  1. Association between hsa-mir-146a genotype and tumor age-of-onset in BRCA1/BRCA2-negative familial breast and ovarian cancer patients. (PMID: 20810544) Pastrello C. … Maestro R. (Carcinogenesis 2010) 3 48
  2. Novel genetic variants in microRNA genes and familial breast cancer. (PMID: 19048628) Shen J. … Zhao H. (Int. J. Cancer 2009) 3 48
  3. MicroRNA regulation of a cancer network: consequences of the feedback loops involving miR-17-92, E2F, and Myc. (PMID: 19066217) Aguda B.D. … Marsh C.B. (Proc. Natl. Acad. Sci. U.S.A. 2008) 3
  4. miR-34a, miR-29c and miR-17-5p are downregulated in CLL patients with TP53 abnormalities. (PMID: 19158830) Mraz M. … Pospisilova S. (Leukemia 2009) 3
  5. Specific expression of miR-17-5p and miR-127 in testicular and central nervous system diffuse large B-cell lymphoma. (PMID: 19287466) Robertus J.L. … van den Berg A. (Mod. Pathol. 2009) 3

Products for MIR17 Gene

Sources for MIR17 Gene

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