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Aliases for MIR15B Gene

Subcategory (RNA class) for MIR15B Gene

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Quality Score for this RNA gene is

3

Aliases for MIR15B Gene

  • MicroRNA 15b 2 3
  • Hsa-Mir-15b 3
  • MiR-15b 3
  • MIRN15B 3

External Ids for MIR15B Gene

ORGUL Members for MIR15B Gene

Previous Symbols for MIR15B Gene

  • MIRN15B

Summaries for MIR15B Gene

Entrez Gene Summary for MIR15B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR15B Gene

MIR15B (MicroRNA 15b) is an RNA Gene, and belongs to the undefined RNA class. Among its related pathways are MicroRNAs in cancer and MicroRNAs in cardiomyocyte hypertrophy.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR15B Gene

Genomics for MIR15B Gene

Genomic Location for MIR15B Gene

Start:
160,404,588 bp from pter
End:
160,404,685 bp from pter
Size:
98 bases
Orientation:
Plus strand

Genomic View for MIR15B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR15B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR15B Gene

No data available for Regulatory Elements for MIR15B Gene

Proteins for MIR15B Gene

Post-translational modifications for MIR15B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR15B Gene

Domains for MIR15B Gene

Gene Families for MIR15B Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR15B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR15B Gene

Function for MIR15B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR15B Gene

Localization for MIR15B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR15B Gene

Pathways for MIR15B Gene

genes like me logo Genes that share pathways with MIR15B: view

Pathways by source for MIR15B Gene

2 BioSystems pathways for MIR15B Gene
1 KEGG pathway for MIR15B Gene

Interacting Proteins for MIR15B Gene

Gene Ontology (GO) - Biological Process for MIR15B Gene

None

Transcripts for MIR15B Gene

mRNA/cDNA for MIR15B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR15B Gene

No ASD Table

Relevant External Links for MIR15B Gene

GeneLoc Exon Structure for
MIR15B
ECgene alternative splicing isoforms for
MIR15B

Expression for MIR15B Gene

mRNA expression in normal human tissues for MIR15B Gene

genes like me logo Genes that share expressions with MIR15B: view

No data available for mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR15B Gene

Orthologs for MIR15B Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR15B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-15b 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-15b 36
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-15b 36
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir15b 36
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-15a 36
  • 65 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-15b 36
  • 64 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-15b 36
  • 93 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-15a 36
  • 82 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-15c 36
  • 72 (a)
OneToOne
Species with no ortholog for MIR15B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR15B Gene

ENSEMBL:
Gene Tree for MIR15B (if available)
TreeFam:
Gene Tree for MIR15B (if available)

Paralogs for MIR15B Gene

No data available for Paralogs for MIR15B Gene

Variants for MIR15B Gene

Relevant External Links for MIR15B Gene

HapMap Linkage Disequilibrium report
MIR15B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR15B Gene

Disorders for MIR15B Gene

No disorders were found for MIR15B Gene.

No data available for UniProtKB/Swiss-Prot for MIR15B Gene

Publications for MIR15B Gene

  1. Identification of tissue-specific microRNAs from mouse. (PMID: 12007417) Lagos-Quintana M. … Tuschl T. (Curr. Biol. 2002) 3
  2. Numerous microRNPs in neuronal cells containing novel microRNAs. (PMID: 12554860) Dostie J. … Dreyfuss G. (RNA 2003) 3
  3. Reduced accumulation of specific microRNAs in colorectal neoplasia. (PMID: 14573789) Michael M.Z. … James R.J. (Mol. Cancer Res. 2003) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  5. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3

Products for MIR15B Gene

Sources for MIR15B Gene

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