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Aliases for MIR15A Gene

Subcategory (RNA class) for MIR15A Gene


Quality Score for this RNA gene is


Aliases for MIR15A Gene

  • MicroRNA 15a 2 3 5
  • Hsa-Mir-15a 3
  • MiRNA15A 3
  • Mir-15a 3
  • MIRN15A 3

External Ids for MIR15A Gene

Previous HGNC Symbols for MIR15A Gene

  • MIRN15A

Previous GeneCards Identifiers for MIR15A Gene

  • GC13M049528
  • GC13M050624
  • GC13M050625
  • GC13M050601
  • GC13M049983

Summaries for MIR15A Gene

Entrez Gene Summary for MIR15A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR15A Gene

MIR15A (MicroRNA 15a) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

fRNAdb sequence ontologies for MIR15A Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR15A

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR15A Gene

Genomics for MIR15A Gene

Genomic Location for MIR15A Gene

50,049,119 bp from pter
50,049,201 bp from pter
83 bases
Minus strand

Genomic View for MIR15A Gene

Genes around MIR15A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR15A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR15A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR15A Gene

ORGUL Member Location for MIR15A Gene

ORGUL Member Location for MIR15A gene

No data available for Regulatory Elements for MIR15A Gene

Proteins for MIR15A Gene

Post-translational modifications for MIR15A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR15A Gene

Domains & Families for MIR15A Gene

Gene Families for MIR15A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR15A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR15A Gene

Function for MIR15A Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR15A Gene

Localization for MIR15A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR15A Gene

Pathways & Interactions for MIR15A Gene

SuperPathways for MIR15A Gene

SuperPathway Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR15A: view

Pathways by source for MIR15A Gene

1 KEGG pathway for MIR15A Gene

Interacting Proteins for MIR15A Gene

Gene Ontology (GO) - Biological Process for MIR15A Gene


No data available for SIGNOR curated interactions for MIR15A Gene

Drugs & Compounds for MIR15A Gene

No Compound Related Data Available

Transcripts for MIR15A Gene

fRNAdb Secondary structures for MIR15A Gene

  • FR269952

mRNA/cDNA for MIR15A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR15A Gene

No ASD Table

Relevant External Links for MIR15A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR15A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR15A Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR15A Gene

Orthologs for MIR15A Gene

Evolution for MIR15A Gene

Gene Tree for MIR15A (if available)
Gene Tree for MIR15A (if available)

No data available for Orthologs for MIR15A Gene

Paralogs for MIR15A Gene

No data available for Paralogs for MIR15A Gene

Variants for MIR15A Gene

Sequence variations from dbSNP and Humsavar for MIR15A Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
rs1001996172 -- 50,049,917(+) TAGAA(A/G)TTCTC intron-variant, upstream-variant-2KB
rs1003576601 -- 50,050,378(+) TGAGT(A/G)TTTTT intron-variant, upstream-variant-2KB
rs1005123286 -- 50,048,629(+) CTGTA(A/T)AGACA intron-variant, downstream-variant-500B
rs1005480841 -- 50,049,132(+) TTTTG(A/G)GGCAG intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1006341372 -- 50,051,128(+) AAATC(C/T)GTTTG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR15A Gene

Variant ID Type Subtype PubMed ID
esv3580637 CNV loss 25503493
nsv1035151 CNV loss 25217958
nsv1054415 CNV loss 25217958
nsv561618 CNV loss 21841781

Relevant External Links for MIR15A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR15A Gene

Disorders for MIR15A Gene

Relevant External Links for MIR15A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR15A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR15A Gene

Publications for MIR15A Gene

  1. miR-15 and miR-16 induce apoptosis by targeting BCL2. (PMID: 16166262) Cimmino A. … Croce C.M. (Proc. Natl. Acad. Sci. U.S.A. 2005) 3 22 64
  2. Role of miR-15a in intervertebral disc degeneration through targeting MAP3K9. (PMID: 28081468) Cai P. … Xia J. (Biomed. Pharmacother. 2017) 3 64
  3. miR-15a induces cell apoptosis by targeting BCL2L2 and BCL2 in HPV-positive hypopharyngeal squamous cell carcinoma. (PMID: 27573302) Lu W. … Lou W. (Oncol. Rep. 2016) 3 64
  4. MicroRNA-15a inhibits the growth and invasiveness of malignant melanoma and directly targets on CDCA4 gene. (PMID: 27492455) Alderman C. … Yang Y. (Tumour Biol. 2016) 3 64
  5. MicroRNA-15a Inhibits Proliferation and Induces Apoptosis in CNE1 Nasopharyngeal Carcinoma Cells. (PMID: 27458095) Zhu K. … Zheng G. (Oncol. Res. 2016) 3 64

Products for MIR15A Gene

Sources for MIR15A Gene

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