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Aliases for MIR155HG Gene

Subcategory (RNA class) for MIR155HG Gene

lncRNA

Quality Score for this RNA gene is

3

Aliases for MIR155HG Gene

  • MIR155 Host Gene 2 3
  • MicroRNA Host Gene 2 (Non-Protein Coding) 2 3
  • MIR155 Host Gene (Non-Protein Coding) 2 3
  • B-Cell Receptor Inducible 2 3
  • BIC Transcript 2 3
  • Non-Protein Coding RNA 172 2
  • Primary MIRN155 Transcript 3
  • NCRNA00172 3
  • MIRHG2 3
  • BIC 3

External Ids for MIR155HG Gene

Previous HGNC Symbols for MIR155HG Gene

  • MIRHG2

Previous GeneCards Identifiers for MIR155HG Gene

  • GC21P025873
  • GC21P026934
  • GC21P012337

Summaries for MIR155HG Gene

Entrez Gene Summary for MIR155HG Gene

  • MicroRNAs (miRNAs), such as miRNA155, are endogenous noncoding RNAs of about 22 nucleotides that regulate mRNAs by targeting them for cleavage or translational repression. The primary miRNA transcript containing the mature miRNA155 sequence, pri-miRNA155, is also referred to as BIC (Kluiver et al., 2005 [PubMed 16041695]).[supplied by OMIM, Mar 2008]

GeneCards Summary for MIR155HG Gene

MIR155HG (MIR155 Host Gene) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with MIR155HG include b-cell lymphomas and diffuse large b-cell lymphoma.

fRNAdb sequence ontologies for MIR155HG Gene - the ORGUL cluster for this gene includes several descriptions:

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • ncRNA: An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR155HG Gene

Genomics for MIR155HG Gene

Genomic Location for MIR155HG Gene

Start:
25,561,909 bp from pter
End:
25,575,168 bp from pter
Size:
13,260 bases
Orientation:
Plus strand

Genomic View for MIR155HG Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR155HG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR155HG Gene

No data available for Regulatory Elements for MIR155HG Gene

Proteins for MIR155HG Gene

Post-translational modifications for MIR155HG Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR155HG Gene

Domains for MIR155HG Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR155HG Gene

Function for MIR155HG Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR155HG Gene

Localization for MIR155HG Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR155HG Gene

Pathways for MIR155HG Gene

SuperPathways for MIR155HG Gene

No Data Available

Interacting Proteins for MIR155HG Gene

Gene Ontology (GO) - Biological Process for MIR155HG Gene

None

No data available for Pathways by source for MIR155HG Gene

Transcripts for MIR155HG Gene

mRNA/cDNA for MIR155HG Gene

Unigene Clusters for MIR155HG Gene

MIR155 host gene (non-protein coding):
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MIR155HG

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR155HG Gene

No ASD Table

Relevant External Links for MIR155HG Gene

GeneLoc Exon Structure for
MIR155HG
ECgene alternative splicing isoforms for
MIR155HG

Expression for MIR155HG Gene

mRNA expression in normal human tissues for MIR155HG Gene

SOURCE GeneReport for Unigene cluster for MIR155HG Gene Hs.697120

genes like me logo Genes that share expressions with MIR155HG: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR155HG Gene

Orthologs for MIR155HG Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR155HG Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-155 36
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-155 36
  • 95 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir155 36
  • 91 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-155 36
  • 48 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-155 36
  • 98 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-155 36
  • 92 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-155 36
  • 85 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-155 36
  • 56 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea csa-mir-155 36
  • 12 (a)
OneToOne
Species with no ortholog for MIR155HG:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR155HG Gene

ENSEMBL:
Gene Tree for MIR155HG (if available)
TreeFam:
Gene Tree for MIR155HG (if available)

Paralogs for MIR155HG Gene

No data available for Paralogs for MIR155HG Gene

Variants for MIR155HG Gene

Sequence variations from dbSNP and Humsavar for MIR155HG Gene

SNP ID Clin Chr 21 pos Sequence Context AA Info Type MAF
rs915860 -- 25,566,173(+) TTTCA(C/G)TAGAT intron-variant
rs928883 -- 25,571,713(+) CTAAT(A/G)TATAA intron-variant
rs972389 -- 25,567,997(+) AGGCA(A/T)ACGGA intron-variant
rs987195 -- 25,565,010(+) ATCCT(C/G)TATGT intron-variant
rs1547355 -- 25,575,427(+) CTAAC(A/C)CCTGG downstream-variant-500B

Relevant External Links for MIR155HG Gene

HapMap Linkage Disequilibrium report
MIR155HG

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MIR155HG Gene

Disorders for MIR155HG Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for MIR155HG Gene in MalaCards »

(3) Diseases for MIR155HG Gene including...

Relevant External Links for MIR155HG

Genetic Association Database (GAD)
MIR155HG
Human Genome Epidemiology (HuGE) Navigator
MIR155HG
genes like me logo Genes that share disorders with MIR155HG: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for MIR155HG Gene

Publications for MIR155HG Gene

  1. PTEN identified as important risk factor of chronic obstructive pulmonary disease. (PMID: 19625176) Hosgood H.D. … Lan Q. (Respir Med 2009) 3 48
  2. Genetic susceptibility to distinct bladder cancer subphenotypes. (PMID: 19692168) Guey L.T. … Malats N. (Eur. Urol. 2010) 3 48
  3. MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia. (PMID: 21296997) Vargova K. … Stopka T. (Blood 2011) 2 3
  4. Regulation of the MIR155 host gene in physiological and pathological processes. (PMID: 23246696) Elton T.S. … Parinandi N.L. (Gene 2013) 2 3
  5. Coordinated expression of microRNA-155 and predicted target genes in diffuse large B-cell lymphoma. (PMID: 18262046) Rai D. … Aguiar R.C. (Cancer Genet. Cytogenet. 2008) 23

Products for MIR155HG Gene

Sources for MIR155HG Gene

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