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Aliases for MIR155HG Gene

Subcategory (RNA class) for MIR155HG Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR155HG Gene

  • MIR155 Host Gene 2 3 5
  • MicroRNA Host Gene 2 (Non-Protein Coding) 2 3
  • B-Cell Receptor Inducible 2 3
  • BIC Transcript 2 3
  • MIR155 Host Gene (Non-Protein Coding) 2
  • Non-Protein Coding RNA 172 2
  • NCRNA00172 3
  • MIRHG2 3
  • BIC 3

External Ids for MIR155HG Gene

Previous HGNC Symbols for MIR155HG Gene

  • MIRHG2

Previous GeneCards Identifiers for MIR155HG Gene

  • GC21P025873
  • GC21P026934
  • GC21P012337

Summaries for MIR155HG Gene

Entrez Gene Summary for MIR155HG Gene

  • MicroRNAs (miRNAs), such as miRNA155, are endogenous noncoding RNAs of about 22 nucleotides that regulate mRNAs by targeting them for cleavage or translational repression. The primary miRNA transcript containing the mature miRNA155 sequence, pri-miRNA155, is also referred to as BIC (Kluiver et al., 2005 [PubMed 16041695]).[supplied by OMIM, Mar 2008]

GeneCards Summary for MIR155HG Gene

MIR155HG (MIR155 Host Gene) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR155HG include Periodic Limb Movement Disorder.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR155HG Gene

Genomics for MIR155HG Gene

Regulatory Elements for MIR155HG Gene

Enhancers for MIR155HG Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH21G025420 1.6 FANTOM5 Ensembl ENCODE 11.7 -138.6 -138567 4.8 HDGF PKNOX1 WRNIP1 FEZF1 ZNF302 ELK1 CBX5 ZNF143 FOS DEK MIR155HG MIR155 MRPL39 GC21M025430 GC21M025409
GH21G025456 1.5 FANTOM5 Ensembl ENCODE 11.3 -104.3 -104348 2.6 TBP TBL1XR1 BMI1 RFX5 RCOR1 RELB ETV6 IKZF2 CREM CBFB LINC00158 MIR155HG MIR155 MRPL39 GC21M025492
GH21G025486 1.2 FANTOM5 ENCODE 11.3 -74.7 -74681 0.8 PKNOX1 TBL1XR1 BMI1 ZBTB40 RELB ETV6 IKZF2 CREM SMAD5 CBFB MIR155HG MRPL39 GC21M025492 LINC00158
GH21G025461 1.2 FANTOM5 ENCODE 11.3 -99.6 -99629 1.7 PKNOX1 NFIB ZNF76 FEZF1 RAD21 ZSCAN5C RELB CREM EGR2 ZNF263 MIR155HG LINC00158 MIR155 MRPL39 GC21M025492
GH21G025369 0.8 Ensembl ENCODE 16 -191.8 -191806 2.2 JUND BHLHE40 FOS MAFK MIR155HG ENSG00000279534 GC21P025362
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR155HG on UCSC Golden Path with GeneCards custom track

Promoters for MIR155HG Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000140747 291 1201 TBP WRNIP1 RAD21 EGR1 ZNF143 ZNF207 FOS ETV6 CREM SMAD5
ENSR00000299950 1291 401 MXI1 TBL1XR1 SMAD5 WRNIP1 TRIM22 CHD1 POLR2A EED TARDBP STAT3

Genomic Location for MIR155HG Gene

Chromosome:
21
Start:
25,561,909 bp from pter
End:
25,575,168 bp from pter
Size:
13,260 bases
Orientation:
Plus strand

Genomic View for MIR155HG Gene

Genes around MIR155HG on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR155HG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR155HG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR155HG Gene

Proteins for MIR155HG Gene

Post-translational modifications for MIR155HG Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR155HG Gene

Domains & Families for MIR155HG Gene

Gene Families for MIR155HG Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR155HG: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR155HG Gene

Function for MIR155HG Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR155HG Gene

Localization for MIR155HG Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR155HG gene
Compartment Confidence
extracellular 2
nucleus 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MIR155HG Gene

Pathways & Interactions for MIR155HG Gene

SuperPathways for MIR155HG Gene

No Data Available

Interacting Proteins for MIR155HG Gene

Gene Ontology (GO) - Biological Process for MIR155HG Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR155HG Gene

Drugs & Compounds for MIR155HG Gene

No Compound Related Data Available

Transcripts for MIR155HG Gene

mRNA/cDNA for MIR155HG Gene

(3) Additional mRNA sequences :
(48) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MIR155HG Gene

MIR155 host gene (non-protein coding):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MIR155HG Gene

No ASD Table

Relevant External Links for MIR155HG Gene

GeneLoc Exon Structure for
MIR155HG
ECgene alternative splicing isoforms for
MIR155HG

Expression for MIR155HG Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR155HG Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR155HG Gene:

MIR155HG

SOURCE GeneReport for Unigene cluster for MIR155HG Gene:

Hs.697120

Evidence on tissue expression from TISSUES for MIR155HG Gene

  • Nervous system(2.1)
  • Bone(2)
genes like me logo Genes that share expression patterns with MIR155HG: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR155HG Gene

Orthologs for MIR155HG Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR155HG Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-155 35
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-155 35
  • 95 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-155 35
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir155 35
  • 91 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 85 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-155 35
  • 48 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-155 35
  • 92 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-155 35
  • 85 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-155 35
  • 56 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea csa-mir-155 35
  • 12 (a)
OneToOne
Species where no ortholog for MIR155HG was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR155HG Gene

ENSEMBL:
Gene Tree for MIR155HG (if available)
TreeFam:
Gene Tree for MIR155HG (if available)

Paralogs for MIR155HG Gene

No data available for Paralogs for MIR155HG Gene

Variants for MIR155HG Gene

Sequence variations from dbSNP and Humsavar for MIR155HG Gene

SNP ID Clin Chr 21 pos Sequence Context AA Info Type
rs1000011975 -- 25,568,064(+) TTCAG(C/T)GTTGA intron-variant, nc-transcript-variant
rs1000043691 -- 25,570,927(+) ACATA(C/T)TATGC intron-variant, nc-transcript-variant, downstream-variant-500B
rs1000118734 -- 25,560,523(+) GTGCC(C/G)CACCT upstream-variant-2KB
rs1000971287 -- 25,574,213(+) GTTTT(G/T)AAAGT intron-variant, nc-transcript-variant, downstream-variant-500B
rs1001061915 -- 25,568,919(+) GCTAT(G/T)TTCAA intron-variant

Relevant External Links for MIR155HG Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR155HG

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR155HG Gene

Disorders for MIR155HG Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR155HG Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
periodic limb movement disorder
  • nocturnal myoclonus
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR155HG

Genetic Association Database (GAD)
MIR155HG
Human Genome Epidemiology (HuGE) Navigator
MIR155HG
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR155HG
genes like me logo Genes that share disorders with MIR155HG: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR155HG Gene

Publications for MIR155HG Gene

  1. Regulation of the MIR155 host gene in physiological and pathological processes. (PMID: 23246696) Elton T.S. … Parinandi N.L. (Gene 2013) 2 3 64
  2. MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia. (PMID: 21296997) Vargova K. … Stopka T. (Blood 2011) 2 3 64
  3. Genetic susceptibility to distinct bladder cancer subphenotypes. (PMID: 19692168) Guey L.T. … Malats N. (Eur. Urol. 2010) 3 46 64
  4. PTEN identified as important risk factor of chronic obstructive pulmonary disease. (PMID: 19625176) Hosgood H.D. … Lan Q. (Respir Med 2009) 3 46 64
  5. MicroRNA-155 influences B-cell receptor signaling and associates with aggressive disease in chronic lymphocytic leukemia. (PMID: 24914134) Cui B. … Kipps T.J. (Blood 2014) 3 64

Products for MIR155HG Gene

Sources for MIR155HG Gene

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