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Aliases for MIR155HG Gene

Subcategory (RNA class) for MIR155HG Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR155HG Gene

  • MIR155 Host Gene 2 3 5
  • MicroRNA Host Gene 2 (Non-Protein Coding) 2 3
  • B-Cell Receptor Inducible 2 3
  • BIC Transcript 2 3
  • MIR155 Host Gene (Non-Protein Coding) 2
  • Non-Protein Coding RNA 172 2
  • NCRNA00172 3
  • MIRHG2 3
  • BIC 3

External Ids for MIR155HG Gene

Previous HGNC Symbols for MIR155HG Gene

  • MIRHG2

Previous GeneCards Identifiers for MIR155HG Gene

  • GC21P025873
  • GC21P026934
  • GC21P012337

Summaries for MIR155HG Gene

Entrez Gene Summary for MIR155HG Gene

  • This gene represents a microRNA host gene. The long RNA transcribed from this gene is expressed at high levels in lymphoma and may function as an oncogene. [provided by RefSeq, Dec 2017]

GeneCards Summary for MIR155HG Gene

MIR155HG (MIR155 Host Gene) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR155HG include Periodic Limb Movement Disorder.

Additional gene information for MIR155HG Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR155HG Gene

Genomics for MIR155HG Gene

GeneHancer (GH) Regulatory Elements for MIR155HG Gene

Promoters and enhancers for MIR155HG Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH21I025561 Promoter/Enhancer 1.5 Ensembl ENCODE dbSUPER 550.8 +0.8 773 3 SMAD1 RB1 BATF RAD21 KLF5 IRF4 ZNF207 ZNF143 ATF7 ETV6 MIR155HG MRPL39 GC21P025574
GH21I025559 Enhancer 1.1 FANTOM5 Ensembl ENCODE dbSUPER 550.8 -1.6 -1608 1 POLR2A CEBPA CEBPB MIR155HG LOC105372753
GH21I025420 Enhancer 1.3 FANTOM5 Ensembl ENCODE 11.7 -138.6 -138566 4.8 HDGF PKNOX1 SMAD1 BMI1 BATF IRF4 RAD21 ZNF143 ATF7 ETV6 MIR155HG MIR155 MRPL39 GC21M025430 LINC00158 GC21M025409
GH21I025456 Enhancer 1.3 FANTOM5 Ensembl ENCODE 11.3 -104.3 -104347 2.6 SMAD1 BMI1 BATF KLF5 IRF4 ATF7 ETV6 BCLAF1 IKZF2 RUNX3 LINC00158 MIR155HG MIR155 MRPL39 GC21M025492
GH21I025486 Enhancer 1.1 FANTOM5 ENCODE 11.3 -74.7 -74681 0.8 PKNOX1 SMAD1 BMI1 BATF KLF5 IRF4 ATF7 ETV6 BCLAF1 IKZF2 MIR155HG MRPL39 GC21M025492 LINC00158
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR155HG on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR155HG Gene

Genomic Locations for MIR155HG Gene
chr21:25,561,909-25,575,168
(GRCh38/hg38)
Size:
13,260 bases
Orientation:
Plus strand
chr21:26,934,221-26,947,480
(GRCh37/hg19)

Genomic View for MIR155HG Gene

Genes around MIR155HG on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR155HG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR155HG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR155HG Gene

Proteins for MIR155HG Gene

Post-translational modifications for MIR155HG Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR155HG Gene

Domains & Families for MIR155HG Gene

Gene Families for MIR155HG Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR155HG: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR155HG Gene

Function for MIR155HG Gene

Phenotypes From GWAS Catalog for MIR155HG Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR155HG Gene

Localization for MIR155HG Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR155HG gene
Compartment Confidence
extracellular 2
nucleus 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR155HG Gene

Pathways & Interactions for MIR155HG Gene

SuperPathways for MIR155HG Gene

No Data Available

Interacting Proteins for MIR155HG Gene

Gene Ontology (GO) - Biological Process for MIR155HG Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR155HG Gene

Drugs & Compounds for MIR155HG Gene

No Compound Related Data Available

Transcripts for MIR155HG Gene

mRNA/cDNA for MIR155HG Gene

(3) Additional mRNA sequences :
(48) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MIR155HG Gene

MIR155 host gene (non-protein coding):
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR155HG Gene

No ASD Table

Relevant External Links for MIR155HG Gene

GeneLoc Exon Structure for
MIR155HG
ECgene alternative splicing isoforms for
MIR155HG

Expression for MIR155HG Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR155HG Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR155HG Gene:

MIR155HG

SOURCE GeneReport for Unigene cluster for MIR155HG Gene:

Hs.697120

Evidence on tissue expression from TISSUES for MIR155HG Gene

  • Nervous system(2.1)
  • Bone(2)
genes like me logo Genes that share expression patterns with MIR155HG: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR155HG Gene

Orthologs for MIR155HG Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR155HG Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-155 34
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-155 34
  • 95 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-155 34
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir155 34
  • 91 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 85 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-155 34
  • 48 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-155 34
  • 92 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-155 34
  • 85 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-155 34
  • 56 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea csa-mir-155 34
  • 12 (a)
OneToOne
Species where no ortholog for MIR155HG was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR155HG Gene

ENSEMBL:
Gene Tree for MIR155HG (if available)
TreeFam:
Gene Tree for MIR155HG (if available)

Paralogs for MIR155HG Gene

No data available for Paralogs for MIR155HG Gene

Variants for MIR155HG Gene

Sequence variations from dbSNP and Humsavar for MIR155HG Gene

SNP ID Clin Chr 21 pos Variation AA Info Type
rs1000011975 -- 25,568,064(+) T/C intron_variant
rs1000043691 -- 25,570,927(+) T/C intron_variant
rs1000118734 -- 25,560,523(+) C/G upstream_transcript_variant
rs1000971287 -- 25,574,213(+) G/T non_coding_transcript_variant
rs1001061915 -- 25,568,919(+) T/G intron_variant

Additional Variant Information for MIR155HG Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR155HG

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR155HG Gene

Disorders for MIR155HG Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR155HG Gene - From: DISEASES

Disorder Aliases PubMed IDs
periodic limb movement disorder
  • nocturnal myoclonus
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR155HG

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with MIR155HG: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR155HG Gene

Publications for MIR155HG Gene

  1. Regulation of the MIR155 host gene in physiological and pathological processes. (PMID: 23246696) Elton TS … Parinandi NL (Gene 2013) 2 3 58
  2. MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia. (PMID: 21296997) Vargova K … Stopka T (Blood 2011) 2 3 58
  3. Genetic susceptibility to distinct bladder cancer subphenotypes. (PMID: 19692168) Guey LT … EPICURO/Spanish Bladder Cancer Study investigators (European urology 2010) 3 44 58
  4. PTEN identified as important risk factor of chronic obstructive pulmonary disease. (PMID: 19625176) Hosgood HD … Lan Q (Respiratory medicine 2009) 3 44 58
  5. Whole transcriptome analysis reveals dysregulated oncogenic lncRNAs in natural killer/T-cell lymphoma and establishes MIR155HG as a target of PRDM1. (PMID: 28468592) Baytak E … Küçük C (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017) 3 58

Products for MIR155HG Gene

Sources for MIR155HG Gene

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