Aliases
for MIR155HG gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
Subcategory (RNA class): bic
Quality score for this RNA gene is 5
| Aliases |
|---|
| MIR155 Host Gene (Non-Protein Coding)1 2 | | BIC1 2 | | MIRHG21 2 | | NCRNA001721 2 | | MicroRNA Host Gene 2 (Non-Protein Coding)1 |
| External Ids: | HGNC: 354601 | Entrez Gene: 1146142 | Ensembl: ENSG000002348837 |
Export aliases for MIR155HG gene to outside databasesPrevious GC identifers: GC21P025873 GC21P012337
|---|
Summaries
for MIR155HG gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MIR155HG:
MicroRNAs (miRNAs), such as miRNA155, are endogenous noncoding RNAs of about 22 nucleotides that regulate mRNAs bytargeting them for cleavage or translational repression. The primary miRNA transcript containing the mature miRNA155sequence, pri-miRNA155, is also referred to as BIC (Kluiver et al., 2005 (PubMed 16041695)).(supplied by OMIM, Mar2008)
fRNAdb sequence ontology for MIR155HG:
ncRNA - An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.
|
Genomic Views
for MIR155HG gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000021.8 NC_018932.1 NT_011512.11
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for MIR155HG
Other transcription factors
Search SABiosciences Chromatin IP Primers for MIR155HG
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MIR155HG |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Ensembl cytogenetic band: 21q21.3 HGNC cytogenetic band: 21q21.3MIR155HG Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 21 GeneLoc Exon Structure GeneLoc location for GC21P026934: view genomic region
(about GC identifiers)
Start:
|
26,934,221 bp from pter |
End:
|
26,947,480 bp from pter |
Size:
|
13,260 bases |
Orientation:
|
plus strand |
ORGUL member locations:
Legend (see complete legend)
 |
Proteins
for MIR155HG gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB: --
|
Protein
Domains /
Families
for MIR155HG gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| -- |
Function
for MIR155HG gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for MIR155HG | |  | Search LifeMap BioReagents cell lines for MIR155HG | In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MIR155HG |
Pathways & Interactions
for MIR155HG gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MIR155HG
|
Drugs & Compounds
for MIR155HG gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MIR155HG
Search CenterWatch for drugs/clinical trials and news about MIR155HG 
|
Transcripts
for MIR155HG gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
Unigene Cluster for MIR155HG: MIR155 host gene (non-protein coding) Hs.697120 [show with all ESTs]Unigene Representative Sequence: NR_0014581 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000456917(lincRNA)(uc002ylm.4)
Additional cDNA sequence: AF402776.1 EU375836.1 NR_001458.3 3 DOTS entries: DT.97796729 DT.209420 DT.121132937 24/48 AceView cDNA sequences (see all 48): NR_001458 CD676643 AA810953 AV713470 AW079379 CB528893 BX109321 AA382132 AV717582 BU939960 BU198987 AV715299 BG231557 CD641410 AI766963 AV716500 BG058739 AI281442 CD641131 AF402776 BG570624 AA283087 BG058661 AA282902
GeneLoc Exon Structure
|
Expression
for MIR155HG gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| Expression evidence for MIR155HG:RNAdb
MIR155HG expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGTCTTTAGT
About this image
Genevestigator expression for MIR155HG
SOURCE GeneReport for Unigene cluster: Hs.697120
SABiosciences Custom PCR Arrays for MIR155HG
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat MIR155HG | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MIR155HG | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MIR155HG | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MIR155HG |
Orthologs
for MIR155HG gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for MIR155HG (if available)
TreeFam Gene Tree for MIR155HG (if available) |
Paralogs
for MIR155HG gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for MIR155HG gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 21 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MIR155HG (26934221 - 26947480 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MIR155HG: -- | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for MIR155HG gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MIR155HG for disorders About GeneDecksing
13  diseases for MIR155HG: About MalaCardsdiffuse large b-cell lymphoma b-cell lymphomas chronic lymphocytic leukemia burkitt's lymphoma
lymphocytic leukemia kaposi's sarcoma hodgkin's lymphoma mediastinitis
rheumatoid arthritis pulmonary disease sarcoma arthritis
leukemia
Human Genome Epidemiology (HuGE) Navigator: MIR155HG (0 documents)
Export disorders for MIR155HG gene to outside databases
|
Publications
for MIR155HG gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MIR155HG gene, integrated from 9 sources (see all 26):
(articles sorted by number of sources associating them with MIR155HG) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Regulation of the MIR155 host gene in physiological an d pathological processes. (PubMed id 23246696)1, 3 Elton T.S....Parinandi N.L. (2012)
- MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia. (PubMed id 21296997)1, 3 Vargova K....Stopka T. (2011)
- Genetic susceptibility to distinct bladder cancer sub phenotypes. (PubMed id 19692168)1 Guey L.T....Malats N. (2010)
- PTEN identified as important risk factor of chronic o bstructive pulmonary disease. (PubMed id 19625176)1 Hosgood H.D....Lan Q. (2009)
- Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. (PubMed id 19170196)1 Shen M....Lan Q. (2009)
- BIC is processed efficiently to microRNA-155 in Burkitt lymphoma cells. (PubMed id 18354490)1 Zhang T....Tam W. (2008)
- B-cell receptor activation induces BIC/miR-155 expression through a conserved AP-1 element. (PubMed id 18048365)1 Yin Q....Flemington E. (2008)
- Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. (PubMed id 18676680)1 Hosgood H.D....Lan Q. (2008)
- Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis. (PubMed id 18383392)1 Stanczyk J....Kyburz D. (2008)
- Kaposi's sarcoma herpes virus taps into a host microRNA regulatory network. (PubMed id 18191785)1 McClure L.V. and Sullivan C.S. (2008)
|
External Searches for MIR155HG gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MIR155HG gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MIR155HG gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MIR155HG gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MIR155HG | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MIR155HG gene:
Search GeneIP for patents involving MIR155HG
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MIR155HG gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 |
| | | | |
 |
 |
|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MIR155HG | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MIR155HG | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MIR155HG | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MIR155HG | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MIR155HG | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MIR155HG |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MIR155HG |
|  |  |  |  | | | | Search ThermoFisher Antibodies for MIR155HG |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MIR155HG |
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