Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR155 Gene

Subcategory (RNA class) for MIR155 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR155 Gene

  • MicroRNA 155 2 3 5
  • Hsa-Mir-155 3
  • MiRNA155 3
  • Mir-155 3
  • MIRN155 3

External Ids for MIR155 Gene

ORGUL Members for MIR155 Gene

Previous HGNC Symbols for MIR155 Gene

  • MIRN155

Previous GeneCards Identifiers for MIR155 Gene

  • GC21P025871
  • GC21P026946

Summaries for MIR155 Gene

Entrez Gene Summary for MIR155 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR155 Gene

MIR155 (MicroRNA 155) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR155 include Primary Biliary Cholangitis. Among its related pathways are MicroRNAs in cancer.

Additional gene information for MIR155 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR155 Gene

Genomics for MIR155 Gene

Regulatory Elements for MIR155 Gene

Enhancers for MIR155 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH21H025456 1.5 FANTOM5 Ensembl ENCODE 11.1 -116.4 -116419 2 TBL1XR1 BMI1 BATF RFX5 ATF7 ETV6 RUNX3 CREM IKZF2 CBFB LINC00158 MIR155HG MIR155 MRPL39 GC21M025492
GH21H025420 1.4 FANTOM5 Ensembl ENCODE 11.6 -150.6 -150638 4 HDGF PKNOX1 TBL1XR1 SIN3A BMI1 BATF RAD21 ZNF143 ATF7 ETV6 MIR155HG MIR155 MRPL39 GC21M025430 GC21M025409
GH21H025461 1 FANTOM5 ENCODE 10.7 -111.7 -111700 1 PKNOX1 ZNF687 NR2F1 TRIM22 RELA ZNF217 POLR2A IKZF1 EED NBN MIR155HG LINC00158 MIR155 MRPL39 GC21M025492
GH21H025463 1.1 FANTOM5 ENCODE 9.7 -109.6 -109594 1 PKNOX1 BMI1 EBF1 BATF RELA POLR2A ZNF207 ATF7 ZSCAN29 ETV6 MIR155HG LINC00158 MIR155 MRPL39 GC21M025492
GH21H025459 0.6 FANTOM5 10.7 -114.5 -114472 0 PKNOX1 POLR2A BCL11A ATF7 MLLT1 CREM MIR155HG LINC00158 MIR155 GC21M025492
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR155 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR155 Gene

Chromosome:
21
Start:
25,573,980 bp from pter
End:
25,574,044 bp from pter
Size:
65 bases
Orientation:
Plus strand

Genomic View for MIR155 Gene

Genes around MIR155 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR155 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR155 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR155 Gene

Proteins for MIR155 Gene

Post-translational modifications for MIR155 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR155 Gene

Domains & Families for MIR155 Gene

Gene Families for MIR155 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR155: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR155 Gene

Function for MIR155 Gene

Phenotypes From GWAS Catalog for MIR155 Gene

Gene Ontology (GO) - Molecular Function for MIR155 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 20550618
genes like me logo Genes that share ontologies with MIR155: view

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR155
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR155 Gene

Localization for MIR155 Gene

Gene Ontology (GO) - Cellular Components for MIR155 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
GO:0048471 perinuclear region of cytoplasm ISS --
genes like me logo Genes that share ontologies with MIR155: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR155 Gene

Pathways & Interactions for MIR155 Gene

SuperPathways for MIR155 Gene

SuperPathway Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR155: view

Pathways by source for MIR155 Gene

1 KEGG pathway for MIR155 Gene

Interacting Proteins for MIR155 Gene

Gene Ontology (GO) - Biological Process for MIR155 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002696 positive regulation of leukocyte activation ISS --
GO:0002739 regulation of cytokine secretion involved in immune response ISS --
GO:0010613 positive regulation of cardiac muscle hypertrophy ISS --
GO:0010628 positive regulation of gene expression ISS --
GO:0010629 negative regulation of gene expression ISS --
genes like me logo Genes that share ontologies with MIR155: view

No data available for SIGNOR curated interactions for MIR155 Gene

Drugs & Compounds for MIR155 Gene

No Compound Related Data Available

Transcripts for MIR155 Gene

mRNA/cDNA for MIR155 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR155
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR155 Gene

No ASD Table

Relevant External Links for MIR155 Gene

GeneLoc Exon Structure for
MIR155
ECgene alternative splicing isoforms for
MIR155

Expression for MIR155 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR155 Gene:

MIR155
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR155 Gene

Orthologs for MIR155 Gene

Evolution for MIR155 Gene

ENSEMBL:
Gene Tree for MIR155 (if available)
TreeFam:
Gene Tree for MIR155 (if available)

No data available for Orthologs for MIR155 Gene

Paralogs for MIR155 Gene

No data available for Paralogs for MIR155 Gene

Variants for MIR155 Gene

Sequence variations from dbSNP and Humsavar for MIR155 Gene

SNP ID Clin Chr 21 pos Sequence Context AA Info Type
rs1000971287 -- 25,574,213(+) GTTTT(G/T)AAAGT intron-variant, nc-transcript-variant, downstream-variant-500B
rs1001572008 -- 25,572,220(+) TTCTA(C/T)AGTAT intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1002022760 -- 25,572,573(+) ATTTA(C/T)CTTCA intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1002858050 -- 25,572,874(+) TTTGG(A/T)AATTT intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1003543875 -- 25,571,999(+) TGGTT(G/T)CTTAG intron-variant, nc-transcript-variant, upstream-variant-2KB

Relevant External Links for MIR155 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR155

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR155 Gene

Disorders for MIR155 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR155 Gene - From: GeneCards

Disorder Aliases PubMed IDs
primary biliary cholangitis
  • primary biliary cirrhosis
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR155

Human Genome Epidemiology (HuGE) Navigator
MIR155
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR155
genes like me logo Genes that share disorders with MIR155: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR155 Gene

Publications for MIR155 Gene

  1. Predictive Effects of Circulating miR-221, miR-130a and miR-155 for Coronary Heart Disease: A Multi-Ethnic Study in China. (PMID: 28628920) Jia QW … Jia EZ (Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017) 3 60
  2. MiR-210 and miR-155 as potential diagnostic markers for pre-eclampsia pregnancies. (PMID: 28700503) Gan L … Xiao X (Medicine 2017) 3 60
  3. MicroRNA-155 regulates arsenite-induced malignant transformation by targeting Nrf2-mediated oxidative damage in human bronchial epithelial cells. (PMID: 28688901) Chen C … Zhang Z (Toxicology letters 2017) 3 60
  4. Association of microRNA-155, interleukin 17A, and proteinuria in preeclampsia. (PMID: 28471953) Yang X … Ding Y (Medicine 2017) 3 60
  5. Whole transcriptome analysis reveals dysregulated oncogenic lncRNAs in natural killer/T-cell lymphoma and establishes MIR155HG as a target of PRDM1. (PMID: 28468592) Baytak E … Küçük C (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017) 3 60

Products for MIR155 Gene

Sources for MIR155 Gene

Content
Loading form....