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Aliases for MIR155 Gene

Subcategory (RNA class) for MIR155 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR155 Gene

  • MicroRNA 155 2 3
  • MIR155 Host Gene 5
  • Hsa-Mir-155 3
  • MiRNA155 3
  • MIR155HG 5
  • Mir-155 3
  • MIRN155 3

External Ids for MIR155 Gene

Previous HGNC Symbols for MIR155 Gene

  • MIRN155

Previous GeneCards Identifiers for MIR155 Gene

  • GC21P025871
  • GC21P026946

Summaries for MIR155 Gene

Entrez Gene Summary for MIR155 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR155 Gene

MIR155 (MicroRNA 155) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR155 Gene

Genomics for MIR155 Gene

Regulatory Elements for MIR155 Gene

Enhancers for MIR155 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH21F025419 1.4 FANTOM5 Ensembl ENCODE 11.7 -139.1 -139057 5.8 HDGF PKNOX1 WRNIP1 FEZF1 ZNF302 ELK1 CBX5 ZNF143 FOS DEK MIR155 MIR155HG MRPL39 GC21M025430 GC21M025409
GH21F025584 0.5 FANTOM5 11.4 +22.8 22789 0.7 POLR2A MRPL39 MIR155 MIR155HG LINC00158 LINC00515
GH21F025510 0.4 ENCODE 11.4 -51.8 -51826 0.2 TBP MXI1 ZBED1 MAX JUNB EBF1 TBX21 RELA SP1 POLR2A MIR155 MIR155HG LINC00158 LOC105372753 GC21M025497
GH21F025508 0.4 ENCODE 11.4 -53.3 -53310 1.1 POLR2A MIR155 MIR155HG LINC00158 LOC105372753 GC21M025497
GH21F025486 1.5 FANTOM5 Ensembl ENCODE 11.3 -74.6 -74619 0.9 PKNOX1 TBL1XR1 BMI1 EBF1 ZBTB40 RELA EED ETV6 CREM CHD2 MIR155 MIR155HG MRPL39 GC21M025492 LINC00158
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR155 on UCSC Golden Path with GeneCards custom track

Promoters for MIR155 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000612089 791 2601 TBP TBL1XR1 WRNIP1 RAD21 EGR1 ZNF143 ETV6 FOS CREM SMAD5

Genomic Location for MIR155 Gene

Chromosome:
21
Start:
25,561,909 bp from pter
End:
25,575,168 bp from pter
Size:
13,260 bases
Orientation:
Plus strand

Genomic View for MIR155 Gene

Genes around MIR155 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR155 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR155 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR155 Gene

Proteins for MIR155 Gene

Post-translational modifications for MIR155 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR155 Gene

Domains & Families for MIR155 Gene

Gene Families for MIR155 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR155: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR155 Gene

Function for MIR155 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR155 Gene

Localization for MIR155 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR155 Gene

Pathways & Interactions for MIR155 Gene

SuperPathways for MIR155 Gene

SuperPathway Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR155: view

Pathways by source for MIR155 Gene

1 KEGG pathway for MIR155 Gene

Interacting Proteins for MIR155 Gene

Gene Ontology (GO) - Biological Process for MIR155 Gene

None

No data available for SIGNOR curated interactions for MIR155 Gene

Transcripts for MIR155 Gene

mRNA/cDNA for MIR155 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR155 Gene

No ASD Table

Relevant External Links for MIR155 Gene

GeneLoc Exon Structure for
MIR155
ECgene alternative splicing isoforms for
MIR155

Expression for MIR155 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR155 Gene:

MIR155
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR155 Gene

Orthologs for MIR155 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR155 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-155 35
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-155 35
  • 95 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-155 35
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir155 35
  • 91 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 85 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-155 35
  • 48 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-155 35
  • 92 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-155 35
  • 85 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-155 35
  • 56 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea csa-mir-155 35
  • 12 (a)
OneToOne
Species where no ortholog for MIR155 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR155 Gene

ENSEMBL:
Gene Tree for MIR155 (if available)
TreeFam:
Gene Tree for MIR155 (if available)

Paralogs for MIR155 Gene

No data available for Paralogs for MIR155 Gene

Variants for MIR155 Gene

Sequence variations from dbSNP and Humsavar for MIR155 Gene

SNP ID Clin Chr 21 pos Sequence Context AA Info Type
rs10531464 -- 25,572,128(+) ATATA(-/TAT)TTTTT intron-variant, nc-transcript-variant, upstream-variant-2KB
rs111648030 -- 25,573,605(+) AGAGC(A/G)GTTTT intron-variant, upstream-variant-2KB
rs112534472 -- 25,573,626(+) TTAAA(C/G)AAGAT intron-variant, upstream-variant-2KB
rs11295898 -- 25,573,530(+) ATCAG(-/A)AAAAA intron-variant, upstream-variant-2KB
rs115939101 -- 25,572,612(+) AGGGC(A/G)AGTTA intron-variant, nc-transcript-variant, upstream-variant-2KB

Relevant External Links for MIR155 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR155

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR155 Gene

Disorders for MIR155 Gene

Relevant External Links for MIR155

Human Genome Epidemiology (HuGE) Navigator
MIR155
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR155

No disorders were found for MIR155 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR155 Gene

Publications for MIR155 Gene

  1. Inhibition of the miR-155 target NIAM phenocopies the growth promoting effect of miR-155 in B-cell lymphoma. (PMID: 26497687) Slezak-Prochazka I. … van den Berg A. (Oncotarget 2016) 3 64
  2. MicroRNA-155 regulates host immune response to postviral bacterial pneumonia via IL-23/IL-17 pathway. (PMID: 26589478) Podsiad A. … Bhan U. (Am. J. Physiol. Lung Cell Mol. Physiol. 2016) 3 64
  3. Characterization of miR-146a and miR-155 in blood, tissue and cell lines of head and neck squamous cell carcinoma patients and their impact on cell proliferation and migration. (PMID: 26621153) Lerner C. … Schick B. (J. Cancer Res. Clin. Oncol. 2016) 3 64
  4. Role of Altered Expression of miR-146a, miR-155, and miR-122 in Pediatric Patients with Inflammatory Bowel Disease. (PMID: 26752469) BAcres N.J. … Veres G. (Inflamm. Bowel Dis. 2016) 3 64
  5. MicroRNA-155 enhances the activation of Wnt/I^-catenin signaling in colorectal carcinoma by suppressing HMG-box transcription factor 1. (PMID: 26780942) Wan Y.C. … Zhang B. (Mol Med Rep 2016) 3 64

Products for MIR155 Gene

Sources for MIR155 Gene

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