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Aliases for MIR155 Gene

Subcategory (RNA class) for MIR155 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR155 Gene

  • MicroRNA 155 2 3 5
  • Hsa-Mir-155 3
  • MiRNA155 3
  • Mir-155 3
  • MIRN155 3

External Ids for MIR155 Gene

ORGUL Members for MIR155 Gene

Previous HGNC Symbols for MIR155 Gene

  • MIRN155

Previous GeneCards Identifiers for MIR155 Gene

  • GC21P025871
  • GC21P026946

Summaries for MIR155 Gene

Entrez Gene Summary for MIR155 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR155 Gene

MIR155 (MicroRNA 155) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR155 include Primary Biliary Cholangitis. Among its related pathways are MicroRNAs in cancer.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR155 Gene

Genomics for MIR155 Gene

Regulatory Elements for MIR155 Gene

Enhancers for MIR155 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH21G025420 1.6 FANTOM5 Ensembl ENCODE 11.6 -150.6 -150638 4.8 HDGF PKNOX1 WRNIP1 FEZF1 ZNF302 ELK1 CBX5 ZNF143 FOS DEK MIR155HG MIR155 MRPL39 GC21M025430 GC21M025409
GH21G025456 1.5 FANTOM5 Ensembl ENCODE 11.1 -116.4 -116419 2.6 TBP TBL1XR1 BMI1 RFX5 RCOR1 RELB ETV6 IKZF2 CREM CBFB LINC00158 MIR155HG MIR155 MRPL39 GC21M025492
GH21G025461 1.2 FANTOM5 ENCODE 10.7 -111.7 -111700 1.7 PKNOX1 NFIB ZNF76 FEZF1 RAD21 ZSCAN5C RELB CREM EGR2 ZNF263 MIR155HG LINC00158 MIR155 MRPL39 GC21M025492
GH21G025463 1.1 FANTOM5 ENCODE 9.7 -109.6 -109594 1.0 TBP PKNOX1 BMI1 RELA ARID3A ZNF207 ZSCAN29 RELB ZNF600 ETV6 MIR155HG LINC00158 MIR155 MRPL39 GC21M025492
GH21G025459 0.7 FANTOM5 10.7 -114.5 -114472 0.2 PKNOX1 POLR2A TCF7 MLLT1 RELB TBX21 CREM MIR155HG LINC00158 MIR155 GC21M025492
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR155 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR155 Gene

Chromosome:
21
Start:
25,573,980 bp from pter
End:
25,574,044 bp from pter
Size:
65 bases
Orientation:
Plus strand

Genomic View for MIR155 Gene

Genes around MIR155 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR155 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR155 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR155 Gene

Proteins for MIR155 Gene

Post-translational modifications for MIR155 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR155 Gene

Domains & Families for MIR155 Gene

Gene Families for MIR155 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR155: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR155 Gene

Function for MIR155 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR155 Gene

Localization for MIR155 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR155 Gene

Pathways & Interactions for MIR155 Gene

SuperPathways for MIR155 Gene

SuperPathway Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR155: view

Pathways by source for MIR155 Gene

1 KEGG pathway for MIR155 Gene

Interacting Proteins for MIR155 Gene

Gene Ontology (GO) - Biological Process for MIR155 Gene

None

No data available for SIGNOR curated interactions for MIR155 Gene

Transcripts for MIR155 Gene

mRNA/cDNA for MIR155 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR155 Gene

No ASD Table

Relevant External Links for MIR155 Gene

GeneLoc Exon Structure for
MIR155
ECgene alternative splicing isoforms for
MIR155

Expression for MIR155 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR155 Gene:

MIR155
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR155 Gene

Orthologs for MIR155 Gene

Evolution for MIR155 Gene

ENSEMBL:
Gene Tree for MIR155 (if available)
TreeFam:
Gene Tree for MIR155 (if available)

No data available for Orthologs for MIR155 Gene

Paralogs for MIR155 Gene

No data available for Paralogs for MIR155 Gene

Variants for MIR155 Gene

Sequence variations from dbSNP and Humsavar for MIR155 Gene

SNP ID Clin Chr 21 pos Sequence Context AA Info Type
rs1000971287 -- 25,574,213(+) GTTTT(G/T)AAAGT intron-variant, nc-transcript-variant, downstream-variant-500B
rs1001572008 -- 25,572,220(+) TTCTA(C/T)AGTAT intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1002022760 -- 25,572,573(+) ATTTA(C/T)CTTCA intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1002858050 -- 25,572,874(+) TTTGG(A/T)AATTT intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1003543875 -- 25,571,999(+) TGGTT(G/T)CTTAG intron-variant, nc-transcript-variant, upstream-variant-2KB

Relevant External Links for MIR155 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR155

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR155 Gene

Disorders for MIR155 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR155 Gene - From: GeneCards

Disorder Aliases PubMed IDs
primary biliary cholangitis
  • familial primary biliary cirrhosis
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR155

Human Genome Epidemiology (HuGE) Navigator
MIR155
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR155
genes like me logo Genes that share disorders with MIR155: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR155 Gene

Publications for MIR155 Gene

  1. miR-155 promotes cutaneous wound healing through enhanced keratinocytes migration by MMP-2. (PMID: 28247149) Yang L. … Hu D. (J. Mol. Histol. 2017) 3 64
  2. Decreased Expression of Vitamin D Receptor Affects an Immune Response in Primary Biliary Cholangitis via the VDR-miRNA155-SOCS1 Pathway. (PMID: 28146070) Kempinska-Podhorodecka A. … Milkiewicz P. (Int J Mol Sci 2017) 3 64
  3. MicroRNAs 142-3p, miR-155 and miR-203 Are Deregulated in Gastric MALT Lymphomas Compared to Chronic Gastritis. (PMID: 28031239) FernA!ndez C. … Salar A. (Cancer Genomics Proteomics 2017) 3 64
  4. MicroRNA-155: a Novel Armamentarium Against Inflammatory Diseases. (PMID: 27981414) Xiaoyan W. … Guanwei F. (Inflammation 2017) 3 64
  5. MicroRNA-155 in serum-derived extracellular vesicles as a potential biomarker for hematologic malignancies - a short report. (PMID: 27761889) Caivano A. … Musto P. (Cell Oncol (Dordr) 2017) 3 64

Products for MIR155 Gene

Sources for MIR155 Gene

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