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Aliases for MIR1539 Gene

Subcategory (RNA class) for MIR1539 Gene


Quality Score for this RNA gene is


Aliases for MIR1539 Gene

  • MicroRNA 1539 2 3 5
  • Hsa-Mir-1539 3
  • MIRN1539 3

External Ids for MIR1539 Gene

Previous HGNC Symbols for MIR1539 Gene

  • MIRN1539

Previous GeneCards Identifiers for MIR1539 Gene

  • GC00U922935
  • GC18P045268
  • GC18P047013

Summaries for MIR1539 Gene

Entrez Gene Summary for MIR1539 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1539 Gene

MIR1539 (MicroRNA 1539) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1539 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1539 Gene

Genomics for MIR1539 Gene

GeneHancer (GH) Regulatory Elements for MIR1539 Gene

Promoters and enhancers for MIR1539 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH18I049485 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 0.8 +2.5 2493 8.4 MLX FEZF1 DMAP1 YY1 E2F8 ZNF143 SP3 NFYC ZFP41 SSRP1 C18orf32 GC18M049490 GC18M049512 GC18M049515 GC18M049516 GC18M049517 PIR54855 PIR56297 RPL17 RPL17-C18orf32
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1539 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1539 Gene

Genomic Locations for MIR1539 Gene
50 bases
Plus strand

Genomic View for MIR1539 Gene

Genes around MIR1539 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1539 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1539 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1539 Gene

Proteins for MIR1539 Gene

Post-translational modifications for MIR1539 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1539 Gene

Domains & Families for MIR1539 Gene

Gene Families for MIR1539 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1539: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1539 Gene

Function for MIR1539 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1539 Gene

Localization for MIR1539 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1539 Gene

Pathways & Interactions for MIR1539 Gene

SuperPathways for MIR1539 Gene

No Data Available

Interacting Proteins for MIR1539 Gene

Gene Ontology (GO) - Biological Process for MIR1539 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1539 Gene

Drugs & Compounds for MIR1539 Gene

No Compound Related Data Available

Transcripts for MIR1539 Gene

mRNA/cDNA for MIR1539 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1539 Gene

No ASD Table

Relevant External Links for MIR1539 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1539 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1539 Gene

mRNA differential expression in normal tissues according to GTEx for MIR1539 Gene

This gene is overexpressed in Testis (x11.3).

NURSA nuclear receptor signaling pathways regulating expression of MIR1539 Gene:

genes like me logo Genes that share expression patterns with MIR1539: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1539 Gene

Orthologs for MIR1539 Gene

Evolution for MIR1539 Gene

Gene Tree for MIR1539 (if available)
Gene Tree for MIR1539 (if available)

No data available for Orthologs for MIR1539 Gene

Paralogs for MIR1539 Gene

No data available for Paralogs for MIR1539 Gene

Variants for MIR1539 Gene

Sequence variations from dbSNP and Humsavar for MIR1539 Gene

SNP ID Clin Chr 18 pos Variation AA Info Type
rs1000460489 -- 49,486,700(+) T/C upstream_transcript_variant
rs1000599285 -- 49,487,575(+) T/C downstream_transcript_variant
rs1000651768 -- 49,487,383(+) C/T non_coding_transcript_variant
rs1000712280 -- 49,487,322(+) G/A upstream_transcript_variant
rs1000747061 -- 49,487,426(+) T/C downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1539 Gene

Variant ID Type Subtype PubMed ID
nsv1065279 CNV gain 25217958
nsv2294 CNV deletion 18451855
nsv978629 CNV duplication 23825009

Additional Variant Information for MIR1539 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1539 Gene

Disorders for MIR1539 Gene

Additional Disease Information for MIR1539

No disorders were found for MIR1539 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1539 Gene

Publications for MIR1539 Gene

  1. Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing. (PMID: 18524951) Azuma-Mukai A … Siomi MC (Proceedings of the National Academy of Sciences of the United States of America 2008) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR1539 Gene

Sources for MIR1539 Gene

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