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Aliases for MIR1538 Gene

Subcategory (RNA class) for MIR1538 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1538 Gene

  • MicroRNA 1538 2 3 5
  • Hsa-Mir-1538 3
  • MIRN1538 3

External Ids for MIR1538 Gene

Previous HGNC Symbols for MIR1538 Gene

  • MIRN1538

Previous GeneCards Identifiers for MIR1538 Gene

  • GC00U923100
  • GC16M068158

Summaries for MIR1538 Gene

Entrez Gene Summary for MIR1538 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1538 Gene

MIR1538 (MicroRNA 1538) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1538 Gene

Genomics for MIR1538 Gene

Regulatory Elements for MIR1538 Gene

Enhancers for MIR1538 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16G069393 1.9 FANTOM5 Ensembl ENCODE dbSUPER 11.9 +168.5 168525 7.4 HNRNPUL1 PKNOX1 FOXA2 MLX ZFP64 ARID4B SIN3A DMAP1 FEZF1 ZNF2 UTP4 CYB5B NIP7 TERF2 MIR1538 NFAT5 NQO1 LOC400541 GC16M069451
GH16G069528 1.8 FANTOM5 Ensembl ENCODE 12.5 +34.7 34662 4.6 CREB3L1 MLX ZFP64 DMAP1 YY1 ZNF143 SP3 TBX21 MEF2D SSRP1 SF3B3 CHTF8 NONOP1 NIP7 PDXDC2P EXOSC6 NPIPB14P MIR1538 NFAT5 PDPR
GH16G069402 2 FANTOM5 Ensembl ENCODE dbSUPER 11.2 +157.7 157691 11.5 PKNOX1 FOXA2 MLX ZFP64 ARID4B FEZF1 DMAP1 YY1 SLC30A9 ZNF302 PDPR LOC400541 NONOP1 TMED6 LOC100506083 UTP4 TERF2 MIR1538 NFAT5 NIP7
GH16G069479 1.7 FANTOM5 Ensembl ENCODE dbSUPER 11.4 +84.5 84544 4.0 HDAC1 FOXA2 ZNF133 KLF17 FEZF1 RAD21 TCF12 GATA2 KLF7 FOS CYB5B MIR1538 NFAT5 WWP2 ENSG00000252443 LOC100420066 SNTB2 GC16P069486 ENSG00000260108
GH16G069422 1.4 ENCODE dbSUPER 11.8 +141.2 141208 3.3 HDGF PKNOX1 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 PDPR CHTF8 MIR1538 NFAT5 NONOP1 NPIPB14P EXOSC6 CYB5B TMED6 CLEC18A
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1538 on UCSC Golden Path with GeneCards custom track

Promoters for MIR1538 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000087453 -532 3201 HDGF HNRNPUL1 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 YY1 SLC30A9

Genomic Location for MIR1538 Gene

Chromosome:
16
Start:
69,565,808 bp from pter
End:
69,565,868 bp from pter
Size:
61 bases
Orientation:
Minus strand

Genomic View for MIR1538 Gene

Genes around MIR1538 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1538 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1538 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1538 Gene

ORGUL Member Location for MIR1538 Gene

ORGUL Member Location for MIR1538 gene

Proteins for MIR1538 Gene

Post-translational modifications for MIR1538 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1538 Gene

Domains & Families for MIR1538 Gene

Gene Families for MIR1538 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1538: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1538 Gene

Function for MIR1538 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1538 Gene

Localization for MIR1538 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1538 Gene

Pathways & Interactions for MIR1538 Gene

SuperPathways for MIR1538 Gene

No Data Available

Interacting Proteins for MIR1538 Gene

Gene Ontology (GO) - Biological Process for MIR1538 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1538 Gene

Drugs & Compounds for MIR1538 Gene

No Compound Related Data Available

Transcripts for MIR1538 Gene

mRNA/cDNA for MIR1538 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1538 Gene

No ASD Table

Relevant External Links for MIR1538 Gene

GeneLoc Exon Structure for
MIR1538
ECgene alternative splicing isoforms for
MIR1538

Expression for MIR1538 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1538 Gene:

MIR1538
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1538 Gene

Orthologs for MIR1538 Gene

Evolution for MIR1538 Gene

ENSEMBL:
Gene Tree for MIR1538 (if available)
TreeFam:
Gene Tree for MIR1538 (if available)

No data available for Orthologs for MIR1538 Gene

Paralogs for MIR1538 Gene

No data available for Paralogs for MIR1538 Gene

Variants for MIR1538 Gene

Sequence variations from dbSNP and Humsavar for MIR1538 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000521919 -- 69,566,355(+) TCGCC(A/C)AAGTC upstream-variant-2KB, reference, synonymous-codon, utr-variant-5-prime
rs1000815203 -- 69,565,768(+) AGCCT(-/C)CCCCC downstream-variant-500B, upstream-variant-2KB
rs1000958080 -- 69,566,051(+) TCCCC(A/C)TTCCC upstream-variant-2KB, utr-variant-5-prime
rs1001322883 -- 69,566,177(+) GAGGA(A/G)GCAGC upstream-variant-2KB, utr-variant-5-prime
rs1001705909 -- 69,566,874(+) CAGCT(C/T)GTTTT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1538 Gene

Variant ID Type Subtype PubMed ID
nsv1852 CNV deletion 18451855

Relevant External Links for MIR1538 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1538

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1538 Gene

Disorders for MIR1538 Gene

Relevant External Links for MIR1538

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1538

No disorders were found for MIR1538 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1538 Gene

Publications for MIR1538 Gene

  1. Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing. (PMID: 18524951) Azuma-Mukai A. … Siomi M.C. (Proc. Natl. Acad. Sci. U.S.A. 2008) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1538 Gene

Sources for MIR1538 Gene

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