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Aliases for MIR1537 Gene

Subcategory (RNA class) for MIR1537 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1537 Gene

  • MicroRNA 1537 2 3 5
  • Hsa-Mir-1537 3
  • Mir-1537 3
  • MIRN1537 3

External Ids for MIR1537 Gene

Previous HGNC Symbols for MIR1537 Gene

  • MIRN1537

Previous GeneCards Identifiers for MIR1537 Gene

  • GC00U922956
  • GC01M234083
  • GC01M236016

Summaries for MIR1537 Gene

Entrez Gene Summary for MIR1537 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1537 Gene

MIR1537 (MicroRNA 1537) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1537 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1537 Gene

Genomics for MIR1537 Gene

Regulatory Elements for MIR1537 Gene

Enhancers for MIR1537 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H235876 1.4 FANTOM5 Ensembl ENCODE dbSUPER 10.9 -23.7 -23683 1 ZNF217 ZNF664 HDGF PKNOX1 JUNB ATF7 ATF2 MIR1537 LYST RNU5E-2P
GH01H235800 0.7 dbSUPER 11.7 +50.0 50001 5 SCRT1 PKNOX1 FOXA2 FOXA3 HLF CEBPB JUNB CEBPG PRDM2 SCRT2 MIR1537 RNU5E-2P LYST GNG4 ENSG00000258082 LYST-AS1 LDHAP2
GH01H235858 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -5.9 -5930 0 GFI1B MAFG NFE2 EMSY SP7 LYST GPR137B RNU5E-2P MIR1537
GH01H235843 1.3 Ensembl ENCODE dbSUPER 0.4 +9.5 9460 0 CTCF PKNOX1 FOXA2 ZNF2 RAD21 ZNF664 SMC3 ZNF143 PRDM10 ZNF654 B3GALNT2 LYST LYST-AS1 MIR1537
GH01H235857 0.7 Ensembl dbSUPER 0.7 -4.8 -4841 0 POLR2A ZSCAN4 LYST MIR1537 RNU5E-2P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1537 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1537 Gene

Chromosome:
1
Start:
235,853,000 bp from pter
End:
235,853,060 bp from pter
Size:
61 bases
Orientation:
Minus strand

Genomic View for MIR1537 Gene

Genes around MIR1537 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1537 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1537 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1537 Gene

ORGUL Member Location for MIR1537 Gene

ORGUL Member Location for MIR1537 gene

Proteins for MIR1537 Gene

Post-translational modifications for MIR1537 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1537 Gene

Domains & Families for MIR1537 Gene

Gene Families for MIR1537 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1537: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1537 Gene

Function for MIR1537 Gene

Phenotypes From GWAS Catalog for MIR1537 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR1537
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1537 Gene

Localization for MIR1537 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1537 Gene

Pathways & Interactions for MIR1537 Gene

SuperPathways for MIR1537 Gene

No Data Available

Interacting Proteins for MIR1537 Gene

Gene Ontology (GO) - Biological Process for MIR1537 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1537 Gene

Drugs & Compounds for MIR1537 Gene

No Compound Related Data Available

Transcripts for MIR1537 Gene

mRNA/cDNA for MIR1537 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR1537
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1537 Gene

No ASD Table

Relevant External Links for MIR1537 Gene

GeneLoc Exon Structure for
MIR1537
ECgene alternative splicing isoforms for
MIR1537

Expression for MIR1537 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1537 Gene:

MIR1537
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1537 Gene

Orthologs for MIR1537 Gene

Evolution for MIR1537 Gene

ENSEMBL:
Gene Tree for MIR1537 (if available)
TreeFam:
Gene Tree for MIR1537 (if available)

No data available for Orthologs for MIR1537 Gene

Paralogs for MIR1537 Gene

No data available for Paralogs for MIR1537 Gene

Variants for MIR1537 Gene

Sequence variations from dbSNP and Humsavar for MIR1537 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000995805 -- 235,854,925(+) GTCAC(C/T)CCAAT intron-variant, upstream-variant-2KB
rs1002134593 -- 235,853,848(+) CCTTT(C/T)AACAG intron-variant, upstream-variant-2KB
rs1002523356 -- 235,854,037(+) CTATC(C/T)CTGTT intron-variant, upstream-variant-2KB
rs1004239073 -- 235,853,820(+) AGTCA(C/T)ACTAA intron-variant, upstream-variant-2KB
rs1004660839 -- 235,853,679(+) CATTC(C/G/T)GGCTG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1537 Gene

Variant ID Type Subtype PubMed ID
dgv588n100 CNV gain 25217958
nsv832947 CNV gain 17160897

Relevant External Links for MIR1537 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1537

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1537 Gene

Disorders for MIR1537 Gene

Relevant External Links for MIR1537

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1537

No disorders were found for MIR1537 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1537 Gene

Publications for MIR1537 Gene

  1. The repertoire and features of human platelet microRNAs. (PMID: 23226537) Plé H … Provost P (PloS one 2012) 3 60
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  3. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 60
  4. Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing. (PMID: 18524951) Azuma-Mukai A … Siomi MC (Proceedings of the National Academy of Sciences of the United States of America 2008) 3 60
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR1537 Gene

Sources for MIR1537 Gene

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