Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR1537 Gene

Subcategory (RNA class) for MIR1537 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1537 Gene

  • MicroRNA 1537 2 3 5
  • Hsa-Mir-1537 3
  • Mir-1537 3
  • MIRN1537 3

External Ids for MIR1537 Gene

Previous HGNC Symbols for MIR1537 Gene

  • MIRN1537

Previous GeneCards Identifiers for MIR1537 Gene

  • GC00U922956
  • GC01M234083
  • GC01M236016

Summaries for MIR1537 Gene

Entrez Gene Summary for MIR1537 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1537 Gene

MIR1537 (MicroRNA 1537) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1537 Gene

Genomics for MIR1537 Gene

Regulatory Elements for MIR1537 Gene

Enhancers for MIR1537 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F235874 1.6 FANTOM5 Ensembl ENCODE 10.9 -26.5 -26516 9.6 HDGF PKNOX1 MLX ARID4B FEZF1 YY1 ZNF121 ZNF207 FOS SP5 LYST RNU6-968P MIR1537 RNU5E-2P
GH01F235855 1.4 FANTOM5 Ensembl ENCODE 0.8 -4.6 -4641 4.2 ZNF211 RAD21 YY1 POLR2A HNF4G NFE2 CREM NFE2L2 ZNF362 MTA2 LYST RNU6-968P GPR137B MIR1537 RNU5E-2P
GH01F235847 0.6 Ensembl 0.8 +4.4 4360 2.2 SMARCA4 ATF3 RNF2 ZNF512 MNT ZBTB40 ATF2 LYST MIR1537 LYST-AS1
GH01F235852 0.6 Ensembl 0.8 -1.0 -1041 2.6 SCRT1 MTA2 SCRT2 ZNF175 TBX21 SPI1 NR2F2 LYST MIR1537 RNU5E-2P
GH01F235841 1 Ensembl ENCODE 0.4 +10.5 10460 2.8 CTCF PKNOX1 ZNF2 RAD21 ZNF101 ZNF664 SMC3 PRDM10 ZNF654 ZNF362 RNU5E-2P B3GALNT2 LYST LYST-AS1 MIR1537
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1537 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1537 Gene

Chromosome:
1
Start:
235,853,000 bp from pter
End:
235,853,060 bp from pter
Size:
61 bases
Orientation:
Minus strand

Genomic View for MIR1537 Gene

Genes around MIR1537 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1537 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1537 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1537 Gene

ORGUL Member Location for MIR1537 Gene

ORGUL Member Location for MIR1537 gene

Proteins for MIR1537 Gene

Post-translational modifications for MIR1537 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1537 Gene

Domains & Families for MIR1537 Gene

Gene Families for MIR1537 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1537: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1537 Gene

Function for MIR1537 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1537 Gene

Localization for MIR1537 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1537 Gene

Pathways & Interactions for MIR1537 Gene

SuperPathways for MIR1537 Gene

No Data Available

Interacting Proteins for MIR1537 Gene

Gene Ontology (GO) - Biological Process for MIR1537 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1537 Gene

Transcripts for MIR1537 Gene

mRNA/cDNA for MIR1537 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1537 Gene

No ASD Table

Relevant External Links for MIR1537 Gene

GeneLoc Exon Structure for
MIR1537
ECgene alternative splicing isoforms for
MIR1537

Expression for MIR1537 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1537 Gene:

MIR1537
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1537 Gene

Orthologs for MIR1537 Gene

Evolution for MIR1537 Gene

ENSEMBL:
Gene Tree for MIR1537 (if available)
TreeFam:
Gene Tree for MIR1537 (if available)

No data available for Orthologs for MIR1537 Gene

Paralogs for MIR1537 Gene

No data available for Paralogs for MIR1537 Gene

Variants for MIR1537 Gene

Sequence variations from dbSNP and Humsavar for MIR1537 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs111688389 -- 235,852,723(+) ATTTT(A/C)AAATG intron-variant, downstream-variant-500B
rs113301642 -- 235,853,001(+) ACTTA(A/C/T)AACTG intron-variant, nc-transcript-variant
rs114113623 -- 235,854,646(+) TGTTG(C/T)GAATA intron-variant, upstream-variant-2KB
rs115051661 -- 235,854,488(+) CAGAA(A/T)AGCAC intron-variant, upstream-variant-2KB
rs116661564 -- 235,853,869(+) TTTCC(C/T)AAAAA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1537 Gene

Variant ID Type Subtype PubMed ID
dgv588n100 CNV gain 25217958
nsv832947 CNV gain 17160897

Relevant External Links for MIR1537 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1537

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1537 Gene

Disorders for MIR1537 Gene

Relevant External Links for MIR1537

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1537

No disorders were found for MIR1537 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1537 Gene

Publications for MIR1537 Gene

  1. The repertoire and features of human platelet microRNAs. (PMID: 23226537) PlAc H. … Provost P. (PLoS ONE 2012) 3 64
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  3. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3 64
  4. Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing. (PMID: 18524951) Azuma-Mukai A. … Siomi M.C. (Proc. Natl. Acad. Sci. U.S.A. 2008) 3 64
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1537 Gene

Sources for MIR1537 Gene

Content
Loading form....