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Aliases for MIR152 Gene

Subcategory (RNA class) for MIR152 Gene

miRNA

Quality Score for this RNA gene is

10

Aliases for MIR152 Gene

  • MicroRNA 152 2 3
  • MIRN152 3 6
  • Hsa-Mir-152 3

External Ids for MIR152 Gene

Previous Symbols for MIR152 Gene

  • MIRN152

Summaries for MIR152 Gene

Entrez Gene Summary for MIR152 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR152 Gene

MIR152 (MicroRNA 152) is a RNA Gene, and belongs to miRNA RNA class. Among its related pathways are MicroRNAs in cancer.

fRNAdb sequence ontologies for MIR152 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR152

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR152 Gene

Genomics for MIR152 Gene

Genomic Location for MIR152 Gene

Start:
48,037,154 bp from pter
End:
48,037,262 bp from pter
Size:
109 bases
Orientation:
Minus strand

Genomic View for MIR152 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR152 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR152 Gene

ORGUL Member Location for MIR152 Gene

ORGUL Member Location for MIR152 gene

No data available for Regulatory Elements for MIR152 Gene

Proteins for MIR152 Gene

Post-translational modifications for MIR152 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR152 Gene

Domains for MIR152 Gene

Gene Families for MIR152 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR152: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR152 Gene

Function for MIR152 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR152 Gene

Localization for MIR152 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR152 Gene

Pathways for MIR152 Gene

SuperPathways for MIR152 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR152: view

Pathways by source for MIR152 Gene

1 KEGG pathway for MIR152 Gene

Interacting Proteins for MIR152 Gene

Gene Ontology (GO) - Biological Process for MIR152 Gene

None

Transcripts for MIR152 Gene

fRNAdb Secondary structures for MIR152 Gene

  • hsa-miR-152-5p_MIMAT0026479_Homo_sapiens_miR-152-5p_mature

mRNA/cDNA for MIR152 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR152 Gene

No ASD Table

Relevant External Links for MIR152 Gene

GeneLoc Exon Structure for
MIR152
ECgene alternative splicing isoforms for
MIR152

Expression for MIR152 Gene

mRNA expression in normal human tissues for MIR152 Gene

genes like me logo Genes that share expressions with MIR152: view

Orthologs for MIR152 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR152 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-152 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-152 37
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-152 37
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir152 37
  • 95 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-152 37
  • 90 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-152 37
  • 79 (a)
OneToOne
Species with no ortholog for MIR152:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR152 Gene

ENSEMBL:
Gene Tree for MIR152 (if available)
TreeFam:
Gene Tree for MIR152 (if available)

Paralogs for MIR152 Gene

No data available for Paralogs for MIR152 Gene

Variants for MIR152 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR152 Gene

Variant ID Type Subtype PubMed ID
nsv469808 CNV Complex 16826518

Relevant External Links for MIR152 Gene

HapMap Linkage Disequilibrium report
MIR152

No data available for Sequence variations from dbSNP and Humsavar for MIR152 Gene

Disorders for MIR152 Gene

No disorders were found for MIR152 Gene.

No data available for UniProtKB/Swiss-Prot for MIR152 Gene

Publications for MIR152 Gene

  1. Identification of tissue-specific microRNAs from mouse. (PMID: 12007417) Lagos-Quintana M. … Tuschl T. (Curr. Biol. 2002) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. Patterns of known and novel small RNAs in human cervical cancer. (PMID: 17616659) Lui W.O. … Fire A. (Cancer Res. 2007) 3
  5. Analysis of deep sequencing microRNA expression profile from human embryonic stem cells derived mesenchymal stem cells reveals possible role of let-7 microRNA family in downstream targeting of hepatic nuclear factor 4 alpha. (PMID: 20158877) Koh W. … Tanavde V. (BMC Genomics 2010) 3

Products for MIR152 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR152
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR152
    • Block miRNA regulation of MIR152 using miScript Target Protectors

    Sources for MIR152 Gene

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