Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR152 Gene

Subcategory (RNA class) for MIR152 Gene


Quality Score for this RNA gene is


Aliases for MIR152 Gene

  • MicroRNA 152 2 3 5
  • Hsa-Mir-152 3
  • Mir-152 3
  • MIRN152 3

External Ids for MIR152 Gene

Previous HGNC Symbols for MIR152 Gene

  • MIRN152

Previous GeneCards Identifiers for MIR152 Gene

  • GC17U901085
  • GC17M043473
  • GC17M046114

Summaries for MIR152 Gene

Entrez Gene Summary for MIR152 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR152 Gene

MIR152 (MicroRNA 152) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR152 include Undifferentiated Pleomorphic Sarcoma. Among its related pathways are MicroRNAs in cancer.

fRNAdb sequence ontologies for MIR152 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR152

Additional gene information for MIR152 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR152 Gene

Genomics for MIR152 Gene

GeneHancer (GH) Regulatory Elements for MIR152 Gene

Promoters and enhancers for MIR152 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I048036 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE 550.8 -0.3 -334 1.8 HDGF PKNOX1 ARID4B SIN3A BMI1 THRB ZNF48 RAD21 ELK1 ZNF207 COPZ2 GC17P048037 MIR152 ENSG00000263412 PRR15L SNX11 SCRN2 TBX21
GH17I047970 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 10.1 +65.9 65925 2.1 CLOCK ZFP64 YBX1 DMAP1 YY1 E2F8 ZNF143 SP3 NFYC SSRP1 CDK5RAP3 SP2 ENSG00000266601 KPNB1 SCRN2 MRPL45P2 PNPO EFCAB13 PRR15L SP2-AS1
GH17I048106 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 10.8 -70.7 -70705 2.6 HDGF PKNOX1 SMAD1 ARID4B SIN3A YBX1 ZBTB7B YY1 POLR2B E2F8 SNX11 COPZ2 ENSG00000266601 KPNB1 EFCAB13 NFE2L1 MIR152 ENSG00000263412 ENSG00000263766 SP2
GH17I048011 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 11.3 +23.8 23816 4.3 HDGF PKNOX1 CLOCK ARNT SIN3A ZNF2 ZBTB7B E2F8 ZNF207 ZNF143 SP2 MRPL45P2 SCRN2 PRR15L ENSG00000264701 UBE2Z EFCAB13 RPS2P47 COPZ2 CDK5RAP3
GH17I047964 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 10 +70.2 70217 4.6 ELF3 MLX ARID4B RAD21 YY1 ZNF121 FOS THAP11 RXRA SP5 CDK5RAP3 SCRN2 PNPO PRR15L SKAP1 SP2-AS1 SP2 MIR152 COPZ2 SNX11
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR152 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR152 Gene

Genomic Locations for MIR152 Gene
87 bases
Minus strand

Genomic View for MIR152 Gene

Genes around MIR152 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR152 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR152 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR152 Gene

ORGUL Member Location for MIR152 Gene

ORGUL Member Location for MIR152 gene

Proteins for MIR152 Gene

Post-translational modifications for MIR152 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR152 Gene

Domains & Families for MIR152 Gene

Gene Families for MIR152 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR152: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR152 Gene

Function for MIR152 Gene

Phenotypes From GWAS Catalog for MIR152 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR152 Gene

Localization for MIR152 Gene

Gene Ontology (GO) - Cellular Components for MIR152 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR152: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR152 Gene

Pathways & Interactions for MIR152 Gene

SuperPathways for MIR152 Gene

SuperPathway Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR152: view

Pathways by source for MIR152 Gene

1 KEGG pathway for MIR152 Gene

Interacting Proteins for MIR152 Gene

Gene Ontology (GO) - Biological Process for MIR152 Gene


No data available for SIGNOR curated interactions for MIR152 Gene

Drugs & Compounds for MIR152 Gene

No Compound Related Data Available

Transcripts for MIR152 Gene

fRNAdb Secondary structures for MIR152 Gene

  • hsa-miR-152-5p_MIMAT0026479_Homo_sapiens_miR-152-5p_mature

mRNA/cDNA for MIR152 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR152 Gene

No ASD Table

Relevant External Links for MIR152 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR152 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR152 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR152 Gene:

genes like me logo Genes that share expression patterns with MIR152: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR152 Gene

Orthologs for MIR152 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR152 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-152 34
  • 99 (a)
(Bos Taurus)
Mammalia bta-mir-152 34
  • 98 (a)
(Mus musculus)
Mammalia Mir152 34
  • 95 (a)
(Canis familiaris)
Mammalia cfa-mir-152 34
  • 94 (a)
(Monodelphis domestica)
Mammalia mdo-mir-152 34
  • 90 (a)
(Danio rerio)
Actinopterygii dre-mir-152 34
  • 79 (a)
Species where no ortholog for MIR152 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR152 Gene

Gene Tree for MIR152 (if available)
Gene Tree for MIR152 (if available)

Paralogs for MIR152 Gene

No data available for Paralogs for MIR152 Gene

Variants for MIR152 Gene

Sequence variations from dbSNP and Humsavar for MIR152 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1003604651 -- 48,037,395(-) T/G upstream_transcript_variant
rs1004065050 -- 48,038,097(-) C/G upstream_transcript_variant
rs1007796613 -- 48,038,185(-) T/C upstream_transcript_variant
rs1008151725 -- 48,037,932(-) T/C upstream_transcript_variant
rs1008343103 -- 48,037,592(-) G/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR152 Gene

Variant ID Type Subtype PubMed ID
nsv469808 CNV loss 16826518

Additional Variant Information for MIR152 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR152 Gene

Disorders for MIR152 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR152 Gene - From: GeneCards

Disorder Aliases PubMed IDs
undifferentiated pleomorphic sarcoma
  • malignant fibrohistiocytic tumors
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR152

genes like me logo Genes that share disorders with MIR152: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR152 Gene

Publications for MIR152 Gene

  1. Identification of tissue-specific microRNAs from mouse. (PMID: 12007417) Lagos-Quintana M … Tuschl T (Current biology : CB 2002) 1 3 58
  2. MiR-148a and miR-152 reduce tamoxifen resistance in ER+ breast cancer via downregulating ALCAM. (PMID: 28063929) Chen MJ … Shen CJ (Biochemical and biophysical research communications 2017) 3 58
  3. Reciprocal Regulation Between miR-148a/152 and DNA Methyltransferase 1 Is Associated with Hyperhomocysteinemia-Accelerated Atherosclerosis. (PMID: 28472596) Yang A … Jiang Y (DNA and cell biology 2017) 3 58
  4. The role of the miR-148/-152 family in physiology and disease. (PMID: 28880997) Friedrich M … Seliger B (European journal of immunology 2017) 3 58
  5. miR-152 down-regulation is associated with MET up-regulation in leiomyosarcoma and undifferentiated pleomorphic sarcoma. (PMID: 27900663) Pazzaglia L … Benassi MS (Cellular oncology (Dordrecht) 2017) 3 58

Products for MIR152 Gene

Sources for MIR152 Gene

Loading form....