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Aliases for MIR151B Gene

Subcategory (RNA class) for MIR151B Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR151B Gene

  • MicroRNA 151b 2 3 5
  • Hsa-Mir-151b 3

External Ids for MIR151B Gene

Previous GeneCards Identifiers for MIR151B Gene

  • GC14U901275
  • GC14M100576

Summaries for MIR151B Gene

Entrez Gene Summary for MIR151B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR151B Gene

MIR151B (MicroRNA 151b) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR151B Gene

Genomics for MIR151B Gene

Regulatory Elements for MIR151B Gene

Enhancers for MIR151B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14G100102 1.5 Ensembl ENCODE dbSUPER 0.7 +3.6 3636 7.0 WRNIP1 SIN3A ZNF2 ZNF48 GLIS2 GATA2 ZNF143 FOS ZNF263 REST EVL ENSG00000258666 MIR151B PIR41188
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR151B on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR151B Gene

Chromosome:
14
Start:
100,109,419 bp from pter
End:
100,109,514 bp from pter
Size:
96 bases
Orientation:
Minus strand

Genomic View for MIR151B Gene

Genes around MIR151B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR151B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR151B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR151B Gene

Proteins for MIR151B Gene

Post-translational modifications for MIR151B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR151B Gene

Domains & Families for MIR151B Gene

Gene Families for MIR151B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR151B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR151B Gene

Function for MIR151B Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR151B Gene

Localization for MIR151B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR151B Gene

Pathways & Interactions for MIR151B Gene

SuperPathways for MIR151B Gene

No Data Available

Interacting Proteins for MIR151B Gene

Gene Ontology (GO) - Biological Process for MIR151B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR151B Gene

Transcripts for MIR151B Gene

mRNA/cDNA for MIR151B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR151B Gene

No ASD Table

Relevant External Links for MIR151B Gene

GeneLoc Exon Structure for
MIR151B
ECgene alternative splicing isoforms for
MIR151B

Expression for MIR151B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR151B Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR151B Gene:

MIR151B
genes like me logo Genes that share expression patterns with MIR151B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR151B Gene

Orthologs for MIR151B Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR151B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 92 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 28 (a)
OneToMany
-- 35
  • 25 (a)
OneToMany
-- 35
  • 23 (a)
OneToMany
-- 35
  • 18 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 26 (a)
ManyToMany
-- 35
  • 26 (a)
ManyToMany
-- 35
  • 25 (a)
ManyToMany
-- 35
  • 23 (a)
ManyToMany
-- 35
  • 16 (a)
ManyToMany
-- 35
  • 15 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 25 (a)
OneToOne
Species where no ortholog for MIR151B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR151B Gene

ENSEMBL:
Gene Tree for MIR151B (if available)
TreeFam:
Gene Tree for MIR151B (if available)

Paralogs for MIR151B Gene

No data available for Paralogs for MIR151B Gene

Variants for MIR151B Gene

Sequence variations from dbSNP and Humsavar for MIR151B Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1000327153 -- 100,109,081(+) TGAAG(A/G)CTGTG intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1000855989 -- 100,110,682(+) CGGGT(G/T)CCCCT intron-variant, upstream-variant-2KB
rs1002768547 -- 100,111,074(+) CACCC(A/G)CTCCA intron-variant, upstream-variant-2KB
rs1003035364 -- 100,110,392(+) AAAGG(A/T)AACTA intron-variant, upstream-variant-2KB
rs1003636299 -- 100,111,452(+) GTGCC(C/T)GGCCA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR151B Gene

Variant ID Type Subtype PubMed ID
nsv527130 CNV loss 19592680
nsv832874 CNV loss 17160897

Relevant External Links for MIR151B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR151B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR151B Gene

Disorders for MIR151B Gene

Relevant External Links for MIR151B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR151B

No disorders were found for MIR151B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR151B Gene

Publications for MIR151B Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
  3. Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. (PMID: 16954537) Berezikov E. … Cuppen E. (Genome Res. 2006) 3 64

Products for MIR151B Gene

Sources for MIR151B Gene

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