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Aliases for MIR148B Gene

Subcategory (RNA class) for MIR148B Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR148B Gene

  • MicroRNA 148b 2 3
  • MIRN148B 3 6
  • Hsa-Mir-148b 3
  • Mir-148b 3

External Ids for MIR148B Gene

ORGUL Members for MIR148B Gene

Previous HGNC Symbols for MIR148B Gene

  • MIRN148B

Previous GeneCards Identifiers for MIR148B Gene

  • GC12P053019
  • GC12P054731

Summaries for MIR148B Gene

Entrez Gene Summary for MIR148B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR148B Gene

MIR148B (MicroRNA 148b) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR148B Gene

Genomics for MIR148B Gene

Genomic Location for MIR148B Gene

Start:
54,337,208 bp from pter
End:
54,337,316 bp from pter
Size:
109 bases
Orientation:
Plus strand

Genomic View for MIR148B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR148B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR148B Gene

No data available for Regulatory Elements for MIR148B Gene

Proteins for MIR148B Gene

Post-translational modifications for MIR148B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR148B Gene

Domains for MIR148B Gene

Gene Families for MIR148B Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR148B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR148B Gene

Function for MIR148B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR148B Gene

Localization for MIR148B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR148B Gene

Pathways for MIR148B Gene

SuperPathways for MIR148B Gene

No Data Available

Interacting Proteins for MIR148B Gene

Gene Ontology (GO) - Biological Process for MIR148B Gene

None

No data available for Pathways by source for MIR148B Gene

Transcripts for MIR148B Gene

mRNA/cDNA for MIR148B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MIR148B

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR148B Gene

No ASD Table

Relevant External Links for MIR148B Gene

GeneLoc Exon Structure for
MIR148B
ECgene alternative splicing isoforms for
MIR148B

Expression for MIR148B Gene

mRNA expression in normal human tissues for MIR148B Gene

genes like me logo Genes that share expressions with MIR148B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR148B Gene

Orthologs for MIR148B Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR148B Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-148b 36
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-148b 36
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir148b 36
  • 94 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-148b 36
  • 100 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-148b 36
  • 89 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-148 36
  • 72 (a)
ManyToMany
Species with no ortholog for MIR148B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR148B Gene

ENSEMBL:
Gene Tree for MIR148B (if available)
TreeFam:
Gene Tree for MIR148B (if available)

Paralogs for MIR148B Gene

No data available for Paralogs for MIR148B Gene

Variants for MIR148B Gene

Relevant External Links for MIR148B Gene

HapMap Linkage Disequilibrium report
MIR148B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR148B Gene

Disorders for MIR148B Gene

No disorders were found for MIR148B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR148B Gene

Publications for MIR148B Gene

  1. Vertebrate microRNA genes. (PMID: 12624257) Lim L.P. … Bartel D.P. (Science 2003) 3
  2. Identification of many microRNAs that copurify with polyribosomes in mammalian neurons. (PMID: 14691248) Kim J. … Ruvkun G. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3
  3. New human and mouse microRNA genes found by homology search. (PMID: 15634332) Weber M.J. (FEBS J. 2005) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  5. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3

Products for MIR148B Gene

Sources for MIR148B Gene

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