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Aliases for MIR148A Gene

Subcategory (RNA class) for MIR148A Gene


Quality Score for this RNA gene is


Aliases for MIR148A Gene

  • MicroRNA 148a 2 3 5
  • MicroRNA 148 2 3
  • Hsa-Mir-148a 3
  • Hsa-Mir-148 3
  • Mir-148a 3
  • MIRN148A 3
  • MIRN148 3

External Ids for MIR148A Gene

Previous HGNC Symbols for MIR148A Gene

  • MIRN148
  • MIRN148A

Previous GeneCards Identifiers for MIR148A Gene

  • GC07M025957
  • GC07M025990

Summaries for MIR148A Gene

Entrez Gene Summary for MIR148A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR148A Gene

MIR148A (MicroRNA 148a) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR148A Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR148A

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR148A Gene

Genomics for MIR148A Gene

Regulatory Elements for MIR148A Gene

Enhancers for MIR148A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around MIR148A on UCSC Golden Path with GeneCards custom track

Promoters for MIR148A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for MIR148A Gene

25,949,919 bp from pter
25,949,986 bp from pter
68 bases
Minus strand

Genomic View for MIR148A Gene

Genes around MIR148A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR148A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR148A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR148A Gene

Proteins for MIR148A Gene

Post-translational modifications for MIR148A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR148A Gene

Domains & Families for MIR148A Gene

Gene Families for MIR148A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR148A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR148A Gene

Function for MIR148A Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR148A Gene

Localization for MIR148A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR148A Gene

Pathways & Interactions for MIR148A Gene

SuperPathways for MIR148A Gene

No Data Available

Interacting Proteins for MIR148A Gene

Gene Ontology (GO) - Biological Process for MIR148A Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR148A Gene

Drugs & Compounds for MIR148A Gene

No Compound Related Data Available

Transcripts for MIR148A Gene

fRNAdb Secondary structures for MIR148A Gene

  • hsa-miR-148a-5p_MIMAT0004549_Homo_sapiens_miR-148a-5p_mature
  • hsa-mir-148a_MI0000253_Homo_sapiens_miR-148a_stem-loop_hairpin

mRNA/cDNA for MIR148A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR148A Gene

No ASD Table

Relevant External Links for MIR148A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR148A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR148A Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR148A Gene

Orthologs for MIR148A Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR148A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-148a 35
  • 99 (a)
(Canis familiaris)
Mammalia cfa-mir-148a 35
  • 99 (a)
(Mus musculus)
Mammalia Mir148a 35
  • 66 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-148 35
  • 74 (a)
(Pan troglodytes)
Mammalia ptr-mir-148a 35
  • 100 (a)
(Gallus gallus)
Aves gga-mir-148a 35
  • 88 (a)
(Anolis carolinensis)
Reptilia aca-mir-148a 35
  • 63 (a)
(Danio rerio)
Actinopterygii BX546447.1 35
  • 67 (a)
Species where no ortholog for MIR148A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR148A Gene

Gene Tree for MIR148A (if available)
Gene Tree for MIR148A (if available)

Paralogs for MIR148A Gene

No data available for Paralogs for MIR148A Gene

Variants for MIR148A Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR148A Gene

Variant ID Type Subtype PubMed ID
nsv1126776 CNV deletion 24896259
nsv606432 CNV gain 21841781
nsv7393 OTHER inversion 18451855

Relevant External Links for MIR148A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR148A Gene

Disorders for MIR148A Gene

Relevant External Links for MIR148A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR148A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR148A Gene

Publications for MIR148A Gene

  1. Identification of human fetal liver miRNAs by a novel method. (PMID: 15978578) Fu H. … Zheng X. (FEBS Lett. 2005) 1 3 65
  2. Identification of tissue-specific microRNAs from mouse. (PMID: 12007417) Lagos-Quintana M. … Tuschl T. (Curr. Biol. 2002) 1 3 65
  3. Differentiation therapy for hepatocellular carcinoma: Multifaceted effects of miR-148a on tumor growth and phenotype and liver fibrosis. (PMID: 26599259) Jung K.H. … Beretta L. (Hepatology 2016) 3 65
  4. miR-148a-3p overexpression contributes to glomerular cell proliferation by targeting PTEN in lupus nephritis. (PMID: 26791485) Qingjuan L. … Shuxia L. (Am. J. Physiol., Cell Physiol. 2016) 3 65
  5. DNMT-dependent suppression of microRNA regulates the induction of GBM tumor-propagating phenotype by Oct4 and Sox2. (PMID: 25328136) Lopez-Bertoni H. … Li Y. (Oncogene 2015) 3 65

Products for MIR148A Gene

Sources for MIR148A Gene

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