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Aliases for MIR148A Gene

Subcategory (RNA class) for MIR148A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR148A Gene

  • MicroRNA 148a 2 3
  • MicroRNA 148 2 3
  • MIRN148A 3 6
  • Hsa-Mir-148a 3
  • Hsa-Mir-148 3
  • MIRN148 3

External Ids for MIR148A Gene

ORGUL Members for MIR148A Gene

Previous HGNC Symbols for MIR148A Gene

  • MIRN148
  • MIRN148A

Previous GeneCards Identifiers for MIR148A Gene

  • GC07M025957
  • GC07M025990

Summaries for MIR148A Gene

Entrez Gene Summary for MIR148A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR148A Gene

MIR148A (MicroRNA 148a) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR148A Gene

Genomics for MIR148A Gene

Genomic Location for MIR148A Gene

Start:
25,949,903 bp from pter
End:
25,950,013 bp from pter
Size:
111 bases
Orientation:
Minus strand

Genomic View for MIR148A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR148A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR148A Gene

No data available for Regulatory Elements for MIR148A Gene

Proteins for MIR148A Gene

Post-translational modifications for MIR148A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR148A Gene

Domains for MIR148A Gene

Gene Families for MIR148A Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR148A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR148A Gene

Function for MIR148A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR148A Gene

Localization for MIR148A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR148A Gene

Pathways for MIR148A Gene

SuperPathways for MIR148A Gene

No Data Available

Interacting Proteins for MIR148A Gene

Gene Ontology (GO) - Biological Process for MIR148A Gene

None

No data available for Pathways by source for MIR148A Gene

Transcripts for MIR148A Gene

mRNA/cDNA for MIR148A Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR148A Gene

No ASD Table

Relevant External Links for MIR148A Gene

GeneLoc Exon Structure for
MIR148A
ECgene alternative splicing isoforms for
MIR148A

Expression for MIR148A Gene

genes like me logo Genes that share expressions with MIR148A: view

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR148A Gene

Orthologs for MIR148A Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR148A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-148a 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-148a 36
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-148a 36
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir148a 36
  • 66 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-148 36
  • 74 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-148a 36
  • 88 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-148a 36
  • 63 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii BX546447.1 36
  • 67 (a)
ManyToMany
Species with no ortholog for MIR148A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR148A Gene

ENSEMBL:
Gene Tree for MIR148A (if available)
TreeFam:
Gene Tree for MIR148A (if available)

Paralogs for MIR148A Gene

No data available for Paralogs for MIR148A Gene

Variants for MIR148A Gene

Sequence variations from dbSNP and Humsavar for MIR148A Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs2893233 -- 25,950,933(+) GTGGG(C/T)TGCGT upstream-variant-2KB
rs4000712 -- 25,950,869(+) CCCCC(-/CA)AAACC upstream-variant-2KB
rs4000713 -- 25,950,977(+) GTGCG(A/G)GGCGC upstream-variant-2KB
rs6953596 -- 25,949,678(+) TCTTT(A/C)AACCA downstream-variant-500B
rs6977848 -- 25,949,900(+) CGGCA(G/T)CGGCG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR148A Gene

Variant ID Type Subtype PubMed ID
nsv7393 OTHER Inversion 18451855

Relevant External Links for MIR148A Gene

HapMap Linkage Disequilibrium report
MIR148A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR148A Gene

Disorders for MIR148A Gene

No disorders were found for MIR148A Gene.

No data available for UniProtKB/Swiss-Prot for MIR148A Gene

Publications for MIR148A Gene

  1. Identification of tissue-specific microRNAs from mouse. (PMID: 12007417) Lagos-Quintana M. … Tuschl T. (Curr. Biol. 2002) 3
  2. Identification of human fetal liver miRNAs by a novel method. (PMID: 15978578) Fu H. … Zheng X. (FEBS Lett. 2005) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  5. MiR-148a attenuates paclitaxel resistance of hormone-refractory, drug-resistant prostate cancer PC3 cells by regulating MSK1 expression. (PMID: 20406806) Fujita Y. … Ito M. (J. Biol. Chem. 2010) 3

Products for MIR148A Gene

Sources for MIR148A Gene

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