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Aliases for MIR147B Gene

Subcategory (RNA class) for MIR147B Gene

undefined

Quality Score for this RNA gene is

3

Aliases for MIR147B Gene

  • MicroRNA 147b 2 3 5
  • Hsa-Mir-147b 3
  • Mir-147b 3
  • MIRN147B 3

External Ids for MIR147B Gene

ORGUL Members for MIR147B Gene

Previous HGNC Symbols for MIR147B Gene

  • MIRN147B

Previous GeneCards Identifiers for MIR147B Gene

  • GC15P043514
  • GC15P045725

Summaries for MIR147B Gene

Entrez Gene Summary for MIR147B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR147B Gene

MIR147B (MicroRNA 147b) is an RNA Gene, and is affiliated with the undefined RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR147B Gene

Genomics for MIR147B Gene

Regulatory Elements for MIR147B Gene

Promoters for MIR147B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MIR147B on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR147B Gene

Chromosome:
15
Start:
45,433,050 bp from pter
End:
45,433,129 bp from pter
Size:
80 bases
Orientation:
Plus strand

Genomic View for MIR147B Gene

Genes around MIR147B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR147B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR147B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR147B Gene

Proteins for MIR147B Gene

Post-translational modifications for MIR147B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR147B Gene

Domains & Families for MIR147B Gene

Gene Families for MIR147B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR147B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR147B Gene

Function for MIR147B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR147B Gene

Localization for MIR147B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR147B Gene

Pathways & Interactions for MIR147B Gene

SuperPathways for MIR147B Gene

No Data Available

Interacting Proteins for MIR147B Gene

Gene Ontology (GO) - Biological Process for MIR147B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR147B Gene

Drugs & Compounds for MIR147B Gene

No Compound Related Data Available

Transcripts for MIR147B Gene

mRNA/cDNA for MIR147B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR147B Gene

No ASD Table

Relevant External Links for MIR147B Gene

GeneLoc Exon Structure for
MIR147B
ECgene alternative splicing isoforms for
MIR147B

Expression for MIR147B Gene

mRNA expression in normal human tissues for MIR147B Gene

mRNA differential expression in normal tissues according to GTEx for MIR147B Gene

This gene is overexpressed in Colon - Transverse (x25.2), Esophagus - Mucosa (x5.4), and Small Intestine - Terminal Ileum (x5.0).
genes like me logo Genes that share expression patterns with MIR147B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR147B Gene

Orthologs for MIR147B Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR147B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-147b 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-147 36
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 36
  • 87 (a)
OneToMany
cfa-mir-147 36
  • 88 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Mir147 36
  • 92 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 83 (a)
ManyToMany
-- 36
  • 82 (a)
ManyToMany
mdo-mir-147b 36
  • 87 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-147 36
  • 54 (a)
OneToMany
chicken
(Gallus gallus)
Aves gga-mir-147 36
  • 87 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia aca-mir-147 36
  • 84 (a)
OneToMany
Species with no ortholog for MIR147B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR147B Gene

ENSEMBL:
Gene Tree for MIR147B (if available)
TreeFam:
Gene Tree for MIR147B (if available)

Paralogs for MIR147B Gene

No data available for Paralogs for MIR147B Gene

Variants for MIR147B Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR147B Gene

Variant ID Type Subtype PubMed ID
nsv469721 CNV Complex 16826518

Relevant External Links for MIR147B Gene

HapMap Linkage Disequilibrium report
MIR147B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR147B Gene

Disorders for MIR147B Gene

Relevant External Links for MIR147B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR147B

No disorders were found for MIR147B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR147B Gene

Publications for MIR147B Gene

  1. MicroRNAs 146a and 147b biomarkers for colorectal tumor's localization. (PMID: 24800242) Omrane I. … Benammar-Elgaaied A. (Biomed Res Int 2014) 3
  2. "Seed-Milarity" confers to hsa-miR-210 and hsa-miR-147b similar functional activity. (PMID: 23028679) Bertero T. … Mari B. (PLoS ONE 2012) 3
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR147B Gene

Sources for MIR147B Gene

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