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Aliases for MIR147A Gene

Subcategory (RNA class) for MIR147A Gene


Quality Score for this RNA gene is


Aliases for MIR147A Gene

  • MicroRNA 147a 2 3 5
  • MicroRNA 147 2 3
  • Hsa-Mir-147a 3
  • Hsa-Mir-147 3
  • MIRN147 3
  • MIR147 3

External Ids for MIR147A Gene

Previous HGNC Symbols for MIR147A Gene

  • MIRN147
  • MIR147

Previous GeneCards Identifiers for MIR147A Gene

  • GC09M123008
  • GC09M123010
  • GC09M123013

Summaries for MIR147A Gene

Entrez Gene Summary for MIR147A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR147A Gene

MIR147A (MicroRNA 147a) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR147A Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR147A

Additional gene information for MIR147A Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR147A Gene

Genomics for MIR147A Gene

GeneHancer (GH) Regulatory Elements for MIR147A Gene

Promoters and enhancers for MIR147A Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09I120264 Enhancer 0.4 ENCODE 12.2 -20.5 -20496 1.5 ZNF366 SCRT2 MIR147A LOC105376253
GH09I120091 Enhancer 0.2 FANTOM5 10.3 +153.8 153824 0 MIR147A GC09P120186 ENSG00000225960
GH09I120383 Enhancer 1.3 Ensembl ENCODE dbSUPER 0.1 -139.3 -139317 1.6 FOXA2 MLX ARID4B DMAP1 ZNF48 ETS1 YY1 RXRA ZHX2 MIER2 LOC105376253 MIR147A
GH09I120365 Enhancer 0.9 Ensembl ENCODE 0.1 -121.6 -121631 1.5 ELF3 CTCF ARID4B CEBPG RAD21 ETS1 TEAD3 GATA3 SMC3 RCOR1 LOC105376253 MIR147A
GH09I120325 Enhancer 0.4 ENCODE 0.2 -80.2 -80168 0.2 CTCF NR2F1 ZNF143 LOC105376253 MIR147A
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR147A on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR147A Gene

Genomic Locations for MIR147A Gene
72 bases
Minus strand

Genomic View for MIR147A Gene

Genes around MIR147A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR147A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR147A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR147A Gene

ORGUL Member Location for MIR147A Gene

ORGUL Member Location for MIR147A gene

Proteins for MIR147A Gene

Post-translational modifications for MIR147A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR147A Gene

Domains & Families for MIR147A Gene

Gene Families for MIR147A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR147A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR147A Gene

Function for MIR147A Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR147A Gene

Localization for MIR147A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR147A Gene

Pathways & Interactions for MIR147A Gene

SuperPathways for MIR147A Gene

No Data Available

Interacting Proteins for MIR147A Gene

Gene Ontology (GO) - Biological Process for MIR147A Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR147A Gene

Drugs & Compounds for MIR147A Gene

No Compound Related Data Available

Transcripts for MIR147A Gene

fRNAdb Secondary structures for MIR147A Gene

  • hsa-miR-147a_MIMAT0000251_Homo_sapiens_miR-147a_mature

mRNA/cDNA for MIR147A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR147A Gene

No ASD Table

Relevant External Links for MIR147A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR147A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR147A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR147A Gene:

genes like me logo Genes that share expression patterns with MIR147A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR147A Gene

Orthologs for MIR147A Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR147A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-147a 34
  • 99 (a)
(Bos Taurus)
Mammalia -- 34
  • 78 (a)
(Monodelphis domestica)
Mammalia mdo-mir-147b 34
  • 68 (a)
-- 34
  • 66 (a)
-- 34
  • 66 (a)
(Canis familiaris)
Mammalia -- 34
  • 65 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-147 34
  • 43 (a)
(Gallus gallus)
Aves gga-mir-147 34
  • 79 (a)
(Anolis carolinensis)
Reptilia aca-mir-147 34
  • 64 (a)
Species where no ortholog for MIR147A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR147A Gene

Gene Tree for MIR147A (if available)
Gene Tree for MIR147A (if available)

Paralogs for MIR147A Gene

No data available for Paralogs for MIR147A Gene

Variants for MIR147A Gene

Sequence variations from dbSNP and Humsavar for MIR147A Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000143511 -- 120,245,513(-) A/G upstream_transcript_variant
rs1000241671 -- 120,246,880(-) T/C upstream_transcript_variant
rs1000706826 -- 120,246,956(-) A/G upstream_transcript_variant
rs1001097883 -- 120,246,545(-) A/G upstream_transcript_variant
rs1004609088 -- 120,246,131(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR147A Gene

Variant ID Type Subtype PubMed ID
nsv1048345 CNV loss 25217958
nsv7434 OTHER inversion 18451855

Additional Variant Information for MIR147A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR147A Gene

Disorders for MIR147A Gene

Additional Disease Information for MIR147A

No disorders were found for MIR147A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR147A Gene

Publications for MIR147A Gene

  1. Identification of tissue-specific microRNAs from mouse. (PMID: 12007417) Lagos-Quintana M … Tuschl T (Current biology : CB 2002) 1 3 58
  2. A novel hypoxia-induced miR-147a regulates cell proliferation through a positive feedback loop of stabilizing HIF-1α. (PMID: 27260617) Wang F … Zhang Y (Cancer biology & therapy 2016) 3 58
  3. Genome-wide association studies and heritability estimates of body mass index related phenotypes in Bangladeshi adults. (PMID: 25133637) Scannell Bryan M … Ahsan H (PloS one 2014) 3 58
  4. Global microRNA level regulation of EGFR-driven cell-cycle protein network in breast cancer. (PMID: 22333974) Uhlmann S … Sahin O (Molecular systems biology 2012) 3 58
  5. Genome-wide association of lipid-lowering response to statins in combined study populations. (PMID: 20339536) Barber MJ … Krauss RM (PloS one 2010) 3 58

Products for MIR147A Gene

Sources for MIR147A Gene

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