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Aliases for MIR1468 Gene

Subcategory (RNA class) for MIR1468 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1468 Gene

  • MicroRNA 1468 2 3
  • Hsa-Mir-1468 3
  • MIRN1468 3

External Ids for MIR1468 Gene

Previous HGNC Symbols for MIR1468 Gene

  • MIRN1468

Previous GeneCards Identifiers for MIR1468 Gene

  • GC00U922875
  • GC0XM062923

Summaries for MIR1468 Gene

Entrez Gene Summary for MIR1468 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1468 Gene

MIR1468 (MicroRNA 1468) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR1468 include systemic lupus erythematosus.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1468 Gene

Genomics for MIR1468 Gene

Genomic Location for MIR1468 Gene

Start:
63,786,002 bp from pter
End:
63,786,087 bp from pter
Size:
86 bases
Orientation:
Minus strand

Genomic View for MIR1468 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR1468 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1468 Gene

No data available for Regulatory Elements for MIR1468 Gene

Proteins for MIR1468 Gene

Post-translational modifications for MIR1468 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1468 Gene

Domains for MIR1468 Gene

Gene Families for MIR1468 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1468: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1468 Gene

Function for MIR1468 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR1468 Gene

Localization for MIR1468 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1468 Gene

Pathways for MIR1468 Gene

SuperPathways for MIR1468 Gene

No Data Available

Interacting Proteins for MIR1468 Gene

Gene Ontology (GO) - Biological Process for MIR1468 Gene

None

No data available for Pathways by source for MIR1468 Gene

Transcripts for MIR1468 Gene

mRNA/cDNA for MIR1468 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1468 Gene

No ASD Table

Relevant External Links for MIR1468 Gene

GeneLoc Exon Structure for
MIR1468
ECgene alternative splicing isoforms for
MIR1468

Expression for MIR1468 Gene

mRNA expression in normal human tissues for MIR1468 Gene

genes like me logo Genes that share expressions with MIR1468: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR1468 Gene

Orthologs for MIR1468 Gene

Evolution for MIR1468 Gene

ENSEMBL:
Gene Tree for MIR1468 (if available)
TreeFam:
Gene Tree for MIR1468 (if available)

No data available for Orthologs for MIR1468 Gene

Paralogs for MIR1468 Gene

No data available for Paralogs for MIR1468 Gene

Variants for MIR1468 Gene

Sequence variations from dbSNP and Humsavar for MIR1468 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs35686782 -- 63,787,782(+) ATGGG(-/G)TTGGA upstream-variant-2KB
rs73526867 -- 63,787,949(+) CATGT(C/T)TCCCA upstream-variant-2KB
rs142814797 -- 63,787,582(+) GTGCC(A/G)GTCAT upstream-variant-2KB
rs147401170 -- 63,787,819(+) ATGGA(A/G)GAGTT upstream-variant-2KB
rs183504233 -- 63,787,580(+) CTGTG(C/T)CGGTC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1468 Gene

Variant ID Type Subtype PubMed ID
esv1584074 OTHER Inversion 17803354

Relevant External Links for MIR1468 Gene

HapMap Linkage Disequilibrium report
MIR1468

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR1468 Gene

Disorders for MIR1468 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for MIR1468 Gene including...

Search for MIR1468 Gene in MalaCards »

Relevant External Links for MIR1468

Human Genome Epidemiology (HuGE) Navigator
MIR1468
genes like me logo Genes that share disorders with MIR1468: view

No data available for UniProtKB/Swiss-Prot for MIR1468 Gene

Publications for MIR1468 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. (PMID: 16954537) Berezikov E. … Cuppen E. (Genome Res. 2006) 3
  3. Hidden layers of human small RNAs. (PMID: 18402656) Kawaji H. … Hayashizaki Y. (BMC Genomics 2008) 3
  4. The association between two polymorphisms in pre-miRNAs and breast cancer risk: a meta-analysis. (PMID: 20640596) Gao L.B. … Zhang L. (Breast Cancer Res. Treat. 2011) 3
  5. Association of pre-microRNAs genetic variants with susceptibility in systemic lupus erythematosus. (PMID: 20845080) Zhang J. … Wang L. (Mol. Biol. Rep. 2011) 3

Products for MIR1468 Gene

Sources for MIR1468 Gene

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