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Aliases for MIR145 Gene

Subcategory (RNA class) for MIR145 Gene


Quality Score for this RNA gene is


Aliases for MIR145 Gene

  • MicroRNA 145 2 3 5
  • Hsa-Mir-145 3
  • MiRNA145 3
  • MiR-145 3
  • MIRN145 3

External Ids for MIR145 Gene

ORGUL Members for MIR145 Gene

Previous HGNC Symbols for MIR145 Gene

  • MIRN145

Previous GeneCards Identifiers for MIR145 Gene

  • GC05P148794
  • GC05P148810

Summaries for MIR145 Gene

Entrez Gene Summary for MIR145 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR145 Gene

MIR145 (MicroRNA 145) is an RNA Gene, and is affiliated with the undefined RNA class. Among its related pathways are SRF and miRs in Smooth Muscle Differentiation and Proliferation and miRNAs involved in DDR.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR145 Gene

Genomics for MIR145 Gene

Regulatory Elements for MIR145 Gene

Enhancers for MIR145 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR145 on UCSC Golden Path with GeneCards custom track

Promoters for MIR145 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MIR145 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR145 Gene

149,430,646 bp from pter
149,430,733 bp from pter
88 bases
Plus strand

Genomic View for MIR145 Gene

Genes around MIR145 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR145 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR145 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR145 Gene

Proteins for MIR145 Gene

Post-translational modifications for MIR145 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR145 Gene

Domains & Families for MIR145 Gene

Gene Families for MIR145 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR145: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR145 Gene

Function for MIR145 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR145 Gene

Localization for MIR145 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR145 Gene

Pathways & Interactions for MIR145 Gene

genes like me logo Genes that share pathways with MIR145: view

Pathways by source for MIR145 Gene

Interacting Proteins for MIR145 Gene

Gene Ontology (GO) - Biological Process for MIR145 Gene


No data available for SIGNOR curated interactions for MIR145 Gene

Drugs & Compounds for MIR145 Gene

No Compound Related Data Available

Transcripts for MIR145 Gene

mRNA/cDNA for MIR145 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR145 Gene

No ASD Table

Relevant External Links for MIR145 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR145 Gene

mRNA expression in normal human tissues for MIR145 Gene

mRNA differential expression in normal tissues according to GTEx for MIR145 Gene

This gene is overexpressed in Esophagus - Gastroesophageal Junction (x7.0), Colon - Sigmoid (x6.8), and Esophagus - Muscularis (x5.9).
genes like me logo Genes that share expression patterns with MIR145: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR145 Gene

Orthologs for MIR145 Gene

Evolution for MIR145 Gene

Gene Tree for MIR145 (if available)
Gene Tree for MIR145 (if available)

No data available for Orthologs for MIR145 Gene

Paralogs for MIR145 Gene

No data available for Paralogs for MIR145 Gene

Variants for MIR145 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for MIR145 Gene

Disorders for MIR145 Gene

Relevant External Links for MIR145

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR145 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR145 Gene

Publications for MIR145 Gene

  1. miR-21 and miR-145 cooperation in regulation of colon cancer stem cells. (PMID: 25928322) Yu Y. … Majumdar A.P. (Mol. Cancer 2015) 3 67
  2. Altered microRNA expression in inflamed and non-inflamed terminal ileal mucosa of adult patients with active Crohn's disease. (PMID: 24910152) Guo Z. … Li J. (J. Gastroenterol. Hepatol. 2015) 3
  3. The epigenetic regulation of SOX9 by miR-145 in human chondrosarcoma. (PMID: 25145279) Mak I.W. … Ghert M. (J. Cell. Biochem. 2015) 3
  4. Transcription factors and miRNAs that regulate fetal to adult CFTR expression change are new targets for cystic fibrosis. (PMID: 25186262) Viart V. … Taulan-Cadars M. (Eur. Respir. J. 2015) 3
  5. lincRNA-RoR and miR-145 regulate invasion in triple-negative breast cancer via targeting ARF6. (PMID: 25253741) Eades G. … Zhou Q. (Mol. Cancer Res. 2015) 3

Products for MIR145 Gene

Sources for MIR145 Gene