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Aliases for MIR145 Gene

Subcategory (RNA class) for MIR145 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR145 Gene

  • MicroRNA 145 2 3
  • MIRN145 3 6
  • Hsa-Mir-145 3
  • MiRNA145 3
  • MiR-145 3

External Ids for MIR145 Gene

Previous HGNC Symbols for MIR145 Gene

  • MIRN145

Previous GeneCards Identifiers for MIR145 Gene

  • GC05P148794
  • GC05P148810

Summaries for MIR145 Gene

Entrez Gene Summary for MIR145 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR145 Gene

MIR145 (MicroRNA 145) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR145 include endometrial adenocarcinoma and ewing sarcoma. Among its related pathways are Heart Development and MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR145 Gene

Genomics for MIR145 Gene

Genomic Location for MIR145 Gene

Start:
149,430,646 bp from pter
End:
149,430,733 bp from pter
Size:
88 bases
Orientation:
Plus strand

Genomic View for MIR145 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR145 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR145 Gene

No data available for Regulatory Elements for MIR145 Gene

Proteins for MIR145 Gene

Post-translational modifications for MIR145 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR145 Gene

Domains for MIR145 Gene

Gene Families for MIR145 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR145: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR145 Gene

Function for MIR145 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR145 Gene

Localization for MIR145 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR145 Gene

Pathways for MIR145 Gene

genes like me logo Genes that share pathways with MIR145: view

Pathways by source for MIR145 Gene

Interacting Proteins for MIR145 Gene

Gene Ontology (GO) - Biological Process for MIR145 Gene

None

Transcripts for MIR145 Gene

mRNA/cDNA for MIR145 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR145 Gene

No ASD Table

Relevant External Links for MIR145 Gene

GeneLoc Exon Structure for
MIR145
ECgene alternative splicing isoforms for
MIR145

Expression for MIR145 Gene

mRNA expression in normal human tissues for MIR145 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MIR145 Gene

This gene is overexpressed in Esophagus - Gastroesophageal Junction (7.0), Colon - Sigmoid (6.8), and Esophagus - Muscularis (5.9).
genes like me logo Genes that share expressions with MIR145: view

In Situ Assay Products

No data available for Protein expression and mRNA Expression by UniProt/SwissProt for MIR145 Gene

Orthologs for MIR145 Gene

Evolution for MIR145 Gene

ENSEMBL:
Gene Tree for MIR145 (if available)
TreeFam:
Gene Tree for MIR145 (if available)

No data available for Orthologs for MIR145 Gene

Paralogs for MIR145 Gene

No data available for Paralogs for MIR145 Gene

Variants for MIR145 Gene

Relevant External Links for MIR145 Gene

HapMap Linkage Disequilibrium report
MIR145

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR145 Gene

Disorders for MIR145 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (2) Diseases for MIR145 Gene including...

Search for MIR145 Gene in MalaCards »

Relevant External Links for MIR145

Genetic Association Database (GAD)
MIR145
Human Genome Epidemiology (HuGE) Navigator
MIR145
genes like me logo Genes that share disorders with MIR145: view

No data available for UniProtKB/Swiss-Prot for MIR145 Gene

Publications for MIR145 Gene

  1. Identification of tissue-specific microRNAs from mouse. (PMID: 12007417) Lagos-Quintana M. … Tuschl T. (Curr. Biol. 2002) 3
  2. Reduced accumulation of specific microRNAs in colorectal neoplasia. (PMID: 14573789) Michael M.Z. … James R.J. (Mol. Cancer Res. 2003) 3
  3. Identification of human fetal liver miRNAs by a novel method. (PMID: 15978578) Fu H. … Zheng X. (FEBS Lett. 2005) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  5. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3

Products for MIR145 Gene

Sources for MIR145 Gene

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