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Aliases for MIR143 Gene

Subcategory (RNA class) for MIR143 Gene


Quality Score for this RNA gene is


Aliases for MIR143 Gene

  • MicroRNA 143 2 3
  • MIRN143 3 6
  • Hsa-Mir-143 3

External Ids for MIR143 Gene

ORGUL Members for MIR143 Gene

Previous HGNC Symbols for MIR143 Gene

  • MIRN143

Previous GeneCards Identifiers for MIR143 Gene

  • GC05P148793
  • GC05P148808

Summaries for MIR143 Gene

Entrez Gene Summary for MIR143 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR143 Gene

MIR143 (MicroRNA 143) is an RNA Gene, and is affiliated with the undefined RNA class. Among its related pathways are Heart Development and MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR143 Gene

Genomics for MIR143 Gene

Genomic Location for MIR143 Gene

149,428,918 bp from pter
149,429,023 bp from pter
106 bases
Plus strand

Genomic View for MIR143 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR143 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR143 Gene

No data available for Regulatory Elements for MIR143 Gene

Proteins for MIR143 Gene

Post-translational modifications for MIR143 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR143 Gene

Domains for MIR143 Gene

Gene Families for MIR143 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR143: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR143 Gene

Function for MIR143 Gene

miRNA for MIR143 Gene

miRTarBase miRNAs that target MIR143

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for MIR143 Gene

Localization for MIR143 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR143 Gene

Pathways for MIR143 Gene

genes like me logo Genes that share pathways with MIR143: view

Pathways by source for MIR143 Gene

Interacting Proteins for MIR143 Gene

Gene Ontology (GO) - Biological Process for MIR143 Gene


Transcripts for MIR143 Gene

mRNA/cDNA for MIR143 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR143 Gene

No ASD Table

Relevant External Links for MIR143 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR143 Gene

mRNA expression in normal human tissues for MIR143 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MIR143 Gene

This gene is overexpressed in Esophagus - Gastroesophageal Junction (11.0), Esophagus - Muscularis (8.3), and Artery - Coronary (5.3).
genes like me logo Genes that share expressions with MIR143: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR143 Gene

Orthologs for MIR143 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR143 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-143 36
  • 97 (a)
(Canis familiaris)
Mammalia cfa-mir-143 36
  • 100 (a)
(Monodelphis domestica)
Mammalia mdo-mir-143 36
  • 95 (a)
(Mus musculus)
Mammalia Mir143 36
  • 98 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-143 36
  • 90 (a)
(Pan troglodytes)
Mammalia ptr-mir-143 36
  • 99 (a)
(Gallus gallus)
Aves -- 36
  • 89 (a)
(Anolis carolinensis)
Reptilia aca-mir-143 36
  • 91 (a)
(Danio rerio)
Actinopterygii dre-mir-143-2 36
  • 74 (a)
dre-mir-143-2 36
  • 74 (a)
Species with no ortholog for MIR143:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR143 Gene

Gene Tree for MIR143 (if available)
Gene Tree for MIR143 (if available)

Paralogs for MIR143 Gene

No data available for Paralogs for MIR143 Gene

Variants for MIR143 Gene

Relevant External Links for MIR143 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR143 Gene

Disorders for MIR143 Gene

Relevant External Links for MIR143

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for MIR143 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for MIR143 Gene

Publications for MIR143 Gene

  1. Novel genetic variants in miR-191 gene and familial ovarian cancer. (PMID: 20167074) Shen J. … Zhao H. (BMC Cancer 2010) 3 48
  2. Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis. (PMID: 20363096) Gao W. … Shu Y. (Biomed. Pharmacother. 2010) 3
  3. Identification of non-coding RNAs embracing microRNA-143/145 cluster. (PMID: 20525177) Iio A. … Akao Y. (Mol. Cancer 2010) 3
  4. Relevance of miR-21 and miR-143 expression in tissue samples of colorectal carcinoma and its liver metastases. (PMID: 20620599) Kulda V. … Cerny R. (Cancer Genet. Cytogenet. 2010) 3
  5. Expression patterns of microRNAs are altered in hypoxic human neuroblastoma cells. (PMID: 20809117) Yamagata T. … Ohki T. (Pediatr. Surg. Int. 2010) 3

Products for MIR143 Gene

Sources for MIR143 Gene

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