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Aliases for MIR142 Gene

Subcategory (RNA class) for MIR142 Gene

lncRNA

Quality Score for this RNA gene is

3.2

Aliases for MIR142 Gene

  • MicroRNA 142 2 3 5
  • Hsa-Mir-142 3
  • Mir-142 3
  • MIRN142 3

External Ids for MIR142 Gene

ORGUL Members for MIR142 Gene

Previous HGNC Symbols for MIR142 Gene

  • MIRN142

Previous GeneCards Identifiers for MIR142 Gene

  • GC17M053766
  • GC17M056409

Summaries for MIR142 Gene

Entrez Gene Summary for MIR142 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR142 Gene

MIR142 (MicroRNA 142) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with MIR142 include Bladder Carcinoma In Situ.

fRNAdb sequence ontologies for MIR142 Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR142

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR142 Gene

Genomics for MIR142 Gene

Regulatory Elements for MIR142 Gene


Promoters for MIR142 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MIR142 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR142 Gene

Chromosome:
17
Start:
58,330,884 bp from pter
End:
58,332,508 bp from pter
Size:
1,625 bases
Orientation:
Minus strand

Genomic View for MIR142 Gene

Genes around MIR142 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR142 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR142 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR142 Gene

Proteins for MIR142 Gene

Post-translational modifications for MIR142 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR142 Gene

Domains & Families for MIR142 Gene

Gene Families for MIR142 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR142: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR142 Gene

Function for MIR142 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR142 Gene

Localization for MIR142 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR142 Gene

Pathways & Interactions for MIR142 Gene

SuperPathways for MIR142 Gene

No Data Available

Interacting Proteins for MIR142 Gene

Gene Ontology (GO) - Biological Process for MIR142 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR142 Gene

Drugs & Compounds for MIR142 Gene

No Compound Related Data Available

Transcripts for MIR142 Gene

fRNAdb Secondary structures for MIR142 Gene

  • FR111987

mRNA/cDNA for MIR142 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR142 Gene

No ASD Table

Relevant External Links for MIR142 Gene

GeneLoc Exon Structure for
MIR142
ECgene alternative splicing isoforms for
MIR142

Expression for MIR142 Gene

mRNA expression in normal human tissues for MIR142 Gene

mRNA differential expression in normal tissues according to GTEx for MIR142 Gene

This gene is overexpressed in Whole Blood (x17.7) and Spleen (x9.2).

NURSA nuclear receptor signaling pathways regulating expression of MIR142 Gene:

MIR142
genes like me logo Genes that share expression patterns with MIR142: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR142 Gene

Orthologs for MIR142 Gene

Evolution for MIR142 Gene

ENSEMBL:
Gene Tree for MIR142 (if available)
TreeFam:
Gene Tree for MIR142 (if available)

No data available for Orthologs for MIR142 Gene

Paralogs for MIR142 Gene

No data available for Paralogs for MIR142 Gene

Variants for MIR142 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR142 Gene

Variant ID Type Subtype PubMed ID
nsv457860 CNV loss 19166990
nsv509663 CNV insertion 20534489
nsv517229 CNV gain+loss 19592680
nsv575799 CNV loss 21841781

Relevant External Links for MIR142 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR142

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR142 Gene

Disorders for MIR142 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR142 Gene - From: GeneCards

Disorder Aliases PubMed IDs
bladder carcinoma in situ
  • bladder ca in situ
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR142

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR142
genes like me logo Genes that share disorders with MIR142: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR142 Gene

Publications for MIR142 Gene

  1. miR-142-3p inhibits cancer cell proliferation by targeting CDC25C. (PMID: 26805039) Cao X.C. … Wang X. (Cell Prolif. 2016) 3 65
  2. RBM3 regulates temperature sensitive miR-142-5p and miR-143 (thermomiRs), which target immune genes and control fever. (PMID: 26825461) Wong J.J. … Ritchie W. (Nucleic Acids Res. 2016) 3 65
  3. miR-142-3p down-regulation contributes to thyroid follicular tumorigenesis by targeting ASH1L and MLL1. (PMID: 25238203) Colamaio M. … Fusco A. (J. Clin. Endocrinol. Metab. 2015) 3 65
  4. MiR-142 acts as a tumor suppressor in osteosarcoma cell lines by targeting Rac1. (PMID: 25530132) Zheng Z. … Wang J. (Oncol. Rep. 2015) 3 65
  5. Upregulation of miR-142-5p in atherosclerotic plaques and regulation of oxidized low-density lipoprotein-induced apoptosis in macrophages. (PMID: 25586666) Xu R. … Zhang M. (Mol Med Rep 2015) 3 65

Products for MIR142 Gene

Sources for MIR142 Gene

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