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Aliases for MIR142 Gene

Subcategory (RNA class) for MIR142 Gene

lncRNA

Quality Score for this RNA gene is

3.2

Aliases for MIR142 Gene

  • MicroRNA 142 2 3
  • Hsa-Mir-142 3
  • MIRN142 3

External Ids for MIR142 Gene

ORGUL Members for MIR142 Gene

Previous Symbols for MIR142 Gene

  • MIRN142

Summaries for MIR142 Gene

Entrez Gene Summary for MIR142 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR142 Gene

MIR142 (MicroRNA 142) is an RNA Gene, and belongs to the lncRNA class. Diseases associated with MIR142 include bladder carcinoma in situ.

fRNAdb sequence ontologies for MIR142 Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR142

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR142 Gene

Genomics for MIR142 Gene

Genomic Location for MIR142 Gene

Start:
58,331,215 bp from pter
End:
58,331,325 bp from pter
Size:
111 bases
Orientation:
Minus strand

Genomic View for MIR142 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR142 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR142 Gene

ORGUL Member Location for MIR142 Gene

ORGUL Member Location for MIR142 gene

No data available for Regulatory Elements for MIR142 Gene

Proteins for MIR142 Gene

Post-translational modifications for MIR142 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR142 Gene

Domains for MIR142 Gene

Gene Families for MIR142 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR142: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR142 Gene

Function for MIR142 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR142 Gene

Localization for MIR142 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR142 Gene

Pathways for MIR142 Gene

SuperPathways for MIR142 Gene

No Data Available

Interacting Proteins for MIR142 Gene

Gene Ontology (GO) - Biological Process for MIR142 Gene

None

No data available for Pathways by source for MIR142 Gene

Transcripts for MIR142 Gene

fRNAdb Secondary structures for MIR142 Gene

  • FR111987

mRNA/cDNA for MIR142 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR142 Gene

No ASD Table

Relevant External Links for MIR142 Gene

GeneLoc Exon Structure for
MIR142
ECgene alternative splicing isoforms for
MIR142

Expression for MIR142 Gene

mRNA expression in normal human tissues for MIR142 Gene

mRNA differential expression in normal tissues according to GTEx for MIR142 Gene

This gene is overexpressed in Whole Blood (17.7) and Spleen (9.2).
genes like me logo Genes that share expressions with MIR142: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for MIR142 Gene

Orthologs for MIR142 Gene

Evolution for MIR142 Gene

ENSEMBL:
Gene Tree for MIR142 (if available)
TreeFam:
Gene Tree for MIR142 (if available)

No data available for Orthologs for MIR142 Gene

Paralogs for MIR142 Gene

No data available for Paralogs for MIR142 Gene

Variants for MIR142 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR142 Gene

Variant ID Type Subtype PubMed ID
nsv517229 CNV Gain+Loss 19592680
nsv509663 CNV Insertion 20534489
dgv3235n71 CNV Loss 21882294
nsv457860 CNV Loss 19166990

Relevant External Links for MIR142 Gene

HapMap Linkage Disequilibrium report
MIR142

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR142 Gene

Disorders for MIR142 Gene

(1) MalaCards Diseases for MIR142 Gene

Search for MIR142 Gene in MalaCards »
genes like me logo Genes that share disorders with MIR142: view

No data available for UniProtKB/Swiss-Prot for MIR142 Gene

Publications for MIR142 Gene

  1. Identification of tissue-specific microRNAs from mouse. (PMID: 12007417) Lagos-Quintana M. … Tuschl T. (Curr. Biol. 2002) 3
  2. Reduced accumulation of specific microRNAs in colorectal neoplasia. (PMID: 14573789) Michael M.Z. … James R.J. (Mol. Cancer Res. 2003) 3
  3. Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells. (PMID: 15325244) Kasashima K. … Kozu T. (Biochem. Biophys. Res. Commun. 2004) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  5. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3

Products for MIR142 Gene

Sources for MIR142 Gene

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