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Aliases for MIR136 Gene

Subcategory (RNA class) for MIR136 Gene


Quality Score for this RNA gene is


Aliases for MIR136 Gene

  • MicroRNA 136 2 3
  • Hsa-Mir-136 3
  • MiRNA136 3
  • Mir-136 3
  • MIRN136 3

External Ids for MIR136 Gene

ORGUL Members for MIR136 Gene

Previous HGNC Symbols for MIR136 Gene

  • MIRN136

Previous GeneCards Identifiers for MIR136 Gene

  • GC14P100495
  • GC14P100865
  • GC14P101351
  • GC14P101081

Summaries for MIR136 Gene

Entrez Gene Summary for MIR136 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR136 Gene

MIR136 (MicroRNA 136) is an RNA Gene, and is affiliated with the undefined RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR136 Gene

Genomics for MIR136 Gene

Genomic Location for MIR136 Gene

100,884,697 bp from pter
100,884,788 bp from pter
92 bases
Plus strand

Genomic View for MIR136 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR136 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR136 Gene

No data available for Regulatory Elements for MIR136 Gene

Proteins for MIR136 Gene

Post-translational modifications for MIR136 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR136 Gene

Domains & Families for MIR136 Gene

Gene Families for MIR136 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR136: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR136 Gene

Function for MIR136 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR136 Gene

Localization for MIR136 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR136 Gene

Pathways & Interactions for MIR136 Gene

SuperPathways for MIR136 Gene

No Data Available

Interacting Proteins for MIR136 Gene

Gene Ontology (GO) - Biological Process for MIR136 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR136 Gene

Drugs & Compounds for MIR136 Gene

No Compound Related Data Available

Transcripts for MIR136 Gene

mRNA/cDNA for MIR136 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR136 Gene

No ASD Table

Relevant External Links for MIR136 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR136 Gene

mRNA expression in normal human tissues for MIR136 Gene

genes like me logo Genes that share expression patterns with MIR136: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR136 Gene

Orthologs for MIR136 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR136 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-136 36
  • 98 (a)
(Canis familiaris)
Mammalia cfa-mir-136 36
  • 99 (a)
(Mus musculus)
Mammalia Mir136 36
  • 99 (a)
(Pan troglodytes)
Mammalia ptr-mir-136 36
  • 100 (a)
Species with no ortholog for MIR136:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR136 Gene

Gene Tree for MIR136 (if available)
Gene Tree for MIR136 (if available)

Paralogs for MIR136 Gene

No data available for Paralogs for MIR136 Gene

Variants for MIR136 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR136 Gene

Variant ID Type Subtype PubMed ID
nsv902240 CNV Loss 21882294
nsv509549 CNV Insertion 20534489
nsv902241 CNV Loss 21882294

Relevant External Links for MIR136 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR136 Gene

Disorders for MIR136 Gene

Relevant External Links for MIR136

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR136: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR136 Gene

Publications for MIR136 Gene

  1. miR-136 modulates TGF-I^1-induced proliferation arrest by targeting PPP2R2A in keratinocytes. (PMID: 25654102) Zhang D. … Pang X. (Biomed Res Int 2015) 67
  2. Expression of miR-136 is associated with the primary cisplatin resistance of human epithelial ovarian cancer. (PMID: 25482209) Zhao H. … Cui S. (Oncol. Rep. 2015) 67
  3. MicroRNA expression profile of bromocriptine-resistant prolactinomas. (PMID: 25064468) Wu Z.B. … Zhao W.G. (Mol. Cell. Endocrinol. 2014) 67
  4. Upregulation of miR-136 in human non-small cell lung cancer cells promotes Erk1/2 activation by targeting PPP2R2A. (PMID: 23959478) Shen S. … Wang J. (Tumour Biol. 2014) 67
  5. Targeting Smad2 and Smad3 by miR-136 suppresses metastasis-associated traits of lung adenocarcinoma cells. (PMID: 25198664) Yang Y. … Li M. (Oncol. Res. 2013) 67

Products for MIR136 Gene

Sources for MIR136 Gene

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