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Aliases for MIR1343 Gene

Subcategory (RNA class) for MIR1343 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1343 Gene

  • MicroRNA 1343 2 3 5
  • Hsa-Mir-1343 3

External Ids for MIR1343 Gene

Previous GeneCards Identifiers for MIR1343 Gene

  • GC11U901867

Summaries for MIR1343 Gene

Entrez Gene Summary for MIR1343 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1343 Gene

MIR1343 (MicroRNA 1343) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1343 Gene

Genomics for MIR1343 Gene

Regulatory Elements for MIR1343 Gene

Enhancers for MIR1343 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G035006 2 FANTOM5 Ensembl ENCODE dbSUPER 11.4 +69.0 68970 9.8 PKNOX1 CREB3L1 FEZF1 CBX5 ZNF207 FOS DEK JUNB TBX21 ZNF592 APIP CD44 PDHX LOC100507144 MIR1343 PAMR1 GC11M035009 GC11P034975
GH11G035336 2 FANTOM5 Ensembl ENCODE dbSUPER 11 +396.0 396006 2.9 FOXA2 CREB3L1 MLX SIN3A ARID4B DMAP1 YY1 ZNF766 FOS SP5 CD44 MIR1343 ENSG00000255004 ENSG00000215380
GH11G035157 1.9 FANTOM5 Ensembl ENCODE dbSUPER 11.2 +224.9 224919 18.5 PKNOX1 FOXA2 WRNIP1 YY1 GATA2 ELK1 CBX5 FOS JUNB PPARG CD44 LOC100507144 MIR1343 PDHX APIP ENSG00000255004 GC11P035210
GH11G035313 1.8 FANTOM5 Ensembl ENCODE dbSUPER 11 +371.9 371861 1.3 PKNOX1 TBL1XR1 BMI1 CBX5 RELB ETV6 IKZF2 CREM CBFB CEBPB ENSG00000255004 CD44 MIR1343 SLC1A2 ENSG00000215380
GH11G035329 1.7 FANTOM5 Ensembl ENCODE dbSUPER 11 +389.3 389267 2.4 HDGF ATF1 CBX3 WRNIP1 TCF12 ZNF766 FOS CREM DEK CEBPB ENSG00000255004 MIR1343 ENSG00000215380
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1343 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1343 Gene

Chromosome:
11
Start:
34,941,837 bp from pter
End:
34,941,920 bp from pter
Size:
84 bases
Orientation:
Plus strand

Genomic View for MIR1343 Gene

Genes around MIR1343 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1343 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1343 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1343 Gene

Proteins for MIR1343 Gene

Post-translational modifications for MIR1343 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1343 Gene

Domains & Families for MIR1343 Gene

Gene Families for MIR1343 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1343: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1343 Gene

Function for MIR1343 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1343 Gene

Localization for MIR1343 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1343 Gene

Pathways & Interactions for MIR1343 Gene

SuperPathways for MIR1343 Gene

No Data Available

Interacting Proteins for MIR1343 Gene

Gene Ontology (GO) - Biological Process for MIR1343 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1343 Gene

Drugs & Compounds for MIR1343 Gene

No Compound Related Data Available

Transcripts for MIR1343 Gene

mRNA/cDNA for MIR1343 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1343 Gene

No ASD Table

Relevant External Links for MIR1343 Gene

GeneLoc Exon Structure for
MIR1343
ECgene alternative splicing isoforms for
MIR1343

Expression for MIR1343 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1343 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1343 Gene:

MIR1343
genes like me logo Genes that share expression patterns with MIR1343: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1343 Gene

Orthologs for MIR1343 Gene

Evolution for MIR1343 Gene

ENSEMBL:
Gene Tree for MIR1343 (if available)
TreeFam:
Gene Tree for MIR1343 (if available)

No data available for Orthologs for MIR1343 Gene

Paralogs for MIR1343 Gene

No data available for Paralogs for MIR1343 Gene

Variants for MIR1343 Gene

Sequence variations from dbSNP and Humsavar for MIR1343 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1001577601 -- 34,940,193(+) CCATC(A/G)AGCAC intron-variant, upstream-variant-2KB
rs1004236727 -- 34,939,853(+) AATTA(G/T)TACAG intron-variant, upstream-variant-2KB
rs1004568741 -- 34,942,364(+) AAAGT(A/G)TTACA intron-variant, downstream-variant-500B
rs1004871628 -- 34,939,965(+) AGGGG(G/T)CATGT intron-variant, upstream-variant-2KB
rs1005007605 -- 34,940,254(+) TGGTG(C/G)TTGTT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1343 Gene

Variant ID Type Subtype PubMed ID
esv2759817 CNV loss 17122850
nsv1042014 CNV loss 25217958
nsv832119 CNV gain 17160897

Relevant External Links for MIR1343 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1343

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1343 Gene

Disorders for MIR1343 Gene

Relevant External Links for MIR1343

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1343

No disorders were found for MIR1343 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1343 Gene

Publications for MIR1343 Gene

  1. miR-1343 attenuates pathways of fibrosis by targeting the TGF-I^ receptors. (PMID: 26542979) Stolzenburg L.R. … Harris A. (Biochem. J. 2016) 3 64
  2. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J. … Kaessmann H. (Genome Res. 2013) 3 64
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1343 Gene

Sources for MIR1343 Gene

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