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Aliases for MIR1307 Gene

Subcategory (RNA class) for MIR1307 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1307 Gene

  • MicroRNA 1307 2 3 5
  • Hsa-Mir-1307 3
  • Mir-1307 3
  • MIRN1307 3

External Ids for MIR1307 Gene

Previous HGNC Symbols for MIR1307 Gene

  • MIRN1307

Previous GeneCards Identifiers for MIR1307 Gene

  • GC00U923162
  • GC10M105145

Summaries for MIR1307 Gene

Entrez Gene Summary for MIR1307 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1307 Gene

MIR1307 (MicroRNA 1307) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins..

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1307 Gene

Genomics for MIR1307 Gene

Regulatory Elements for MIR1307 Gene

Enhancers for MIR1307 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10G103349 1 ENCODE 11.5 +43.5 43502 1.9 HDGF ZNF133 SIN3A DMAP1 GLI4 ZNF2 ZNF48 ETS1 GLIS2 ZNF143 SLK MIR1307 PDCD11 USMG5 RNU11-3P ENSG00000260461 NEURL1-AS1 CALHM2 PCGF6 GC10M103313
GH10G103244 1 Ensembl ENCODE 9.9 +149.6 149634 0.3 CTCF ARID4B MAX CEBPG ZNF2 RAD21 RFX5 TEAD3 ZNF143 SMC3 INA RNU11-3P CNNM2 CYP17A1 MIR1307 USMG5 PDCD11 AS3MT PTGES3P4 PFN1P11
GH10G103417 0.6 ENCODE 11.7 -22.6 -22618 0.2 CTCF ZNF654 TRIM22 SMC3 REST RAD21 ENSG00000234699 CALHM2 NEURL1 PDCD11 USMG5 MIR1307 CALHM1 NEURL1-AS1 GC10M103406 ENSG00000273485
GH10G103416 0.4 ENCODE 11.7 -22.4 -22418 0.2 CTCF TRIM22 CALHM2 ENSG00000234699 NEURL1 USMG5 PDCD11 MIR1307 CALHM1 NEURL1-AS1 GC10M103406 ENSG00000273485
GH10G103432 0.4 dbSUPER 11 -37.9 -37904 0.4 FOXA3 FOXA1 CALHM1 NEURL1 MIR1307 PDCD11 USMG5 NEURL1-AS1 RNU11-3P ENSG00000273485 GC10M103406
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1307 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1307 Gene

Chromosome:
10
Start:
103,394,253 bp from pter
End:
103,394,401 bp from pter
Size:
149 bases
Orientation:
Minus strand

Genomic View for MIR1307 Gene

Genes around MIR1307 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1307 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1307 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1307 Gene

ORGUL Member Location for MIR1307 Gene

ORGUL Member Location for MIR1307 gene

Proteins for MIR1307 Gene

Post-translational modifications for MIR1307 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1307 Gene

Domains & Families for MIR1307 Gene

Gene Families for MIR1307 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1307: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1307 Gene

Function for MIR1307 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1307 Gene

Localization for MIR1307 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1307 Gene

Pathways & Interactions for MIR1307 Gene

genes like me logo Genes that share pathways with MIR1307: view

Pathways by source for MIR1307 Gene

1 BioSystems pathway for MIR1307 Gene

Interacting Proteins for MIR1307 Gene

Gene Ontology (GO) - Biological Process for MIR1307 Gene

None

No data available for SIGNOR curated interactions for MIR1307 Gene

Drugs & Compounds for MIR1307 Gene

No Compound Related Data Available

Transcripts for MIR1307 Gene

mRNA/cDNA for MIR1307 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1307 Gene

No ASD Table

Relevant External Links for MIR1307 Gene

GeneLoc Exon Structure for
MIR1307
ECgene alternative splicing isoforms for
MIR1307

Expression for MIR1307 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1307 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1307 Gene:

MIR1307
genes like me logo Genes that share expression patterns with MIR1307: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1307 Gene

Orthologs for MIR1307 Gene

Evolution for MIR1307 Gene

ENSEMBL:
Gene Tree for MIR1307 (if available)
TreeFam:
Gene Tree for MIR1307 (if available)

No data available for Orthologs for MIR1307 Gene

Paralogs for MIR1307 Gene

No data available for Paralogs for MIR1307 Gene

Variants for MIR1307 Gene

Sequence variations from dbSNP and Humsavar for MIR1307 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1000296052 -- 103,395,727(+) TTTCC(C/T)TTCTA intron-variant, upstream-variant-2KB
rs1005865989 -- 103,395,124(+) GGAAC(A/G)GGATT intron-variant, upstream-variant-2KB
rs1006106242 -- 103,394,807(+) CTTAG(A/G)GTTTG intron-variant, upstream-variant-2KB
rs1006876211 -- 103,396,365(+) TGCAA(A/C)GTGCA intron-variant, upstream-variant-2KB
rs1007108534 -- 103,396,112(+) TACGT(C/T)ACTGG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1307 Gene

Variant ID Type Subtype PubMed ID
dgv280e212 CNV gain 25503493
dgv965n100 CNV gain 25217958
dgv966n100 CNV gain 25217958
esv3577694 CNV gain 25503493
esv3624413 CNV gain 21293372
nsv7529 CNV insertion 18451855

Relevant External Links for MIR1307 Gene

Human Gene Mutation Database (HGMD)
MIR1307
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1307

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1307 Gene

Disorders for MIR1307 Gene

Relevant External Links for MIR1307

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1307

No disorders were found for MIR1307 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1307 Gene

Publications for MIR1307 Gene

  1. MiR-1307 promotes ovarian cancer cell chemoresistance by targeting the ING5 expression. (PMID: 28086946) Chen W.T. … Yang B. (J Ovarian Res 2017) 3 64
  2. miR-1307 promotes the proliferation of prostate cancer by targeting FOXO3A. (PMID: 28122308) Qiu X. … Dou Y. (Biomed. Pharmacother. 2017) 3 64
  3. The clinicopathological significance of miR-1307 in chemotherapy resistant epithelial ovarian cancer. (PMID: 25887170) Zhou Y. … Shuang T. (J Ovarian Res 2015) 3 64
  4. The polymorphic terminal-loop of pre-miR-1307 binding with MBNL1 contributes to colorectal carcinogenesis via interference with Dicer1 recruitment. (PMID: 25977444) Tang R. … Wang W. (Carcinogenesis 2015) 3 64
  5. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. (PMID: 23974872) Ripke S. … Sullivan P.F. (Nat. Genet. 2013) 3 64

Products for MIR1307 Gene

Sources for MIR1307 Gene

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