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Aliases for MIR1307 Gene

Subcategory (RNA class) for MIR1307 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1307 Gene

  • MicroRNA 1307 2 3
  • USMG5 4 5
  • Up-Regulated During Skeletal Muscle Growth 5 Homolog (Mouse) 5
  • Diabetes-Associated Protein In Insulin-Sensitive Tissues 4
  • HCV F-Transactivated Protein 2 4
  • Hsa-Mir-1307 3
  • Mir-1307 3
  • MIRN1307 3
  • HCVFTP2 4
  • DAPIT 4

External Ids for MIR1307 Gene

Previous HGNC Symbols for MIR1307 Gene

  • MIRN1307

Previous GeneCards Identifiers for MIR1307 Gene

  • GC00U923162
  • GC10M105145

Summaries for MIR1307 Gene

Entrez Gene Summary for MIR1307 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1307 Gene

MIR1307 (MicroRNA 1307) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins..

UniProtKB/Swiss-Prot for MIR1307 Gene

  • Plays a critical role in maintaining the ATP synthase population in mitochondria.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1307 Gene

Genomics for MIR1307 Gene

Regulatory Elements for MIR1307 Gene

Enhancers for MIR1307 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10F103416 0.5 ENCODE 11.7 -20.4 -20353 0.2 CTCF TRIM22 ENSG00000234699 CALHM2 NEURL1 PDCD11 USMG5 MIR1307 CALHM1 NEURL1-AS1 GC10M103406 ENSG00000273485
GH10F103417 0.7 ENCODE 11.7 -20.6 -20553 0.2 CTCF ZNF654 SMC3 TRIM22 REST RAD21 ENSG00000234699 CALHM2 NEURL1 PDCD11 USMG5 MIR1307 CALHM1 NEURL1-AS1 GC10M103406 ENSG00000273485
GH10F103350 0.5 ENCODE 11.5 +45.6 45567 1.9 ZNF133 SIN3A GLI4 DMAP1 ZNF48 ZNF2 ETS1 GLIS2 ZNF143 ZNF263 SLK USMG5 PDCD11 MIR1307 ENSG00000260461 RNU11-3P NEURL1-AS1 CALHM2 PCGF6 GC10M103313
GH10F103433 0.2 ENCODE 11 -37.6 -37593 0.2 CALHM1 NEURL1 USMG5 MIR1307 PDCD11 NEURL1-AS1 RNU11-3P ENSG00000273485 GC10M103406
GH10F103244 0.8 Ensembl ENCODE 9.9 +151.6 151566 0.6 CTCF ARID4B MAX CEBPG ZNF2 RAD21 RFX5 TEAD3 ZNF143 SMC3 INA RNU11-3P CNNM2 CYP17A1 USMG5 PDCD11 MIR1307 AS3MT PTGES3P4 PFN1P11
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR1307 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1307 Gene

Chromosome:
10
Start:
103,389,041 bp from pter
End:
103,396,466 bp from pter
Size:
7,426 bases
Orientation:
Minus strand

Genomic View for MIR1307 Gene

Genes around MIR1307 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1307 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1307 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1307 Gene

Proteins for MIR1307 Gene

  • Protein details for MIR1307 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96IX5-USMG5_HUMAN
    Recommended name:
    Up-regulated during skeletal muscle growth protein 5
    Protein Accession:
    Q96IX5
    Secondary Accessions:
    • B2R4N2
    • D3DR92

    Protein attributes for MIR1307 Gene

    Size:
    58 amino acids
    Molecular mass:
    6458 Da
    Quaternary structure:
    • Component of an ATP synthase complex composed of ATP5F1, ATP5G1, ATP5E, ATP5H, ATP5I, ATP5J, ATP5J2, MT-ATP6, MT-ATP8, ATP5A1, ATP5B, ATP5D, ATP5C1, ATP5O, ATP5L, USMG5 and MP68.
    • Component of an ATP synthase complex composed of ATP5F1, ATP5G1, ATP5E, ATP5H, ATP5I, ATP5J, ATP5J2, MT-ATP6, MT-ATP8, ATP5A1, ATP5B, ATP5D, ATP5C1, ATP5O, ATP5L, USMG5 and MP68.

neXtProt entry for MIR1307 Gene

Post-translational modifications for MIR1307 Gene

  • Ubiquitination at Lys 17
  • Modification sites at PhosphoSitePlus

Other Protein References for MIR1307 Gene

No data available for DME Specific Peptides for MIR1307 Gene

Domains & Families for MIR1307 Gene

Gene Families for MIR1307 Gene

Protein Domains for MIR1307 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1307: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1307 Gene

Function for MIR1307 Gene

Molecular function for MIR1307 Gene

UniProtKB/Swiss-Prot Function:
Plays a critical role in maintaining the ATP synthase population in mitochondria.
UniProtKB/Swiss-Prot Induction:
Transactivated by SBP1.

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1307 Gene

Localization for MIR1307 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MIR1307 Gene

Mitochondrion membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for MIR1307 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005743 mitochondrial inner membrane IEA --
GO:0005753 mitochondrial proton-transporting ATP synthase complex IBA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0031966 mitochondrial membrane IEA --
genes like me logo Genes that share ontologies with MIR1307: view

No data available for Subcellular locations from COMPARTMENTS for MIR1307 Gene

Pathways & Interactions for MIR1307 Gene

genes like me logo Genes that share pathways with MIR1307: view

Pathways by source for MIR1307 Gene

1 BioSystems pathway for MIR1307 Gene

Gene Ontology (GO) - Biological Process for MIR1307 Gene

None

No data available for SIGNOR curated interactions for MIR1307 Gene

Transcripts for MIR1307 Gene

mRNA/cDNA for MIR1307 Gene

(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1307 Gene

No ASD Table

Relevant External Links for MIR1307 Gene

GeneLoc Exon Structure for
MIR1307
ECgene alternative splicing isoforms for
MIR1307

Expression for MIR1307 Gene

mRNA expression in normal human tissues for MIR1307 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1307 Gene:

MIR1307
genes like me logo Genes that share expression patterns with MIR1307: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1307 Gene

Orthologs for MIR1307 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR1307 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia USMG5 35
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia USMG5 35 35
  • 95 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Usmg5 35
  • 90 (a)
OneToOne
dog
(Canis familiaris)
Mammalia USMG5 35
  • 86 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia USMG5 35
  • 81 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia USMG5 35
  • 77 (a)
OneToOne
chicken
(Gallus gallus)
Aves USMG5 35
  • 64 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii USMG5 35
  • 64 (a)
OneToOne
Species where no ortholog for MIR1307 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR1307 Gene

ENSEMBL:
Gene Tree for MIR1307 (if available)
TreeFam:
Gene Tree for MIR1307 (if available)

Paralogs for MIR1307 Gene

Pseudogenes.org Pseudogenes for MIR1307 Gene

genes like me logo Genes that share paralogs with MIR1307: view

No data available for Paralogs for MIR1307 Gene

Variants for MIR1307 Gene

Sequence variations from dbSNP and Humsavar for MIR1307 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs111726888 -- 103,395,524(+) AACTC(C/T)GGACC intron-variant, upstream-variant-2KB
rs11191675 -- 103,394,661(+) TCTTA(A/G)CCAAC intron-variant, upstream-variant-2KB
rs11191676 -- 103,395,309(+) ACTGC(A/C)CTTCT intron-variant, upstream-variant-2KB
rs113446829 -- 103,395,205(+) TTAGG(C/G)CAAAG intron-variant, upstream-variant-2KB
rs118060510 -- 103,395,146(+) GATAA(C/T)GGAGT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1307 Gene

Variant ID Type Subtype PubMed ID
dgv280e212 CNV gain 25503493
dgv965n100 CNV gain 25217958
dgv966n100 CNV gain 25217958
esv3577694 CNV gain 25503493
esv3624413 CNV gain 21293372
nsv7529 CNV insertion 18451855

Relevant External Links for MIR1307 Gene

Human Gene Mutation Database (HGMD)
MIR1307
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1307

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1307 Gene

Disorders for MIR1307 Gene

Relevant External Links for MIR1307

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1307

No disorders were found for MIR1307 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1307 Gene

Publications for MIR1307 Gene

  1. The clinicopathological significance of miR-1307 in chemotherapy resistant epithelial ovarian cancer. (PMID: 25887170) Zhou Y. … Shuang T. (J Ovarian Res 2015) 3 64
  2. The polymorphic terminal-loop of pre-miR-1307 binding with MBNL1 contributes to colorectal carcinogenesis via interference with Dicer1 recruitment. (PMID: 25977444) Tang R. … Wang W. (Carcinogenesis 2015) 3 64
  3. N-terminome analysis of the human mitochondrial proteome. (PMID: 25944712) Vaca Jacome A.S. … Carapito C. (Proteomics 2015) 4 64
  4. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. (PMID: 23974872) Ripke S. … Sullivan P.F. (Nat. Genet. 2013) 3 64
  5. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64

Products for MIR1307 Gene

Sources for MIR1307 Gene

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