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Aliases for MIR1303 Gene

Subcategory (RNA class) for MIR1303 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1303 Gene

  • MicroRNA 1303 2 3 5
  • Hsa-Mir-1303 3
  • MIRN1303 3

External Ids for MIR1303 Gene

Previous HGNC Symbols for MIR1303 Gene

  • MIRN1303

Previous GeneCards Identifiers for MIR1303 Gene

  • GC00U923081
  • GC05P154046

Summaries for MIR1303 Gene

Entrez Gene Summary for MIR1303 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1303 Gene

MIR1303 (MicroRNA 1303) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1303 Gene

Genomics for MIR1303 Gene

Regulatory Elements for MIR1303 Gene

Enhancers for MIR1303 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05F154646 1.3 Ensembl ENCODE 12.4 -37.8 -37774 2.8 PKNOX1 ATF1 ARNT MLX ARID4B DMAP1 ZNF48 GATA2 ZNF143 NCOA1 MIR1303 GEMIN5 CNOT8 LARP1 GC05P154654 GC05M154594
GH05F154778 1.2 Ensembl ENCODE 11.7 +97.7 97725 10.2 PKNOX1 ZFP64 SIN3A FEZF1 ZNF2 GLIS2 FOS ZNF263 TSHZ1 SMARCA4 CNOT8 LARP1 FAXDC2 MIR1303 GC05M154784 GC05P154730
GH05F154752 1.2 ENCODE 11.5 +71.7 71707 9.1 HDGF PKNOX1 CREB3L1 MLX WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 LARP1 CNOT8 MIR1303 GEMIN5 SAP30L-AS1 GC05M154784 GC05P154730
GH05F154764 1.1 Ensembl ENCODE 11.1 +82.5 82491 7.7 CTCF PKNOX1 SIN3A ZNF384 ZNF121 ZFHX2 ZNF366 POLR2A PRDM10 ZNF600 CNOT8 LARP1 FAXDC2 MIR1303 HAND1 GC05M154784 GC05P154730
GH05F154708 0.9 Ensembl ENCODE 11.9 +23.3 23326 0.6 SOX13 SOX5 CEBPB MAX USF2 JUND ATF3 CEBPA FOS ZNF18 LARP1 MIR1303 ENSG00000274472 RN7SL803P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1303 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1303 Gene

Chromosome:
5
Start:
154,685,776 bp from pter
End:
154,685,861 bp from pter
Size:
86 bases
Orientation:
Plus strand

Genomic View for MIR1303 Gene

Genes around MIR1303 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1303 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1303 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1303 Gene

Proteins for MIR1303 Gene

Post-translational modifications for MIR1303 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1303 Gene

Domains & Families for MIR1303 Gene

Gene Families for MIR1303 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1303: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1303 Gene

Function for MIR1303 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1303 Gene

Localization for MIR1303 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1303 Gene

Pathways & Interactions for MIR1303 Gene

SuperPathways for MIR1303 Gene

No Data Available

Interacting Proteins for MIR1303 Gene

Gene Ontology (GO) - Biological Process for MIR1303 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1303 Gene

Transcripts for MIR1303 Gene

mRNA/cDNA for MIR1303 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1303 Gene

No ASD Table

Relevant External Links for MIR1303 Gene

GeneLoc Exon Structure for
MIR1303
ECgene alternative splicing isoforms for
MIR1303

Expression for MIR1303 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1303 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1303 Gene:

MIR1303
genes like me logo Genes that share expression patterns with MIR1303: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1303 Gene

Orthologs for MIR1303 Gene

Evolution for MIR1303 Gene

ENSEMBL:
Gene Tree for MIR1303 (if available)
TreeFam:
Gene Tree for MIR1303 (if available)

No data available for Orthologs for MIR1303 Gene

Paralogs for MIR1303 Gene

No data available for Paralogs for MIR1303 Gene

Variants for MIR1303 Gene

Sequence variations from dbSNP and Humsavar for MIR1303 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs10073381 -- 154,685,672(+) ccttt(A/G)tgcag intron-variant, upstream-variant-2KB
rs112022253 -- 154,685,246(+) CTCAG(-/A)AAAAA intron-variant, upstream-variant-2KB
rs113185888 -- 154,685,708(+) GGCTC(A/G)CACCT intron-variant, upstream-variant-2KB
rs11372758 -- 154,685,739(+) GCCAA(-/G)GTGGG intron-variant, upstream-variant-2KB
rs113960136 -- 154,685,576(+) ATAGG(A/G)AAGTC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1303 Gene

Variant ID Type Subtype PubMed ID
nsv462491 CNV loss 19166990
nsv600090 CNV loss 21841781

Relevant External Links for MIR1303 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1303

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1303 Gene

Disorders for MIR1303 Gene

Relevant External Links for MIR1303

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1303

No disorders were found for MIR1303 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1303 Gene

Publications for MIR1303 Gene

  1. miR-1303 targets claudin-18 gene to modulate proliferation and invasion of gastric cancer cells. (PMID: 24647998) Zhang S.J. … Zhao G.Q. (Dig. Dis. Sci. 2014) 3 64
  2. Differential expression of microRNAs in plasma of patients with laryngeal squamous cell carcinoma: potential early-detection markers for laryngeal squamous cell carcinoma. (PMID: 23817697) Ayaz L. … Tamer L. (J. Cancer Res. Clin. Oncol. 2013) 3 64
  3. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1303 Gene

Sources for MIR1303 Gene

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