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Aliases for MIR1302-6 Gene

Subcategory (RNA class) for MIR1302-6 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1302-6 Gene

  • MicroRNA 1302-6 2 3 5
  • Hsa-Mir-1302-6 3
  • MIRN1302-6 3

External Ids for MIR1302-6 Gene

Previous HGNC Symbols for MIR1302-6 Gene

  • MIRN1302-6

Previous GeneCards Identifiers for MIR1302-6 Gene

  • GC00U922867

Summaries for MIR1302-6 Gene

Entrez Gene Summary for MIR1302-6 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1302-6 Gene

MIR1302-6 (MicroRNA 1302-6) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1302-6 Gene

Genomics for MIR1302-6 Gene

Regulatory Elements for MIR1302-6 Gene

Enhancers for MIR1302-6 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07G018126 0.7 ENCODE 0.7 +0.9 947 0.1 PKNOX1 L3MBTL2 FEZF1 ZIC2 ZNF843 OSR2 ZSCAN21 HIC1 PRDM6 ZNF366 MIR1302-6 HDAC9
GH07G018177 1.3 Ensembl ENCODE 0.2 -50.9 -50861 2.1 HDGF PKNOX1 ATF1 ARNT TCF12 GTF3C2 ZNF766 GATA2 FOS CAVIN1 HDAC9 MIR1302-6 GC07M018234
GH07G018086 0.7 ENCODE 0.3 +40.3 40257 0.2 PKNOX1 FEZF1 ZIC2 PRDM10 EZH2 L3MBTL2 ZFP37 CHD1 ZNF501 ZNF843 HDAC9 MIR1302-6
GH07G018175 0.9 ENCODE 0.2 -48.8 -48800 1.6 HDAC1 ATF1 CREB3L1 RAD21 CHAMP1 TCF12 GATA2 CEBPB ZEB2 ZNF592 HDAC9 MIR1302-6 GC07M018234
GH07G018317 1.3 FANTOM5 Ensembl ENCODE 0.1 -190.4 -190428 1.2 CTCF JUN ZFP64 MAX RAD21 ZNF697 GATA3 SMC3 FOS CHD2 HDAC9 SNX13 GC07M018234 MIR1302-6
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1302-6 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1302-6 Gene

Chromosome:
7
Start:
18,127,220 bp from pter
End:
18,127,309 bp from pter
Size:
90 bases
Orientation:
Minus strand

Genomic View for MIR1302-6 Gene

Genes around MIR1302-6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1302-6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1302-6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1302-6 Gene

ORGUL Member Location for MIR1302-6 Gene

ORGUL Member Location for MIR1302-6 gene

Proteins for MIR1302-6 Gene

Post-translational modifications for MIR1302-6 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1302-6 Gene

Domains & Families for MIR1302-6 Gene

Gene Families for MIR1302-6 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1302-6: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1302-6 Gene

Function for MIR1302-6 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1302-6 Gene

Localization for MIR1302-6 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1302-6 Gene

Pathways & Interactions for MIR1302-6 Gene

SuperPathways for MIR1302-6 Gene

No Data Available

Interacting Proteins for MIR1302-6 Gene

Gene Ontology (GO) - Biological Process for MIR1302-6 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1302-6 Gene

Drugs & Compounds for MIR1302-6 Gene

No Compound Related Data Available

Transcripts for MIR1302-6 Gene

mRNA/cDNA for MIR1302-6 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1302-6 Gene

No ASD Table

Relevant External Links for MIR1302-6 Gene

GeneLoc Exon Structure for
MIR1302-6
ECgene alternative splicing isoforms for
MIR1302-6

Expression for MIR1302-6 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1302-6 Gene

Orthologs for MIR1302-6 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR1302-6 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-1302-6 35
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 35
  • 52 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 37 (a)
ManyToMany
Species where no ortholog for MIR1302-6 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1302-6 Gene

ENSEMBL:
Gene Tree for MIR1302-6 (if available)
TreeFam:
Gene Tree for MIR1302-6 (if available)

Paralogs for MIR1302-6 Gene

No data available for Paralogs for MIR1302-6 Gene

Variants for MIR1302-6 Gene

Sequence variations from dbSNP and Humsavar for MIR1302-6 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1004696472 -- 18,128,125(+) GTGAA(A/G)CTAAT intron-variant, upstream-variant-2KB
rs1008595975 -- 18,127,881(+) AAACA(A/C)ATTTT intron-variant, upstream-variant-2KB
rs1009240647 -- 18,128,449(+) ATTGA(A/G)TGATA intron-variant, upstream-variant-2KB
rs1010676196 -- 18,126,790(+) TTCCC(C/G)AAATC intron-variant, downstream-variant-500B
rs1011051014 -- 18,129,025(+) CAAGA(C/G)AGAGA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1302-6 Gene

Variant ID Type Subtype PubMed ID
nsv1022746 CNV gain 25217958
nsv1025023 CNV gain 25217958
nsv1027814 CNV gain 25217958
nsv606357 CNV gain 21841781
nsv606358 CNV gain 21841781

Relevant External Links for MIR1302-6 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1302-6

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1302-6 Gene

Disorders for MIR1302-6 Gene

Relevant External Links for MIR1302-6

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1302-6

No disorders were found for MIR1302-6 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1302-6 Gene

Publications for MIR1302-6 Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1302-6 Gene

Sources for MIR1302-6 Gene

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