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Aliases for MIR1302-2 Gene

Subcategory (RNA class) for MIR1302-2 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1302-2 Gene

  • MicroRNA 1302-2 2 3 5
  • Hsa-Mir-1302-2 3
  • MIRN1302-2 3

External Ids for MIR1302-2 Gene

Previous HGNC Symbols for MIR1302-2 Gene

  • MIRN1302-2

Previous GeneCards Identifiers for MIR1302-2 Gene

  • GC00U923098
  • GC01P000021
  • GC09P000030

Summaries for MIR1302-2 Gene

Entrez Gene Summary for MIR1302-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1302-2 Gene

MIR1302-2 (MicroRNA 1302-2) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1302-2 Gene

Genomics for MIR1302-2 Gene

Regulatory Elements for MIR1302-2 Gene

Enhancers for MIR1302-2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F000919 1.3 Ensembl ENCODE 16.2 +890.8 890837 2.4 ATF1 PKNOX1 ARID4B SIN3A FEZF1 GLI4 ZNF48 ZNF2 GLIS2 KLF7 ENSG00000229905 WBP1LP6 ENSG00000235146 MIR1302-2 EGID-729587 DDX11L1 ENSG00000230699 HES4 LINC00115 GC01M000917
GH01F000998 1.2 ENCODE 16.2 +971.1 971086 3.5 CREB3L1 MLX FEZF1 DMAP1 SLC30A9 ZNF143 ZNF263 SP3 NFYC MEF2D ENSG00000230092 WASH7P ENSG00000272512 LOC100288379 CCNL2 PLEKHN1 ENSG00000237094 MIR6727 LOC100288069 ENSG00000240731
GH01F000939 1 ENCODE 16.2 +912.9 912901 6.3 ATF1 PKNOX1 FEZF1 ZNF2 ZNF121 GLIS2 KLF7 ZNF548 KLF13 ZNF263 ENSG00000229905 WBP1LP6 ENSG00000235146 MIR1302-2 CCNL2 NOC2L EGID-729587 LOC100288379 PLEKHN1 ENSG00000241180
GH01F000925 0.9 ENCODE 16.2 +896.1 896122 0.2 INSM2 ZNF76 KLF17 GLIS2 ZNF366 SCRT2 KLF7 ZNF391 EGR2 SP3 ENSG00000229905 WBP1LP6 ENSG00000235146 MIR1302-2 EGID-729587 DDX11L1 LINC01128 SAMD11 GC01M000926
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1302-2 on UCSC Golden Path with GeneCards custom track

Promoters for MIR1302-2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001740671 -354 2001

Genomic Location for MIR1302-2 Gene

Chromosome:
1
Start:
29,554 bp from pter
End:
31,109 bp from pter
Size:
1,556 bases
Orientation:
Plus strand

Genomic View for MIR1302-2 Gene

Genes around MIR1302-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1302-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1302-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1302-2 Gene

Proteins for MIR1302-2 Gene

Post-translational modifications for MIR1302-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1302-2 Gene

Domains & Families for MIR1302-2 Gene

Gene Families for MIR1302-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1302-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1302-2 Gene

Function for MIR1302-2 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1302-2 Gene

Localization for MIR1302-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1302-2 Gene

Pathways & Interactions for MIR1302-2 Gene

SuperPathways for MIR1302-2 Gene

No Data Available

Interacting Proteins for MIR1302-2 Gene

Gene Ontology (GO) - Biological Process for MIR1302-2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1302-2 Gene

Transcripts for MIR1302-2 Gene

mRNA/cDNA for MIR1302-2 Gene

(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1302-2 Gene

No ASD Table

Relevant External Links for MIR1302-2 Gene

GeneLoc Exon Structure for
MIR1302-2
ECgene alternative splicing isoforms for
MIR1302-2

Expression for MIR1302-2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1302-2 Gene

mRNA differential expression in normal tissues according to GTEx for MIR1302-2 Gene

This gene is overexpressed in Testis (x7.4).
genes like me logo Genes that share expression patterns with MIR1302-2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1302-2 Gene

Orthologs for MIR1302-2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR1302-2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-1302-3 35 35
  • 99 (a)
ManyToMany
ptr-mir-1302-5 35
  • 97 (a)
ManyToMany
ptr-mir-1302-2 35
  • 96 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 72 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 67 (a)
OneToMany
Species where no ortholog for MIR1302-2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1302-2 Gene

ENSEMBL:
Gene Tree for MIR1302-2 (if available)
TreeFam:
Gene Tree for MIR1302-2 (if available)

Paralogs for MIR1302-2 Gene

No data available for Paralogs for MIR1302-2 Gene

Variants for MIR1302-2 Gene

Sequence variations from dbSNP and Humsavar for MIR1302-2 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs11490932 -- 29,720(+) GCCCT(C/T)GCCCG upstream-variant-2KB
rs11794875 -- 29,757(+) GCCCA(C/G)GCCCA upstream-variant-2KB
rs145198531 -- 28,591(+) GGTTT(-/GGT)TTTTT intron-variant, upstream-variant-2KB
rs17040995 -- 28,959(+) CCGGC(A/C)GGGGC intron-variant, upstream-variant-2KB
rs2462493 -- 29,436(+) CGCTC(A/G)CCCTC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1302-2 Gene

Variant ID Type Subtype PubMed ID
nsv982357 CNV duplication 23825009
nsv982187 CNV duplication 23825009
nsv977807 CNV duplication 23825009
nsv977765 CNV duplication 23825009
nsv9651 CNV gain+loss 18304495
nsv961258 CNV duplication 23825009
nsv960766 CNV duplication 23825009
nsv952893 CNV duplication 24416366
nsv945699 CNV duplication 23825009
nsv9315 CNV gain+loss 18304495
nsv8400 CNV gain+loss 18304495
nsv820962 CNV duplication 20802225
nsv820527 CNV duplication 20802225
nsv7879 CNV gain+loss 18304495
nsv570923 CNV gain 21841781
nsv482937 CNV loss 15286789
nsv471591 CNV loss 15918152
nsv471523 CNV gain 19718026
nsv471520 CNV gain 19718026
nsv469759 CNV gain 16826518
nsv428112 CNV gain 18775914
nsv1695 CNV insertion 18451855
nsv1148144 CNV duplication 26484159
nsv1147785 CNV duplication 26484159
nsv1147468 CNV duplication 26484159
nsv1076458 CNV duplication 25765185
nsv1076307 CNV duplication 25765185
nsv1075907 CNV duplication 25765185
esv994482 CNV gain 20482838
esv3433926 CNV duplication 20981092
esv27561 CNV gain 19812545
esv27265 CNV gain+loss 19812545
esv23366 CNV gain+loss 19812545
esv22059 CNV gain+loss 19812545
dgv4273e59 CNV duplication 20981092
dgv3939n106 CNV duplication 24896259
dgv1e59 CNV duplication 20981092
dgv1957e59 CNV duplication 20981092
dgv1956e59 CNV duplication 20981092
dgv1664n106 CNV duplication 24896259
dgv1278n106 CNV duplication 24896259

Relevant External Links for MIR1302-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1302-2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1302-2 Gene

Disorders for MIR1302-2 Gene

Relevant External Links for MIR1302-2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1302-2

No disorders were found for MIR1302-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1302-2 Gene

Publications for MIR1302-2 Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1302-2 Gene

Sources for MIR1302-2 Gene

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