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Aliases for MIR1299 Gene

Subcategory (RNA class) for MIR1299 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1299 Gene

  • MicroRNA 1299 2 3 5
  • Hsa-Mir-1299 3
  • MIRN1299 3

External Ids for MIR1299 Gene

Previous HGNC Symbols for MIR1299 Gene

  • MIRN1299

Previous GeneCards Identifiers for MIR1299 Gene

  • GC00U923157
  • GC09M068294
  • GC09M069002

Summaries for MIR1299 Gene

Entrez Gene Summary for MIR1299 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1299 Gene

MIR1299 (MicroRNA 1299) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1299 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1299 Gene

Genomics for MIR1299 Gene

Genomic Locations for MIR1299 Gene

Genomic Locations for MIR1299 Gene
chr9:40,929,010-40,929,092
(GRCh38/hg38)
Size:
83 bases
Orientation:
Minus strand
chr9:69,002,239-69,002,321
(GRCh37/hg19)

Genomic View for MIR1299 Gene

Genes around MIR1299 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1299 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1299 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1299 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR1299 Gene

Proteins for MIR1299 Gene

Post-translational modifications for MIR1299 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1299 Gene

Domains & Families for MIR1299 Gene

Gene Families for MIR1299 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1299: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1299 Gene

Function for MIR1299 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1299 Gene

Localization for MIR1299 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1299 Gene

Pathways & Interactions for MIR1299 Gene

SuperPathways for MIR1299 Gene

No Data Available

Interacting Proteins for MIR1299 Gene

Gene Ontology (GO) - Biological Process for MIR1299 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1299 Gene

Drugs & Compounds for MIR1299 Gene

No Compound Related Data Available

Transcripts for MIR1299 Gene

mRNA/cDNA for MIR1299 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1299 Gene

No ASD Table

Relevant External Links for MIR1299 Gene

GeneLoc Exon Structure for
MIR1299
ECgene alternative splicing isoforms for
MIR1299

Expression for MIR1299 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1299 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1299 Gene:

MIR1299
genes like me logo Genes that share expression patterns with MIR1299: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1299 Gene

Orthologs for MIR1299 Gene

Evolution for MIR1299 Gene

ENSEMBL:
Gene Tree for MIR1299 (if available)
TreeFam:
Gene Tree for MIR1299 (if available)

No data available for Orthologs for MIR1299 Gene

Paralogs for MIR1299 Gene

No data available for Paralogs for MIR1299 Gene

Variants for MIR1299 Gene

Sequence variations from dbSNP and Humsavar for MIR1299 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1001884504 -- 40,929,710(-) G/A upstream_transcript_variant
rs1003162598 -- 40,930,454(-) G/A upstream_transcript_variant
rs1003291882 -- 40,930,475(-) G/C upstream_transcript_variant
rs1003498891 -- 40,930,357(-) G/A upstream_transcript_variant
rs1005054600 -- 40,931,026(-) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1299 Gene

Variant ID Type Subtype PubMed ID
dgv4409e59 CNV duplication 20981092
esv22155 CNV gain 19812545
esv3380434 CNV duplication 20981092
esv3388621 CNV duplication 20981092
nsv1019779 CNV loss 25217958
nsv1078079 CNV duplication 25765185
nsv1110566 CNV duplication 24896259
nsv1115828 CNV duplication 24896259
nsv1151999 CNV duplication 26484159
nsv951490 CNV duplication 24416366

Additional Variant Information for MIR1299 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1299

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1299 Gene

Disorders for MIR1299 Gene

Additional Disease Information for MIR1299

No disorders were found for MIR1299 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1299 Gene

Publications for MIR1299 Gene

  1. miR-1299 suppresses cell proliferation of hepatocellular carcinoma (HCC) by targeting CDK6. (PMID: 27490780) Zhu H … Ma J (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016) 3 58
  2. Detection of Differentially Expressed MicroRNAs in Rheumatic Heart Disease: miR-1183 and miR-1299 as Potential Diagnostic Biomarkers. (PMID: 26539505) Li N … Shao G (BioMed research international 2015) 3 58
  3. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
  5. MicroRNA-1299 is a negative regulator of STAT3 in colon cancer. (PMID: 28498395) Wang Y … Zhao W (Oncology reports 2017) 3

Products for MIR1299 Gene

Sources for MIR1299 Gene

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