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Aliases for MIR1298 Gene

Subcategory (RNA class) for MIR1298 Gene

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Quality Score for this RNA gene is

3

Aliases for MIR1298 Gene

  • MicroRNA 1298 2 3 5
  • Hsa-Mir-1298 3
  • MIRN1298 3

External Ids for MIR1298 Gene

ORGUL Members for MIR1298 Gene

Previous HGNC Symbols for MIR1298 Gene

  • MIRN1298

Previous GeneCards Identifiers for MIR1298 Gene

  • GC00U922998
  • GC0XP113856
  • GC0XP113949

Summaries for MIR1298 Gene

Entrez Gene Summary for MIR1298 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1298 Gene

MIR1298 (MicroRNA 1298) is an RNA Gene, and is affiliated with the undefined RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1298 Gene

Genomics for MIR1298 Gene

Genomic Location for MIR1298 Gene

Chromosome:
X
Start:
114,715,233 bp from pter
End:
114,715,344 bp from pter
Size:
112 bases
Orientation:
Plus strand

Genomic View for MIR1298 Gene

Genes around MIR1298 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1298 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1298 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1298 Gene

No data available for Regulatory Elements for MIR1298 Gene

Proteins for MIR1298 Gene

Post-translational modifications for MIR1298 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1298 Gene

Domains & Families for MIR1298 Gene

Gene Families for MIR1298 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1298: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1298 Gene

Function for MIR1298 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1298 Gene

Localization for MIR1298 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1298 Gene

Pathways & Interactions for MIR1298 Gene

SuperPathways for MIR1298 Gene

No Data Available

Interacting Proteins for MIR1298 Gene

Gene Ontology (GO) - Biological Process for MIR1298 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1298 Gene

Transcripts for MIR1298 Gene

mRNA/cDNA for MIR1298 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1298 Gene

No ASD Table

Relevant External Links for MIR1298 Gene

GeneLoc Exon Structure for
MIR1298
ECgene alternative splicing isoforms for
MIR1298

Expression for MIR1298 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1298 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1298 Gene:

MIR1298
genes like me logo Genes that share expression patterns with MIR1298: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1298 Gene

Orthologs for MIR1298 Gene

Evolution for MIR1298 Gene

ENSEMBL:
Gene Tree for MIR1298 (if available)
TreeFam:
Gene Tree for MIR1298 (if available)

No data available for Orthologs for MIR1298 Gene

Paralogs for MIR1298 Gene

No data available for Paralogs for MIR1298 Gene

Variants for MIR1298 Gene

Sequence variations from dbSNP and Humsavar for MIR1298 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs12396612 -- 114,715,707(+) AAGAT(A/G)TCTAA intron-variant, downstream-variant-500B
rs138744202 -- 114,713,586(+) AGAAG(C/T)AAAAA intron-variant, upstream-variant-2KB
rs143529293 -- 114,714,575(+) CTTTC(A/G)AACAA intron-variant, upstream-variant-2KB
rs148035126 -- 114,714,600(+) TGAAT(C/G)CTATG intron-variant, upstream-variant-2KB
rs150861983 -- 114,715,059(+) TTTAT(A/G)AGTTG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1298 Gene

Variant ID Type Subtype PubMed ID
esv33994 CNV gain+loss 17666407
nsv507990 OTHER sequence alteration 20534489
nsv527347 CNV gain 19592680

Relevant External Links for MIR1298 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1298

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1298 Gene

Disorders for MIR1298 Gene

Relevant External Links for MIR1298

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1298

No disorders were found for MIR1298 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1298 Gene

Publications for MIR1298 Gene

  1. MicroRNA-1298 is regulated by DNA methylation and affects vascular smooth muscle cell function by targeting connexin 43. (PMID: 26025955) Hu W. … Wang S. (Cardiovasc. Res. 2015) 3 64
  2. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J. … Kaessmann H. (Genome Res. 2013) 3 64
  3. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
  5. Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. (PMID: 16954537) Berezikov E. … Cuppen E. (Genome Res. 2006) 3 64

Products for MIR1298 Gene

Sources for MIR1298 Gene

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