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Aliases for MIR1297 Gene

Subcategory (RNA class) for MIR1297 Gene


Quality Score for this RNA gene is


Aliases for MIR1297 Gene

  • MicroRNA 1297 2 3
  • Hsa-Mir-1297 3
  • Mir-1297 3
  • MIRN1297 3

External Ids for MIR1297 Gene

Previous HGNC Symbols for MIR1297 Gene

  • MIRN1297

Previous GeneCards Identifiers for MIR1297 Gene

  • GC00U922917
  • GC13M053784
  • GC13M054886

Summaries for MIR1297 Gene

Entrez Gene Summary for MIR1297 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1297 Gene

MIR1297 (MicroRNA 1297) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1297 Gene

Genomics for MIR1297 Gene

Regulatory Elements for MIR1297 Gene

Enhancers for MIR1297 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR1297 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1297 Gene

54,311,972 bp from pter
54,312,048 bp from pter
77 bases
Minus strand

Genomic View for MIR1297 Gene

Genes around MIR1297 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1297 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1297 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1297 Gene

ORGUL Member Location for MIR1297 Gene

ORGUL Member Location for MIR1297 gene

Proteins for MIR1297 Gene

Post-translational modifications for MIR1297 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1297 Gene

Domains & Families for MIR1297 Gene

Gene Families for MIR1297 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1297: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1297 Gene

Function for MIR1297 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1297 Gene

Localization for MIR1297 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1297 Gene

Pathways & Interactions for MIR1297 Gene

SuperPathways for MIR1297 Gene

No Data Available

Interacting Proteins for MIR1297 Gene

Gene Ontology (GO) - Biological Process for MIR1297 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1297 Gene

Drugs & Compounds for MIR1297 Gene

No Compound Related Data Available

Transcripts for MIR1297 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1297 Gene

No ASD Table

Relevant External Links for MIR1297 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

No data available for mRNA/cDNA for MIR1297 Gene

Expression for MIR1297 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR1297 Gene

Orthologs for MIR1297 Gene

No data available for Orthologs and Evolution for MIR1297 Gene

Paralogs for MIR1297 Gene

No data available for Paralogs for MIR1297 Gene

Variants for MIR1297 Gene

Sequence variations from dbSNP and Humsavar for MIR1297 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
rs4351942 -- 54,311,740(+) TTGTC(A/C)AAGTT downstream-variant-500B
rs4884963 -- 54,311,609(+) AGTCA(C/T)TGAGT downstream-variant-500B
rs9527191 -- 54,313,738(+) ccata(C/T)gggga upstream-variant-2KB
rs9536676 -- 54,312,337(+) GCTTA(A/G)GTCAA upstream-variant-2KB
rs12583110 -- 54,312,977(+) CTGCG(C/G)TCCAG upstream-variant-2KB

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for MIR1297 Gene

Disorders for MIR1297 Gene

Relevant External Links for MIR1297

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR1297 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1297 Gene

Publications for MIR1297 Gene

  1. MicroRNA-1297 regulates hepatocellular carcinoma cell proliferation and apoptosis by targeting EZH2. (PMID: 26191190) Liu F. … Wang S. (Int J Clin Exp Pathol 2015) 3 67
  2. MiR-1297 regulates the growth, migration and invasion of colorectal cancer cells by targeting cyclo-oxygenase-2. (PMID: 25422199) Chen P. … Guo W. (Asian Pac. J. Cancer Prev. 2014) 3
  3. miR-1297 mediates PTEN expression and contributes to cell progression in LSCC. (PMID: 22995297) Li X. … Wang X. (Biochem. Biophys. Res. Commun. 2012) 3
  4. miR-511 and miR-1297 inhibit human lung adenocarcinoma cell proliferation by targeting oncogene TRIB2. (PMID: 23071539) Zhang C. … Xie S.Y. (PLoS ONE 2012) 3
  5. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3

Products for MIR1297 Gene

Sources for MIR1297 Gene