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Aliases for MIR1297 Gene

Subcategory (RNA class) for MIR1297 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1297 Gene

  • MicroRNA 1297 2 3 5
  • Hsa-Mir-1297 3
  • Mir-1297 3
  • MIRN1297 3

External Ids for MIR1297 Gene

Previous HGNC Symbols for MIR1297 Gene

  • MIRN1297

Previous GeneCards Identifiers for MIR1297 Gene

  • GC00U922917
  • GC13M053784
  • GC13M054886

Summaries for MIR1297 Gene

Entrez Gene Summary for MIR1297 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1297 Gene

MIR1297 (MicroRNA 1297) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1297 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1297 Gene

Genomics for MIR1297 Gene

Regulatory Elements for MIR1297 Gene

Enhancers for MIR1297 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH13H054266 0.6 ENCODE dbSUPER 0.3 +44.6 44624 1 SPI1 MIR1297 LINC00458
GH13H054268 0.5 Ensembl ENCODE 0.3 +43.2 43152 0 MIR1297 LINC00458
GH13H054270 0.4 dbSUPER 0.3 +40.3 40328 2 PAF1 MIR1297 LINC00458
GH13H054355 0.4 ENCODE 0.3 -44.7 -44701 3 POU5F1 CTBP2 MIR1297 RPL13AP25
GH13H054272 0.4 dbSUPER 0.3 +38.5 38542 1 PAF1 MIR1297 LINC00458
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1297 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1297 Gene

Chromosome:
13
Start:
54,311,972 bp from pter
End:
54,312,048 bp from pter
Size:
77 bases
Orientation:
Minus strand

Genomic View for MIR1297 Gene

Genes around MIR1297 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1297 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1297 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1297 Gene

ORGUL Member Location for MIR1297 Gene

ORGUL Member Location for MIR1297 gene

Proteins for MIR1297 Gene

Post-translational modifications for MIR1297 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1297 Gene

Domains & Families for MIR1297 Gene

Gene Families for MIR1297 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1297: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1297 Gene

Function for MIR1297 Gene

Phenotypes From GWAS Catalog for MIR1297 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR1297
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1297 Gene

Localization for MIR1297 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1297 Gene

Pathways & Interactions for MIR1297 Gene

SuperPathways for MIR1297 Gene

No Data Available

Interacting Proteins for MIR1297 Gene

Gene Ontology (GO) - Biological Process for MIR1297 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1297 Gene

Drugs & Compounds for MIR1297 Gene

No Compound Related Data Available

Transcripts for MIR1297 Gene

mRNA/cDNA for MIR1297 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR1297
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1297 Gene

No ASD Table

Relevant External Links for MIR1297 Gene

GeneLoc Exon Structure for
MIR1297
ECgene alternative splicing isoforms for
MIR1297

Expression for MIR1297 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1297 Gene:

MIR1297
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1297 Gene

Orthologs for MIR1297 Gene

Evolution for MIR1297 Gene

ENSEMBL:
Gene Tree for MIR1297 (if available)
TreeFam:
Gene Tree for MIR1297 (if available)

No data available for Orthologs for MIR1297 Gene

Paralogs for MIR1297 Gene

No data available for Paralogs for MIR1297 Gene

Variants for MIR1297 Gene

Sequence variations from dbSNP and Humsavar for MIR1297 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
rs1000968381 -- 54,313,765(+) CTCCC(A/C)TCCTG upstream-variant-2KB
rs1001643560 -- 54,312,161(+) ATGAT(A/G)CATTA upstream-variant-2KB
rs1002134487 -- 54,314,035(+) TGGGG(A/G/T)CGTGT upstream-variant-2KB
rs1004601619 -- 54,313,075(+) GTGGA(C/G)GGAAA upstream-variant-2KB
rs1004676094 -- 54,312,884(+) AAATG(A/G)TTAGA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1297 Gene

Variant ID Type Subtype PubMed ID
esv3892347 CNV gain 25118596

Relevant External Links for MIR1297 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1297

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1297 Gene

Disorders for MIR1297 Gene

Relevant External Links for MIR1297

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1297

No disorders were found for MIR1297 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1297 Gene

Publications for MIR1297 Gene

  1. Serum miR-1297: a promising diagnostic biomarker in esophageal squamous cell carcinoma. (PMID: 27152453) Wang C … Cheng Y (Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2016) 3 60
  2. MicroRNA-1297 inhibits prostate cancer cell proliferation and invasion by targeting the AEG-1/Wnt signaling pathway. (PMID: 27746178) Liang X … Li Z (Biochemical and biophysical research communications 2016) 3 60
  3. MiR-1297 promotes apoptosis and inhibits the proliferation and invasion of hepatocellular carcinoma cells by targeting HMGA2. (PMID: 26398017) Liu Y … Jiang X (International journal of molecular medicine 2015) 3 60
  4. MicroRNA-1297 regulates hepatocellular carcinoma cell proliferation and apoptosis by targeting EZH2. (PMID: 26191190) Liu F … Wang S (International journal of clinical and experimental pathology 2015) 3 60
  5. miRNA-1297 induces cell proliferation by targeting phosphatase and tensin homolog in testicular germ cell tumor cells. (PMID: 25124605) Yang NQ … Wang GM (Asian Pacific journal of cancer prevention : APJCP 2014) 3 60

Products for MIR1297 Gene

Sources for MIR1297 Gene

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