Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR1297 Gene

Subcategory (RNA class) for MIR1297 Gene

miRNA

Quality Score for this RNA gene is

7

Aliases for MIR1297 Gene

  • MicroRNA 1297 2 3
  • Hsa-Mir-1297 3
  • MIRN1297 3

External Ids for MIR1297 Gene

Previous HGNC Symbols for MIR1297 Gene

  • MIRN1297

Previous GeneCards Identifiers for MIR1297 Gene

  • GC00U922917
  • GC13M053784
  • GC13M054886

Summaries for MIR1297 Gene

Entrez Gene Summary for MIR1297 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1297 Gene

MIR1297 (MicroRNA 1297) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1297 Gene

Genomics for MIR1297 Gene

Genomic Location for MIR1297 Gene

Start:
54,311,972 bp from pter
End:
54,312,048 bp from pter
Size:
77 bases
Orientation:
Minus strand

Genomic View for MIR1297 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR1297 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1297 Gene

ORGUL Member Location for MIR1297 Gene

ORGUL Member Location for MIR1297 gene

No data available for Regulatory Elements for MIR1297 Gene

Proteins for MIR1297 Gene

Post-translational modifications for MIR1297 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1297 Gene

Domains for MIR1297 Gene

Gene Families for MIR1297 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1297: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1297 Gene

Function for MIR1297 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR1297 Gene

Localization for MIR1297 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1297 Gene

Pathways for MIR1297 Gene

SuperPathways for MIR1297 Gene

No Data Available

Interacting Proteins for MIR1297 Gene

Gene Ontology (GO) - Biological Process for MIR1297 Gene

None

No data available for Pathways by source for MIR1297 Gene

Transcripts for MIR1297 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1297 Gene

No ASD Table

Relevant External Links for MIR1297 Gene

GeneLoc Exon Structure for
MIR1297
ECgene alternative splicing isoforms for
MIR1297

No data available for mRNA/cDNA for MIR1297 Gene

Expression for MIR1297 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR1297 Gene

Orthologs for MIR1297 Gene

No data available for Orthologs and Evolution for MIR1297 Gene

Paralogs for MIR1297 Gene

No data available for Paralogs for MIR1297 Gene

Variants for MIR1297 Gene

Sequence variations from dbSNP and Humsavar for MIR1297 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
rs4351942 -- 54,311,740(+) TTGTC(A/C)AAGTT downstream-variant-500B
rs4884963 -- 54,311,609(+) AGTCA(C/T)TGAGT downstream-variant-500B
rs9527191 -- 54,313,738(+) ccata(C/T)gggga upstream-variant-2KB
rs9536676 -- 54,312,337(+) GCTTA(A/G)GTCAA upstream-variant-2KB
rs10162244 -- 54,311,970(+) TAGAA(C/G)TGTTT downstream-variant-500B

Relevant External Links for MIR1297 Gene

HapMap Linkage Disequilibrium report
MIR1297

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MIR1297 Gene

Disorders for MIR1297 Gene

No disorders were found for MIR1297 Gene.

No data available for UniProtKB/Swiss-Prot for MIR1297 Gene

Publications for MIR1297 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3
  3. miR-1297 mediates PTEN expression and contributes to cell progression in LSCC. (PMID: 22995297) Li X. … Wang X. (Biochem. Biophys. Res. Commun. 2012) 3
  4. miR-511 and miR-1297 inhibit human lung adenocarcinoma cell proliferation by targeting oncogene TRIB2. (PMID: 23071539) Zhang C. … Xie S.Y. (PLoS ONE 2012) 3

Products for MIR1297 Gene

Sources for MIR1297 Gene

Back to Top

Content