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Aliases for MIR1297 Gene

Subcategory (RNA class) for MIR1297 Gene


Quality Score for this RNA gene is


Aliases for MIR1297 Gene

  • MicroRNA 1297 2 3 5
  • Hsa-Mir-1297 3
  • Mir-1297 3
  • MIRN1297 3

External Ids for MIR1297 Gene

Previous HGNC Symbols for MIR1297 Gene

  • MIRN1297

Previous GeneCards Identifiers for MIR1297 Gene

  • GC00U922917
  • GC13M053784
  • GC13M054886

Summaries for MIR1297 Gene

Entrez Gene Summary for MIR1297 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1297 Gene

MIR1297 (MicroRNA 1297) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1297 Gene

Genomics for MIR1297 Gene

Regulatory Elements for MIR1297 Gene

Enhancers for MIR1297 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH13G054302 0.5 ENCODE 0.4 +10.8 10768 0.2 CTCF POU5F1 RAD21 MIR1297 LINC00458
GH13G054266 0.6 ENCODE dbSUPER 0.3 +44.6 44624 1.7 SPI1 MIR1297 LINC00458
GH13G054270 0.6 dbSUPER 0.3 +40.3 40328 2.1 CTCF PAF1 SMC3 EP300 ATF2 RAD21 MIR1297 LINC00458
GH13G054301 0.4 ENCODE 0.4 +10.4 10424 0.4 CTCF RAD21 MIR1297 LINC00458
GH13G054268 0.5 Ensembl ENCODE 0.3 +43.2 43152 1.0 MIR1297 LINC00458
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1297 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1297 Gene

54,311,972 bp from pter
54,312,048 bp from pter
77 bases
Minus strand

Genomic View for MIR1297 Gene

Genes around MIR1297 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1297 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1297 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1297 Gene

ORGUL Member Location for MIR1297 Gene

ORGUL Member Location for MIR1297 gene

Proteins for MIR1297 Gene

Post-translational modifications for MIR1297 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1297 Gene

Domains & Families for MIR1297 Gene

Gene Families for MIR1297 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1297: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1297 Gene

Function for MIR1297 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1297 Gene

Localization for MIR1297 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1297 Gene

Pathways & Interactions for MIR1297 Gene

SuperPathways for MIR1297 Gene

No Data Available

Interacting Proteins for MIR1297 Gene

Gene Ontology (GO) - Biological Process for MIR1297 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1297 Gene

Drugs & Compounds for MIR1297 Gene

No Compound Related Data Available

Transcripts for MIR1297 Gene

mRNA/cDNA for MIR1297 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1297 Gene

No ASD Table

Relevant External Links for MIR1297 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1297 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1297 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1297 Gene

Orthologs for MIR1297 Gene

Evolution for MIR1297 Gene

Gene Tree for MIR1297 (if available)
Gene Tree for MIR1297 (if available)

No data available for Orthologs for MIR1297 Gene

Paralogs for MIR1297 Gene

No data available for Paralogs for MIR1297 Gene

Variants for MIR1297 Gene

Sequence variations from dbSNP and Humsavar for MIR1297 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
rs1000968381 -- 54,313,765(+) CTCCC(A/C)TCCTG upstream-variant-2KB
rs1001643560 -- 54,312,161(+) ATGAT(A/G)CATTA upstream-variant-2KB
rs1002134487 -- 54,314,035(+) TGGGG(A/G/T)CGTGT upstream-variant-2KB
rs1004601619 -- 54,313,075(+) GTGGA(C/G)GGAAA upstream-variant-2KB
rs1004676094 -- 54,312,884(+) AAATG(A/G)TTAGA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1297 Gene

Variant ID Type Subtype PubMed ID
esv3892347 CNV gain 25118596

Relevant External Links for MIR1297 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1297 Gene

Disorders for MIR1297 Gene

Relevant External Links for MIR1297

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR1297 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1297 Gene

Publications for MIR1297 Gene

  1. Serum miR-1297: a promising diagnostic biomarker in esophageal squamous cell carcinoma. (PMID: 27152453) Wang C. … Cheng Y. (Biomarkers 2016) 3 64
  2. MicroRNA-1297 regulates hepatocellular carcinoma cell proliferation and apoptosis by targeting EZH2. (PMID: 26191190) Liu F. … Wang S. (Int J Clin Exp Pathol 2015) 3 64
  3. MiR-1297 promotes apoptosis and inhibits the proliferation and invasion of hepatocellular carcinoma cells by targeting HMGA2. (PMID: 26398017) Liu Y. … Jiang X. (Int. J. Mol. Med. 2015) 3 64
  4. miRNA-1297 induces cell proliferation by targeting phosphatase and tensin homolog in testicular germ cell tumor cells. (PMID: 25124605) Yang N.Q. … Wang G.M. (Asian Pac. J. Cancer Prev. 2014) 3 64
  5. MiR-1297 regulates the growth, migration and invasion of colorectal cancer cells by targeting cyclo-oxygenase-2. (PMID: 25422199) Chen P. … Guo W. (Asian Pac. J. Cancer Prev. 2014) 3 64

Products for MIR1297 Gene

Sources for MIR1297 Gene

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