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Aliases for MIR1295B Gene

Subcategory (RNA class) for MIR1295B Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1295B Gene

  • MicroRNA 1295b 2 3 5
  • Hsa-Mir-1295b 3

External Ids for MIR1295B Gene

Previous GeneCards Identifiers for MIR1295B Gene

  • GC01U903329

Summaries for MIR1295B Gene

Entrez Gene Summary for MIR1295B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1295B Gene

MIR1295B (MicroRNA 1295b) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1295B Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1295B Gene

Genomics for MIR1295B Gene

Genomic Location for MIR1295B Gene

Chromosome:
1
Start:
171,101,739 bp from pter
End:
171,101,798 bp from pter
Size:
60 bases
Orientation:
Plus strand

Genomic View for MIR1295B Gene

Genes around MIR1295B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1295B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1295B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1295B Gene

No data available for Regulatory Elements for MIR1295B Gene

Proteins for MIR1295B Gene

Post-translational modifications for MIR1295B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1295B Gene

Domains & Families for MIR1295B Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1295B Gene

Function for MIR1295B Gene

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for MIR1295B
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1295B Gene

Localization for MIR1295B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1295B Gene

Pathways & Interactions for MIR1295B Gene

SuperPathways for MIR1295B Gene

No Data Available

Interacting Proteins for MIR1295B Gene

Gene Ontology (GO) - Biological Process for MIR1295B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1295B Gene

Drugs & Compounds for MIR1295B Gene

No Compound Related Data Available

Transcripts for MIR1295B Gene

mRNA/cDNA for MIR1295B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for MIR1295B
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1295B Gene

No ASD Table

Relevant External Links for MIR1295B Gene

GeneLoc Exon Structure for
MIR1295B
ECgene alternative splicing isoforms for
MIR1295B

Expression for MIR1295B Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1295B Gene:

MIR1295B
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1295B Gene

Orthologs for MIR1295B Gene

Evolution for MIR1295B Gene

ENSEMBL:
Gene Tree for MIR1295B (if available)
TreeFam:
Gene Tree for MIR1295B (if available)

No data available for Orthologs for MIR1295B Gene

Paralogs for MIR1295B Gene

No data available for Paralogs for MIR1295B Gene

Variants for MIR1295B Gene

Sequence variations from dbSNP and Humsavar for MIR1295B Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000858689 -- 171,100,576(+) TCCAT(A/G)TCCAG intron-variant, upstream-variant-2KB
rs1001287866 -- 171,100,265(+) GCATA(A/G)GTTGA intron-variant, upstream-variant-2KB
rs1001591579 -- 171,102,293(+) CTCAG(C/T)ACTTT intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1003107481 -- 171,102,046(+) CCACA(A/T)GCCTA intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1003358132 -- 171,100,849(+) TGTTA(C/T)CTTAC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1295B Gene

Variant ID Type Subtype PubMed ID
esv28731 CNV gain+loss 19812545

Relevant External Links for MIR1295B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1295B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1295B Gene

Disorders for MIR1295B Gene

Relevant External Links for MIR1295B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1295B

No disorders were found for MIR1295B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1295B Gene

Publications for MIR1295B Gene

  1. Decreased expression of fecal miR-4478 and miR-1295b-3p in early-stage colorectal cancer. (PMID: 25519020) Ghanbari R … Knuutila S (Cancer biomarkers : section A of Disease markers 2015) 3 60
  2. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3 60
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR1295B Gene

Sources for MIR1295B Gene

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