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Aliases for MIR1293 Gene

Subcategory (RNA class) for MIR1293 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1293 Gene

  • MicroRNA 1293 2 3 5
  • Hsa-Mir-1293 3
  • Mir-1293 3
  • MIRN1293 3

External Ids for MIR1293 Gene

Previous HGNC Symbols for MIR1293 Gene

  • MIRN1293

Previous GeneCards Identifiers for MIR1293 Gene

  • GC00U923124
  • GC12M048915
  • GC12M050627

Summaries for MIR1293 Gene

Entrez Gene Summary for MIR1293 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1293 Gene

MIR1293 (MicroRNA 1293) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR1293 include Renal Cell Carcinoma, Papillary, 1.

Additional gene information for MIR1293 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1293 Gene

Genomics for MIR1293 Gene

GeneHancer (GH) Regulatory Elements for MIR1293 Gene

Promoters and enhancers for MIR1293 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12I050234 Enhancer 0.7 ENCODE 550.8 -0.4 -412 1 CTCF MXI1 KLF17 MAX RAD21 FOSL1 ZNF121 POLR3A SMC3 FOSL2 MIR1293 CERS5 SPATS2 ENSG00000257298 RNU6-1093P LIMA1
GH12I050232 Enhancer 0.6 ENCODE 550.8 +1.3 1331 0.6 MEIS2 ZNF189 GFI1B FEZF1 ZIC2 SREBF1 GATA3 PRDM6 POLR2A ZNF341 MIR1293 ENSG00000257256 LIMA1
GH12I050217 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 0.4 +13.0 13047 8 HNRNPUL1 PKNOX1 CLOCK SMAD1 ARNT NEUROD1 SIN3A FEZF1 ZNF2 IRF4 ENSG00000257256 LIMA1 SMARCD1 CERS5 SPATS2 ATF1 LOC101927267 PRPF40B GC12M050135 ENSG00000257531
GH12I050246 Promoter/Enhancer 2 EPDnew Ensembl ENCODE dbSUPER 0.4 -17.2 -17238 10.5 HDGF PKNOX1 SMAD1 FOXA2 ARNT NEUROD1 FEZF1 ZNF2 IRF4 ZNF143 LIMA1 ENSG00000257298 PRPF40B PRPH LOC100422296 SMARCD1 CERS5 SPATS2 SLC11A2 ENSG00000257964
GH12I050239 Enhancer 1.3 Ensembl ENCODE dbSUPER 0.4 -7.7 -7666 5 PKNOX1 FOXA2 ZNF133 TCF12 FOS SP5 NFYC REST PPARG NFIL3 CERS5 LIMA1 MIR1293 RNU6-1093P
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1293 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1293 Gene

Genomic Locations for MIR1293 Gene
chr12:50,234,142-50,234,212
(GRCh38/hg38)
Size:
71 bases
Orientation:
Minus strand
chr12:50,627,925-50,627,995
(GRCh37/hg19)

Genomic View for MIR1293 Gene

Genes around MIR1293 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1293 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1293 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1293 Gene

ORGUL Member Location for MIR1293 Gene

ORGUL Member Location for MIR1293 gene

Proteins for MIR1293 Gene

Post-translational modifications for MIR1293 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1293 Gene

Domains & Families for MIR1293 Gene

Gene Families for MIR1293 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1293: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1293 Gene

Function for MIR1293 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1293 Gene

Localization for MIR1293 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1293 Gene

Pathways & Interactions for MIR1293 Gene

SuperPathways for MIR1293 Gene

No Data Available

Interacting Proteins for MIR1293 Gene

Gene Ontology (GO) - Biological Process for MIR1293 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1293 Gene

Drugs & Compounds for MIR1293 Gene

No Compound Related Data Available

Transcripts for MIR1293 Gene

mRNA/cDNA for MIR1293 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1293 Gene

No ASD Table

Relevant External Links for MIR1293 Gene

GeneLoc Exon Structure for
MIR1293
ECgene alternative splicing isoforms for
MIR1293

Expression for MIR1293 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1293 Gene:

MIR1293
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1293 Gene

Orthologs for MIR1293 Gene

Evolution for MIR1293 Gene

ENSEMBL:
Gene Tree for MIR1293 (if available)
TreeFam:
Gene Tree for MIR1293 (if available)

No data available for Orthologs for MIR1293 Gene

Paralogs for MIR1293 Gene

No data available for Paralogs for MIR1293 Gene

Variants for MIR1293 Gene

Sequence variations from dbSNP and Humsavar for MIR1293 Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs1001559131 -- 50,235,058(-) A/C upstream_transcript_variant
rs1001616303 -- 50,235,394(-) T/A upstream_transcript_variant
rs1001675215 -- 50,234,850(-) C/T upstream_transcript_variant
rs1002013873 -- 50,236,201(-) T/C upstream_transcript_variant
rs1004888196 -- 50,235,249(-) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1293 Gene

Variant ID Type Subtype PubMed ID
esv2761738 CNV gain 21179565

Additional Variant Information for MIR1293 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1293

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1293 Gene

Disorders for MIR1293 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR1293 Gene - From: DISEASES

Disorder Aliases PubMed IDs
renal cell carcinoma, papillary, 1
  • rccp1
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR1293

genes like me logo Genes that share disorders with MIR1293: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR1293 Gene

Publications for MIR1293 Gene

  1. hsa-mir-3199-2 and hsa-mir-1293 as Novel Prognostic Biomarkers of Papillary Renal Cell Carcinoma by COX Ratio Risk Regression Model Screening. (PMID: 28338236) Luo W … Wang XX (Journal of cellular biochemistry 2017) 3 58
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  3. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR1293 Gene

Sources for MIR1293 Gene

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