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Aliases for MIR1291 Gene

Subcategory (RNA class) for MIR1291 Gene

miRNA

Quality Score for this RNA gene is

7

Aliases for MIR1291 Gene

  • MicroRNA 1291 2 3
  • Hsa-Mir-1291 3
  • MIRN1291 3
  • SNORA34 6
  • ACA34, 6

External Ids for MIR1291 Gene

Previous HGNC Symbols for MIR1291 Gene

  • MIRN1291

Previous GeneCards Identifiers for MIR1291 Gene

  • GC00U923104
  • GC12M047341
  • GC12M049049
  • GC12M049052
  • GC12M049058
  • GC12M049066
  • GC12U901807
  • GC12M049089

Summaries for MIR1291 Gene

Entrez Gene Summary for MIR1291 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1291 Gene

MIR1291 (MicroRNA 1291) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1291 Gene

Genomics for MIR1291 Gene

Genomic Location for MIR1291 Gene

Start:
48,654,444 bp from pter
End:
48,654,530 bp from pter
Size:
87 bases
Orientation:
Minus strand

Genomic View for MIR1291 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR1291 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1291 Gene

ORGUL Member Location for MIR1291 Gene

ORGUL Member Location for MIR1291 gene

No data available for Regulatory Elements for MIR1291 Gene

Proteins for MIR1291 Gene

Post-translational modifications for MIR1291 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1291 Gene

Domains for MIR1291 Gene

Gene Families for MIR1291 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1291: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1291 Gene

Function for MIR1291 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR1291 Gene

Localization for MIR1291 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1291 Gene

Pathways for MIR1291 Gene

SuperPathways for MIR1291 Gene

No Data Available

Interacting Proteins for MIR1291 Gene

Gene Ontology (GO) - Biological Process for MIR1291 Gene

None

No data available for Pathways by source for MIR1291 Gene

Transcripts for MIR1291 Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MIR1291

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1291 Gene

No ASD Table

Relevant External Links for MIR1291 Gene

GeneLoc Exon Structure for
MIR1291
ECgene alternative splicing isoforms for
MIR1291

No data available for mRNA/cDNA for MIR1291 Gene

Expression for MIR1291 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR1291 Gene

Orthologs for MIR1291 Gene

No data available for Orthologs and Evolution for MIR1291 Gene

Paralogs for MIR1291 Gene

No data available for Paralogs for MIR1291 Gene

Variants for MIR1291 Gene

Relevant External Links for MIR1291 Gene

HapMap Linkage Disequilibrium report
MIR1291

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR1291 Gene

Disorders for MIR1291 Gene

No disorders were found for MIR1291 Gene.

No data available for UniProtKB/Swiss-Prot for MIR1291 Gene

Publications for MIR1291 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3
  3. Human miRNA precursors with box H/ACA snoRNA features. (PMID: 19763159) Scott M.S. … Barton G.J. (PLoS Comput. Biol. 2009) 3
  4. MicroRNA-1291-mediated silencing of IRE1I+ enhances Glypican-3 expression. (PMID: 23598528) Maurel M. … Grosset C.F. (RNA 2013) 3
  5. Small nucleolar RNA-derived microRNA hsa-miR-1291 modulates cellular drug disposition through direct targeting of ABC transporter ABCC1. (PMID: 23686318) Pan Y.Z. … Yu A.M. (Drug Metab. Dispos. 2013) 3

Products for MIR1291 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR1291
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR1291
    • Block miRNA regulation of MIR1291 using miScript Target Protectors

    Sources for MIR1291 Gene

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