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Aliases for MIR1291 Gene

Subcategory (RNA class) for MIR1291 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1291 Gene

  • MicroRNA 1291 2 3 5
  • Hsa-Mir-1291 3
  • Mir-1291 3
  • MIRN1291 3

External Ids for MIR1291 Gene

Previous HGNC Symbols for MIR1291 Gene

  • MIRN1291

Previous GeneCards Identifiers for MIR1291 Gene

  • GC00U923104
  • GC12M047341
  • GC12M049049
  • GC12M049052
  • GC12M049058
  • GC12M049066
  • GC12U901807
  • GC12M049089

Summaries for MIR1291 Gene

Entrez Gene Summary for MIR1291 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1291 Gene

MIR1291 (MicroRNA 1291) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1291 Gene

Genomics for MIR1291 Gene

Genomic Location for MIR1291 Gene

Chromosome:
12
Start:
48,654,444 bp from pter
End:
48,654,530 bp from pter
Size:
87 bases
Orientation:
Minus strand

Genomic View for MIR1291 Gene

Genes around MIR1291 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1291 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1291 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1291 Gene

ORGUL Member Location for MIR1291 Gene

ORGUL Member Location for MIR1291 gene

No data available for Regulatory Elements for MIR1291 Gene

Proteins for MIR1291 Gene

Post-translational modifications for MIR1291 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1291 Gene

Domains & Families for MIR1291 Gene

Gene Families for MIR1291 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1291: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1291 Gene

Function for MIR1291 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1291 Gene

Localization for MIR1291 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1291 Gene

Pathways & Interactions for MIR1291 Gene

SuperPathways for MIR1291 Gene

No Data Available

Interacting Proteins for MIR1291 Gene

Gene Ontology (GO) - Biological Process for MIR1291 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1291 Gene

Transcripts for MIR1291 Gene

mRNA/cDNA for MIR1291 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1291 Gene

No ASD Table

Relevant External Links for MIR1291 Gene

GeneLoc Exon Structure for
MIR1291
ECgene alternative splicing isoforms for
MIR1291

Expression for MIR1291 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1291 Gene:

MIR1291
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1291 Gene

Orthologs for MIR1291 Gene

Evolution for MIR1291 Gene

ENSEMBL:
Gene Tree for MIR1291 (if available)
TreeFam:
Gene Tree for MIR1291 (if available)

No data available for Orthologs for MIR1291 Gene

Paralogs for MIR1291 Gene

No data available for Paralogs for MIR1291 Gene

Variants for MIR1291 Gene

Sequence variations from dbSNP and Humsavar for MIR1291 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs1001115628 -- 48,654,762(+) AGAGT(A/G)GGGCA intron-variant, upstream-variant-2KB
rs1001146712 -- 48,654,427(+) TCCCA(C/G)AACAG intron-variant, nc-transcript-variant, downstream-variant-500B
rs1001624913 -- 48,656,476(+) CACCA(C/T)GTTAG intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1002081898 -- 48,656,143(+) AAGCT(A/C)CAACA intron-variant, upstream-variant-2KB
rs1002155624 -- 48,655,853(+) GCCAG(A/G)AATTC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1291 Gene

Variant ID Type Subtype PubMed ID
dgv1496n100 CNV gain 25217958

Relevant External Links for MIR1291 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1291

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1291 Gene

Disorders for MIR1291 Gene

Relevant External Links for MIR1291

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1291

No disorders were found for MIR1291 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1291 Gene

Publications for MIR1291 Gene

  1. miR-1291 targets mucin 1 inhibiting cell proliferation and invasion to promote cell apoptosis in esophageal squamous cell carcinoma. (PMID: 26324125) Luo H. … Wang F. (Oncol. Rep. 2015) 3 64
  2. Clinical impact of circulating miR-133, miR-1291 and miR-663b in plasma of patients with acute myocardial infarction. (PMID: 24885383) Peng L. … Zhen-wen H. (Diagn Pathol 2014) 3 64
  3. N-methylnicotinamide and nicotinamide N-methyltransferase are associated with microRNA-1291-altered pancreatic carcinoma cell metabolome and suppressed tumorigenesis. (PMID: 25115443) Bi H.C. … Yu A.M. (Carcinogenesis 2014) 3 64
  4. Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles. (PMID: 25187353) Goldstein J.I. … Sullivan P.F. (Nat Commun 2014) 3 64
  5. MicroRNA-1291-mediated silencing of IRE1I+ enhances Glypican-3 expression. (PMID: 23598528) Maurel M. … Grosset C.F. (RNA 2013) 3 64

Products for MIR1291 Gene

Sources for MIR1291 Gene

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