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Aliases for MIR1290 Gene

Subcategory (RNA class) for MIR1290 Gene


Quality Score for this RNA gene is


Aliases for MIR1290 Gene

  • MicroRNA 1290 2 3 5
  • Hsa-Mir-1290 3
  • MIRN1290 3

External Ids for MIR1290 Gene

Previous HGNC Symbols for MIR1290 Gene

  • MIRN1290

Previous GeneCards Identifiers for MIR1290 Gene

  • GC00U923065
  • GC01M019097
  • GC01M019223

Summaries for MIR1290 Gene

Entrez Gene Summary for MIR1290 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1290 Gene

MIR1290 (MicroRNA 1290) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1290 Gene

Genomics for MIR1290 Gene

Regulatory Elements for MIR1290 Gene

Enhancers for MIR1290 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F018972 0.7 Ensembl ENCODE 11.3 -75.9 -75853 1.2 CTCF CREB3L1 ZMYM3 RAD21 GTF3C2 GATA3 GATA2 ZNF366 SCRT2 SMC3 ALDH4A1 MIR1290 TAS1R2 EMC1 AKR7A3 IFFO2 GC01P019006
GH01F019045 1 Ensembl ENCODE 11.1 -148.5 -148515 0.9 ELF3 RAD21 RARA YY1 SCRT2 THAP11 HMG20B PPARG NR2F2 KLF16 ALDH4A1 MIR1290 EMC1 LOC105376815 GC01P019027
GH01F018989 0.4 ENCODE 10.4 -91.9 -91894 0.1 ELF3 HDAC1 MLX ARID4B NFXL1 ZBTB40 RAD21 RARA GATA4 ZNF143 IFFO2 ALDH4A1 MIR1290 GC01P019006
GH01F018893 0.7 ENCODE 0.8 +3.2 3236 0.0 MIR1290 MIR4695
GH01F018894 0.5 Ensembl 0.8 +2.4 2448 0.2 TFAP4 TFE3 SAP130 NR2F1 NR2F2 RARA ZNF121 PBX2 SMAD4 BCL6 MIR1290 MIR4695
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR1290 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1290 Gene

18,897,071 bp from pter
18,897,148 bp from pter
78 bases
Minus strand

Genomic View for MIR1290 Gene

Genes around MIR1290 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1290 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1290 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1290 Gene

Proteins for MIR1290 Gene

Post-translational modifications for MIR1290 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1290 Gene

Domains & Families for MIR1290 Gene

Gene Families for MIR1290 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1290: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1290 Gene

Function for MIR1290 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1290 Gene

Localization for MIR1290 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1290 Gene

Pathways & Interactions for MIR1290 Gene

SuperPathways for MIR1290 Gene

No Data Available

Interacting Proteins for MIR1290 Gene

Gene Ontology (GO) - Biological Process for MIR1290 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1290 Gene

Transcripts for MIR1290 Gene

mRNA/cDNA for MIR1290 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1290 Gene

No ASD Table

Relevant External Links for MIR1290 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1290 Gene

mRNA expression in normal human tissues for MIR1290 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1290 Gene:

genes like me logo Genes that share expression patterns with MIR1290: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1290 Gene

Orthologs for MIR1290 Gene

Evolution for MIR1290 Gene

Gene Tree for MIR1290 (if available)
Gene Tree for MIR1290 (if available)

No data available for Orthologs for MIR1290 Gene

Paralogs for MIR1290 Gene

No data available for Paralogs for MIR1290 Gene

Variants for MIR1290 Gene

Sequence variations from dbSNP and Humsavar for MIR1290 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs113388673 -- 18,897,163(+) GCTCA(C/T)TGGAG intron-variant, upstream-variant-2KB
rs113684865 -- 18,897,559(+) AACCC(A/C)AAAAA intron-variant, upstream-variant-2KB
rs116758419 -- 18,899,046(+) GAGGA(C/T)ACTGA intron-variant, upstream-variant-2KB
rs137857722 -- 18,897,839(+) AAAGC(C/T)GCCGC intron-variant, upstream-variant-2KB
rs140269017 -- 18,897,712(+) CCTTA(C/G)TCAGG intron-variant, upstream-variant-2KB

Relevant External Links for MIR1290 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR1290 Gene

Disorders for MIR1290 Gene

Relevant External Links for MIR1290

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR1290 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1290 Gene

Publications for MIR1290 Gene

  1. Hsa-miR-1246 and hsa-miR-1290 are associated with stemness and invasiveness of non-small cell lung cancer. (PMID: 26711929) Kim G. … Jeong H.C. (Lung Cancer 2016) 3 64
  2. Antagomir-1290 suppresses CD133a8_ cells in non-small cell lung cancer by targeting fyn-related Src family tyrosine kinase. (PMID: 25783528) Sun B. … Zuo P. (Tumour Biol. 2015) 3 64
  3. Global miRNA Expression Profiling Identifies miR-1290 as Novel Potential oncomiR in Laryngeal Carcinoma. (PMID: 26694163) Janiszewska J. … Jarmuz-Szymczak M. (PLoS ONE 2015) 3 64
  4. MicroRNA-1290 promotes esophageal squamous cell carcinoma cell proliferation and metastasis. (PMID: 25805931) Li M. … Shi R.H. (World J. Gastroenterol. 2015) 3 64
  5. Two cellular microRNAs, miR-196b and miR-1290, contribute to HIV-1 latency. (PMID: 26469550) Wang P. … Zhu H. (Virology 2015) 3 64

Products for MIR1290 Gene

Sources for MIR1290 Gene

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