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Aliases for MIR1290 Gene

Subcategory (RNA class) for MIR1290 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1290 Gene

  • MicroRNA 1290 2 3 5
  • Hsa-Mir-1290 3
  • MIRN1290 3

External Ids for MIR1290 Gene

Previous HGNC Symbols for MIR1290 Gene

  • MIRN1290

Previous GeneCards Identifiers for MIR1290 Gene

  • GC00U923065
  • GC01M019097
  • GC01M019223

Summaries for MIR1290 Gene

Entrez Gene Summary for MIR1290 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1290 Gene

MIR1290 (MicroRNA 1290) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1290 Gene

Genomics for MIR1290 Gene

Regulatory Elements for MIR1290 Gene

Enhancers for MIR1290 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR1290 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1290 Gene

Chromosome:
1
Start:
18,897,071 bp from pter
End:
18,897,148 bp from pter
Size:
78 bases
Orientation:
Minus strand

Genomic View for MIR1290 Gene

Genes around MIR1290 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1290 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1290 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1290 Gene

Proteins for MIR1290 Gene

Post-translational modifications for MIR1290 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1290 Gene

Domains & Families for MIR1290 Gene

Gene Families for MIR1290 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1290: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1290 Gene

Function for MIR1290 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1290 Gene

Localization for MIR1290 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1290 Gene

Pathways & Interactions for MIR1290 Gene

SuperPathways for MIR1290 Gene

No Data Available

Interacting Proteins for MIR1290 Gene

Gene Ontology (GO) - Biological Process for MIR1290 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1290 Gene

Drugs & Compounds for MIR1290 Gene

No Compound Related Data Available

Transcripts for MIR1290 Gene

mRNA/cDNA for MIR1290 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1290 Gene

No ASD Table

Relevant External Links for MIR1290 Gene

GeneLoc Exon Structure for
MIR1290
ECgene alternative splicing isoforms for
MIR1290

Expression for MIR1290 Gene

mRNA expression in normal human tissues for MIR1290 Gene

genes like me logo Genes that share expression patterns with MIR1290: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR1290 Gene

Orthologs for MIR1290 Gene

Evolution for MIR1290 Gene

ENSEMBL:
Gene Tree for MIR1290 (if available)
TreeFam:
Gene Tree for MIR1290 (if available)

No data available for Orthologs for MIR1290 Gene

Paralogs for MIR1290 Gene

No data available for Paralogs for MIR1290 Gene

Variants for MIR1290 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for MIR1290 Gene

Disorders for MIR1290 Gene

Relevant External Links for MIR1290

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1290

No disorders were found for MIR1290 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1290 Gene

Publications for MIR1290 Gene

  1. MiR-1290 promotes cancer progression by targeting nuclear factor I/X(NFIX) in esophageal squamous cell carcinoma (ESCC). (PMID: 26653554) Mao Y. … Li B. (Biomed. Pharmacother. 2015) 3 67
  2. Antagomir-1290 suppresses CD133a8_ cells in non-small cell lung cancer by targeting fyn-related Src family tyrosine kinase. (PMID: 25783528) Sun B. … Zuo P. (Tumour Biol. 2015) 3
  3. MicroRNA-1290 promotes esophageal squamous cell carcinoma cell proliferation and metastasis. (PMID: 25805931) Li M. … Shi R.H. (World J. Gastroenterol. 2015) 3
  4. The evolutionary young miR-1290 favors mitotic exit and differentiation of human neural progenitors through altering the cell cycle proteins. (PMID: 24407235) Yelamanchili S.V. … Fox H.S. (Cell Death Dis 2014) 3
  5. A three-microRNA signature predicts responses to platinum-based doublet chemotherapy in patients with lung adenocarcinoma. (PMID: 25142144) Saito M. … Kohno T. (Clin. Cancer Res. 2014) 3

Products for MIR1290 Gene

Sources for MIR1290 Gene

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