Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR129-2 Gene

Subcategory (RNA class) for MIR129-2 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR129-2 Gene

  • MicroRNA 129-2 2 3
  • Hsa-Mir-129-2 3
  • Mir-129-2 3
  • MIRN129-2 3
  • MIR-129b 3

External Ids for MIR129-2 Gene

ORGUL Members for MIR129-2 Gene

Previous Symbols for MIR129-2 Gene

  • MIRN129-2

Summaries for MIR129-2 Gene

Entrez Gene Summary for MIR129-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR129-2 Gene

MIR129-2 (MicroRNA 129-2) is a RNA Gene, and belongs to miRNA RNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR129-2 Gene

Genomics for MIR129-2 Gene

Genomic Location for MIR129-2 Gene

Start:
43,581,380 bp from pter
End:
43,581,487 bp from pter
Size:
108 bases
Orientation:
Plus strand

Genomic View for MIR129-2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR129-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR129-2 Gene

No data available for Regulatory Elements for MIR129-2 Gene

Proteins for MIR129-2 Gene

Post-translational modifications for MIR129-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR129-2 Gene

Domains for MIR129-2 Gene

Gene Families for MIR129-2 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR129-2: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR129-2 Gene

Function for MIR129-2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR129-2 Gene

Localization for MIR129-2 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR129-2 Gene

Pathways for MIR129-2 Gene

SuperPathways for MIR129-2 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR129-2: view

Pathways by source for MIR129-2 Gene

1 KEGG pathway for MIR129-2 Gene

Interacting Proteins for MIR129-2 Gene

Gene Ontology (GO) - Biological Process for MIR129-2 Gene

None

Transcripts for MIR129-2 Gene

mRNA/cDNA for MIR129-2 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR129-2 Gene

No ASD Table

Relevant External Links for MIR129-2 Gene

GeneLoc Exon Structure for
MIR129-2
ECgene alternative splicing isoforms for
MIR129-2

Expression for MIR129-2 Gene

mRNA expression in normal human tissues for MIR129-2 Gene

genes like me logo Genes that share expressions with MIR129-2: view

Orthologs for MIR129-2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR129-2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-129-2 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-129-2 37
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-129-2 37
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir129-2 37
  • 98 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-129a 37
  • 65 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii CR376745.1 37
  • 89 (a)
ManyToMany
dre-mir-129-1 37
  • 79 (a)
ManyToMany
dre-mir-129-2 37
  • 87 (a)
ManyToMany
Species with no ortholog for MIR129-2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR129-2 Gene

ENSEMBL:
Gene Tree for MIR129-2 (if available)
TreeFam:
Gene Tree for MIR129-2 (if available)

Paralogs for MIR129-2 Gene

No data available for Paralogs for MIR129-2 Gene

Variants for MIR129-2 Gene

Relevant External Links for MIR129-2 Gene

HapMap Linkage Disequilibrium report
MIR129-2

No data available for Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR129-2 Gene

Disorders for MIR129-2 Gene

No disorders were found for MIR129-2 Gene.

No data available for UniProtKB/Swiss-Prot for MIR129-2 Gene

Publications for MIR129-2 Gene

  1. Identification of tissue-specific microRNAs from mouse. (PMID: 12007417) Lagos-Quintana M. … Tuschl T. (Curr. Biol. 2002) 3
  2. New microRNAs from mouse and human. (PMID: 12554859) Lagos-Quintana M. … Tuschl T. (RNA 2003) 3
  3. Vertebrate microRNA genes. (PMID: 12624257) Lim L.P. … Bartel D.P. (Science 2003) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  5. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3

Products for MIR129-2 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR129-2
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR129-2
    • Block miRNA regulation of MIR129-2 using miScript Target Protectors

    Sources for MIR129-2 Gene

    Back to Top

    Content