Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR129-1 Gene

Subcategory (RNA class) for MIR129-1 Gene


Quality Score for this RNA gene is


Aliases for MIR129-1 Gene

  • MicroRNA 129-1 2 3
  • Hsa-Mir-129-1 3
  • Mir-129-1 3
  • MIRN129-1 3
  • MIR-129b 3

External Ids for MIR129-1 Gene

ORGUL Members for MIR129-1 Gene

Previous HGNC Symbols for MIR129-1 Gene

  • MIRN129-1

Previous GeneCards Identifiers for MIR129-1 Gene

  • GC07P127637
  • GC07P127847

Summaries for MIR129-1 Gene

Entrez Gene Summary for MIR129-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR129-1 Gene

MIR129-1 (MicroRNA 129-1) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR129-1 Gene

Genomics for MIR129-1 Gene

Genomic Location for MIR129-1 Gene

128,207,871 bp from pter
128,207,943 bp from pter
73 bases
Plus strand

Genomic View for MIR129-1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR129-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR129-1 Gene

No data available for Regulatory Elements for MIR129-1 Gene

Proteins for MIR129-1 Gene

Post-translational modifications for MIR129-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR129-1 Gene

Domains & Families for MIR129-1 Gene

Gene Families for MIR129-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR129-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR129-1 Gene

Function for MIR129-1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR129-1 Gene

Localization for MIR129-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR129-1 Gene

Pathways & Interactions for MIR129-1 Gene

SuperPathways for MIR129-1 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR129-1: view

Pathways by source for MIR129-1 Gene

1 KEGG pathway for MIR129-1 Gene

Interacting Proteins for MIR129-1 Gene

Gene Ontology (GO) - Biological Process for MIR129-1 Gene


No data available for SIGNOR curated interactions for MIR129-1 Gene

Drugs & Compounds for MIR129-1 Gene

No Compound Related Data Available

Transcripts for MIR129-1 Gene

mRNA/cDNA for MIR129-1 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR129-1 Gene

No ASD Table

Relevant External Links for MIR129-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR129-1 Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR129-1 Gene

Orthologs for MIR129-1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR129-1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-129-1 36
  • 86 (a)
(Canis familiaris)
Mammalia cfa-mir-129-1 36
  • 100 (a)
(Monodelphis domestica)
Mammalia mdo-mir-129 36
  • 93 (a)
(Mus musculus)
Mammalia Mir129-1 36
  • 95 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-129 36
  • 55 (a)
(Pan troglodytes)
Mammalia ptr-mir-129-1 36
  • 100 (a)
(Anolis carolinensis)
Reptilia aca-mir-129b 36
  • 68 (a)
(Danio rerio)
Actinopterygii BX927136.1 36
  • 55 (a)
Species with no ortholog for MIR129-1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR129-1 Gene

Gene Tree for MIR129-1 (if available)
Gene Tree for MIR129-1 (if available)

Paralogs for MIR129-1 Gene

No data available for Paralogs for MIR129-1 Gene

Variants for MIR129-1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR129-1 Gene

Variant ID Type Subtype PubMed ID
esv33413 CNV Gain 17666407

Relevant External Links for MIR129-1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR129-1 Gene

Disorders for MIR129-1 Gene

Relevant External Links for MIR129-1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR129-1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR129-1 Gene

Publications for MIR129-1 Gene

  1. miR-129 suppresses tumor cell growth and invasion by targeting PAK5 in hepatocellular carcinoma. (PMID: 26116538) Zhai J. … Wu D. (Biochem. Biophys. Res. Commun. 2015) 67
  2. miR-129-1-3p inhibits cell migration by targeting BDKRB2 in gastric cancer. (PMID: 25008064) Wang D. … Guo J. (Med. Oncol. 2014) 67
  3. MiR-129-5p is down-regulated and involved in the growth, apoptosis and migration of medullary thyroid carcinoma cells through targeting RET. (PMID: 24631532) Duan L. … Zhang G. (FEBS Lett. 2014) 67
  4. Methylation of miR-129-5p CpG island modulates multi-drug resistance in gastric cancer by targeting ABC transporters. (PMID: 25344911) Wu Q. … Fan D. (Oncotarget 2014) 67
  5. miR-129-1-3p promote BGC-823 cell proliferation by targeting PDCD2. (PMID: 25111461) Du Y. … Guo J. (Anat Rec (Hoboken) 2014) 67

Products for MIR129-1 Gene

Sources for MIR129-1 Gene

Back to Top