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Aliases for MIR1289-2 Gene

Subcategory (RNA class) for MIR1289-2 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1289-2 Gene

  • MicroRNA 1289-2 2 3 5
  • Hsa-Mir-1289-2 3
  • MIRN1289-2 3

External Ids for MIR1289-2 Gene

Previous HGNC Symbols for MIR1289-2 Gene

  • MIRN1289-2

Previous GeneCards Identifiers for MIR1289-2 Gene

  • GC00U923069
  • GC05M132792
  • GC05M132763

Summaries for MIR1289-2 Gene

Entrez Gene Summary for MIR1289-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1289-2 Gene

MIR1289-2 (MicroRNA 1289-2) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1289-2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1289-2 Gene

Genomics for MIR1289-2 Gene

Regulatory Elements for MIR1289-2 Gene

Enhancers for MIR1289-2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05H133244 1.5 FANTOM5 Ensembl ENCODE 9.7 +182.0 182048 3 PKNOX1 FOXA2 ATF1 ZFP64 GLIS2 ATF7 FOS RUNX3 JUNB REST MIR1289-2 SOWAHA ENSG00000249478 ENSG00000250244
GH05H133456 1 Ensembl ENCODE 12 -29.3 -29270 1 FOXA2 NFIB MAX CEBPG RAD21 YY1 GATA3 RCOR1 TFE3 ZNF687 MIR1289-2 ENSG00000270177 ENSG00000280104
GH05H133247 1.2 Ensembl ENCODE 9.7 +177.3 177326 5 ARNT GATA2 ZNF143 FOS ATF7 REST ZNF518A ZNF592 MEF2D SMARCA4 MIR1289-2 AFF4 ENSG00000250244 ENSG00000249478
GH05H133466 0.8 ENCODE 11.3 -39.9 -39939 2 ZSCAN5A HDGF ZNF473 SUZ12 ZNF493 ZSCAN4 ZNF266 KLF17 PLRG1 ZIC2 AFF4 ENSG00000202533 LOC105379175 CTB-3M24.3 ENSG00000271128 IL4 MIR1289-2 RAD50 ZCCHC10 ENSG00000280104
GH05H133941 0.9 ENCODE dbSUPER 9.8 -513.8 -513811 0 L3MBTL2 TAL1 NR4A1 DPF2 CDC5L RAD51 SMARCA4 NCOR1 MGA MIR1289-2 LOC105379182 WSPAR
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1289-2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1289-2 Gene

Chromosome:
5
Start:
133,427,596 bp from pter
End:
133,427,706 bp from pter
Size:
111 bases
Orientation:
Minus strand

Genomic View for MIR1289-2 Gene

Genes around MIR1289-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1289-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1289-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1289-2 Gene

ORGUL Member Location for MIR1289-2 Gene

ORGUL Member Location for MIR1289-2 gene

Proteins for MIR1289-2 Gene

Post-translational modifications for MIR1289-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1289-2 Gene

Domains & Families for MIR1289-2 Gene

Gene Families for MIR1289-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1289-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1289-2 Gene

Function for MIR1289-2 Gene

Phenotypes From GWAS Catalog for MIR1289-2 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR1289-2
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1289-2 Gene

Localization for MIR1289-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1289-2 Gene

Pathways & Interactions for MIR1289-2 Gene

SuperPathways for MIR1289-2 Gene

No Data Available

Interacting Proteins for MIR1289-2 Gene

Gene Ontology (GO) - Biological Process for MIR1289-2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1289-2 Gene

Drugs & Compounds for MIR1289-2 Gene

No Compound Related Data Available

Transcripts for MIR1289-2 Gene

mRNA/cDNA for MIR1289-2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR1289-2
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1289-2 Gene

No ASD Table

Relevant External Links for MIR1289-2 Gene

GeneLoc Exon Structure for
MIR1289-2
ECgene alternative splicing isoforms for
MIR1289-2

Expression for MIR1289-2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1289-2 Gene

genes like me logo Genes that share expression patterns with MIR1289-2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1289-2 Gene

Orthologs for MIR1289-2 Gene

Evolution for MIR1289-2 Gene

ENSEMBL:
Gene Tree for MIR1289-2 (if available)
TreeFam:
Gene Tree for MIR1289-2 (if available)

No data available for Orthologs for MIR1289-2 Gene

Paralogs for MIR1289-2 Gene

No data available for Paralogs for MIR1289-2 Gene

Variants for MIR1289-2 Gene

Sequence variations from dbSNP and Humsavar for MIR1289-2 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1001671885 -- 133,428,565(+) AACTG(A/G)CACCT intron-variant, upstream-variant-2KB
rs1001685564 -- 133,428,275(+) TCATA(C/T)GCATC intron-variant, upstream-variant-2KB
rs1002125560 -- 133,428,843(+) TGCAA(C/T)GCTTC intron-variant, upstream-variant-2KB
rs1003456331 -- 133,428,080(+) TGCTG(A/C)GTTGG intron-variant, upstream-variant-2KB
rs10060919 -- 133,428,025(+) AACTT(C/G)TGTGA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1289-2 Gene

Variant ID Type Subtype PubMed ID
nsv599716 CNV gain 21841781

Relevant External Links for MIR1289-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1289-2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1289-2 Gene

Disorders for MIR1289-2 Gene

Relevant External Links for MIR1289-2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1289-2

No disorders were found for MIR1289-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1289-2 Gene

Publications for MIR1289-2 Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR1289-2 Gene

Sources for MIR1289-2 Gene

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