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Aliases for MIR1289-2 Gene

Subcategory (RNA class) for MIR1289-2 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1289-2 Gene

  • MicroRNA 1289-2 2 3 5
  • Hsa-Mir-1289-2 3
  • MIRN1289-2 3

External Ids for MIR1289-2 Gene

Previous HGNC Symbols for MIR1289-2 Gene

  • MIRN1289-2

Previous GeneCards Identifiers for MIR1289-2 Gene

  • GC00U923069
  • GC05M132792
  • GC05M132763

Summaries for MIR1289-2 Gene

Entrez Gene Summary for MIR1289-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1289-2 Gene

MIR1289-2 (MicroRNA 1289-2) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1289-2 Gene

Genomics for MIR1289-2 Gene

Regulatory Elements for MIR1289-2 Gene

Enhancers for MIR1289-2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05F133456 1.4 Ensembl ENCODE 12 -29.4 -29413 2.2 MAX CEBPG RAD21 YY1 ZNF316 GATA3 CTBP1 GATA2 FOS ZNF652 MIR1289-2 ENSG00000270177 ENSG00000280104
GH05F133465 0.2 Ensembl 11.8 -38.4 -38395 1.0 ZFHX2 PKNOX1 PBX2 TRIM22 EGR2 MIR1289-2 ENSG00000280104 PIR50619
GH05F133459 0.4 Ensembl 11.6 -32.5 -32471 0.8 ZBTB10 CTCF ZNF654 REST ZNF2 RAD21 ZNF512 SMC3 NR2F6 ZBTB33 MIR1289-2 ENSG00000280104 PIR50619
GH05F133466 1.1 Ensembl ENCODE 11.2 -40.0 -39995 2.2 ZSCAN5A HDGF CTCF PKNOX1 ZNF493 ZNF266 KLF17 PLRG1 RAD21 ZIC2 CTB-3M24.3 ENSG00000271128 MIR1289-2 AFF4 RAD50 ZCCHC10 ENSG00000280104 PIR50619
GH05F133396 0.5 Ensembl ENCODE 10.8 +30.5 30531 2.1 SRF ZIC2 ATF2 RELA ZNF121 ELK1 EED MLLT1 KDM1A MIR1289-2 CTB-3M24.3 PIR54441
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR1289-2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1289-2 Gene

Chromosome:
5
Start:
133,427,596 bp from pter
End:
133,427,706 bp from pter
Size:
111 bases
Orientation:
Minus strand

Genomic View for MIR1289-2 Gene

Genes around MIR1289-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1289-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1289-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1289-2 Gene

ORGUL Member Location for MIR1289-2 Gene

ORGUL Member Location for MIR1289-2 gene

Proteins for MIR1289-2 Gene

Post-translational modifications for MIR1289-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1289-2 Gene

Domains & Families for MIR1289-2 Gene

Gene Families for MIR1289-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1289-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1289-2 Gene

Function for MIR1289-2 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1289-2 Gene

Localization for MIR1289-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1289-2 Gene

Pathways & Interactions for MIR1289-2 Gene

SuperPathways for MIR1289-2 Gene

No Data Available

Interacting Proteins for MIR1289-2 Gene

Gene Ontology (GO) - Biological Process for MIR1289-2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1289-2 Gene

Transcripts for MIR1289-2 Gene

mRNA/cDNA for MIR1289-2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1289-2 Gene

No ASD Table

Relevant External Links for MIR1289-2 Gene

GeneLoc Exon Structure for
MIR1289-2
ECgene alternative splicing isoforms for
MIR1289-2

Expression for MIR1289-2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1289-2 Gene

genes like me logo Genes that share expression patterns with MIR1289-2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR1289-2 Gene

Orthologs for MIR1289-2 Gene

Evolution for MIR1289-2 Gene

ENSEMBL:
Gene Tree for MIR1289-2 (if available)
TreeFam:
Gene Tree for MIR1289-2 (if available)

No data available for Orthologs for MIR1289-2 Gene

Paralogs for MIR1289-2 Gene

No data available for Paralogs for MIR1289-2 Gene

Variants for MIR1289-2 Gene

Sequence variations from dbSNP and Humsavar for MIR1289-2 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs10060919 -- 133,428,025(+) AACTT(C/G)TGTGA intron-variant, upstream-variant-2KB
rs112205652 -- 133,427,243(+) GCTCA(C/T)GTGCA intron-variant, downstream-variant-500B
rs112928293 -- 133,427,670(+) GAGGC(A/G/T)GGGTC intron-variant, nc-transcript-variant
rs113069169 -- 133,429,601(+) GGCCT(-/G)TCCTC intron-variant, upstream-variant-2KB
rs113327391 -- 133,427,223(+) TTCCC(C/T)AAGGA intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR1289-2 Gene

Variant ID Type Subtype PubMed ID
nsv599716 CNV gain 21841781

Relevant External Links for MIR1289-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1289-2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1289-2 Gene

Disorders for MIR1289-2 Gene

Relevant External Links for MIR1289-2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR1289-2

No disorders were found for MIR1289-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1289-2 Gene

Publications for MIR1289-2 Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR1289-2 Gene

Sources for MIR1289-2 Gene

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